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Latz, Eicke
One or more keywords matched the following items that are connected to
Latz, Eicke
Item Type
Name
Academic Article
Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent.
Academic Article
Comparative toll-like receptor 4-mediated innate host defense to Bordetella infection.
Academic Article
Cryptococcus neoformans glycoantigens are captured by multiple lectin receptors and presented by dendritic cells.
Academic Article
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.
Academic Article
The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation.
Academic Article
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Academic Article
TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA.
Academic Article
KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas.
Academic Article
Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers.
Academic Article
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Academic Article
Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2.
Academic Article
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Academic Article
LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
Academic Article
TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Academic Article
Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity.
Academic Article
Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition.
Academic Article
Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome.
Academic Article
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.
Academic Article
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Academic Article
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
Academic Article
The critical role of IL-1 receptor-associated kinase 4-mediated NF-?B activation in modified low-density lipoprotein-induced inflammatory gene expression and atherosclerosis.
Academic Article
Cutting edge: FAS (CD95) mediates noncanonical IL-1? and IL-18 maturation via caspase-8 in an RIP3-independent manner.
Academic Article
Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis.
Academic Article
Overexpression of membrane-bound fas ligand (CD95L) exacerbates autoimmune disease and renal pathology in pristane-induced lupus.
Concept
Mice, Inbred BALB C
Concept
Mice, Inbred C3H
Concept
Mice, Inbred C57BL
Concept
Mice, Inbred NOD
Concept
Mice, Inbred Strains
Academic Article
RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
Academic Article
High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.
Academic Article
Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
Academic Article
Inflammasome-dependent and -independent IL-18 production mediates immunity to the ISCOMATRIX adjuvant.
Academic Article
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Academic Article
Optimization of transcription factor binding map accuracy utilizing knockout-mouse models.
Academic Article
TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes.
Academic Article
Gadolinium-based compounds induce NLRP3-dependent IL-1? production and peritoneal inflammation.
Academic Article
CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis.
Academic Article
ATF3 Is a Key Regulator of Macrophage IFN Responses.
Academic Article
Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling.
Academic Article
Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition.
Academic Article
A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In?Vivo Infection.
Academic Article
TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus.
Academic Article
Ursodeoxycholic acid impairs atherogenesis and promotes plaque regression by cholesterol crystal dissolution in mice.
Academic Article
An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in?mice.
Academic Article
Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt-induced hypertension.
Academic Article
Soluble Uric Acid Activates the NLRP3 Inflammasome.
Academic Article
Human NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase.
Academic Article
Microglia-derived ASC specks cross-seed amyloid-? in Alzheimer's disease.
Academic Article
Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.
Academic Article
The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.
Academic Article
Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity.
Academic Article
Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension.
Academic Article
Charcot-Leyden Crystals Activate the NLRP3 Inflammasome and Cause IL-1? Inflammation in Human Macrophages.
Academic Article
Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model.
Academic Article
NLRP3 inflammasome-activating arginine-based liposomes promote antigen presentations in dendritic cells.
Academic Article
AIM2 inflammasome-derived IL-1? induces postoperative ileus in mice.
Academic Article
NLRP3 inflammasome activation drives tau pathology.
Academic Article
Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation.
Academic Article
Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase.
Academic Article
?-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia.
Academic Article
STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1? expression.
Academic Article
Bidirectional Role of NLRP3 During Acute and Chronic Cholestatic Liver Injury.
Academic Article
1-Deoxysphingolipids cause autophagosome and lysosome accumulation and trigger NLRP3 inflammasome activation.
Academic Article
Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury.
Academic Article
Macrophage inflammatory state in Type 1 diabetes: triggered by NLRP3/iNOS pathway and attenuated by docosahexaenoic acid.
Academic Article
Sensing soluble uric acid by Naip1-Nlrp3 platform.
Academic Article
Non-linear optical imaging of atherosclerotic plaques in the context of SIV and HIV infection prominently detects crystalline cholesterol esters.
Academic Article
Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages.
Academic Article
IL-18 (Interleukin-18) Produced by Renal Tubular Epithelial Cells Promotes Renal Inflammation and Injury During Deoxycorticosterone/Salt-Induced Hypertension in Mice.
Academic Article
Proteopathic tau primes and activates interleukin-1? via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway.
Academic Article
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.
Academic Article
BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity.
Academic Article
Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production.
Academic Article
NLRP6 Inflammasome Modulates Disease Progression in a Chronic-Plus-Binge Mouse Model of Alcoholic Liver Disease.
Academic Article
Tetracycline ameliorates silica-induced pulmonary inflammation and fibrosis via inhibition of caspase-1.
Academic Article
Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury.
Academic Article
PLK1 inhibition dampens NLRP3 inflammasome-elicited response in inflammatory disease models.
Academic Article
Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids.
Academic Article
Retention of ES cell-derived 129S genome drives NLRP1 hypersensitivity and transcriptional deregulation in Nlrp3tm1Flv mice.
Search Criteria
Mice Inbred A