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Latz, Eicke

One or more keywords matched the following items that are connected to Latz, Eicke

Item Type	Name
Academic Article	Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent.
Academic Article	Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
Academic Article	IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
Academic Article	Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.
Academic Article	Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.
Academic Article	The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
Academic Article	Comparative toll-like receptor 4-mediated innate host defense to Bordetella infection.
Academic Article	TLR9 and the recognition of self and non-self nucleic acids.
Academic Article	Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.
Academic Article	Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.
Academic Article	The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation.
Academic Article	TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA.
Academic Article	An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4.
Academic Article	Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts.
Academic Article	The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes.
Academic Article	Natural loss-of-function mutation of myeloid differentiation protein 88 disrupts its ability to form Myddosomes.
Academic Article	Optimal oligonucleotide sequences for TLR9 inhibitory activity in human cells: lack of correlation with TLR9 binding.
Academic Article	Innate immune receptors for nucleic acids.
Academic Article	Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers.
Academic Article	A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization.
Academic Article	Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2.
Academic Article	The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism.
Academic Article	Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling.
Academic Article	LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
Academic Article	Receptor "cross talk" in innate immunity.
Academic Article	Cell distributions and functions of Toll-like receptor 4 studied by fluorescent gene constructs.
Academic Article	TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Academic Article	Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity.
Academic Article	Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors.
Academic Article	Mechanisms of TLR9 activation.
Academic Article	Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.
Academic Article	Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity.
Academic Article	The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.
Academic Article	HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.
Academic Article	Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition.
Academic Article	Ligand-induced conformational changes allosterically activate Toll-like receptor 9.
Academic Article	Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.
Academic Article	Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi.
Academic Article	Toll-like receptor interactions imaged by FRET microscopy and GFP fragment reconstitution.
Academic Article	Alternating 2'-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist.
Academic Article	Differential cytokine production and bystander activation of autoreactive B cells in response to CpG-A and CpG-B oligonucleotides.
Academic Article	Rational design of immunostimulatory siRNAs.
Academic Article	Identification of a novel human MD-2 splice variant that negatively regulates Lipopolysaccharide-induced TLR4 signaling.
Academic Article	Up-regulation of TLR2 and TLR4 in dendritic cells in response to HIV type 1 and coinfection with opportunistic pathogens.
Academic Article	HIV type 1 infection up-regulates TLR2 and TLR4 expression and function in vivo and in vitro.
Academic Article	Direct measurement of the interaction force between immunostimulatory CpG-DNA and TLR9 fusion protein.
Academic Article	Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes.
Concept	Toll-Like Receptors
Concept	Toll-Like Receptor 4
Concept	Toll-Like Receptor 9
Concept	Toll-Like Receptor 3
Concept	Toll-Like Receptor 2
Concept	Toll-Like Receptor 7
Concept	Toll-Like Receptor 5
Concept	Toll-Like Receptor 1
Concept	Toll-Like Receptor 8
Academic Article	RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
Academic Article	High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.
Academic Article	Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo.
Academic Article	Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
Academic Article	The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4.
Academic Article	Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanisms.
Academic Article	Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8.
Academic Article	Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors.
Academic Article	Synergistic activation of Toll-like receptor 8 by two RNA degradation products.
Academic Article	TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes.
Academic Article	Nucleic acid-sensing TLRs and autoimmunity: novel insights from structural and cell biology.
Academic Article	Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use.
Academic Article	Toll-Like Receptor Interactions Measured by Microscopic and Flow Cytometric FRET.
Academic Article	TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus.
Academic Article	RAGE Enhances TLR Responses through Binding and Internalization of RNA.
Academic Article	TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects.
Academic Article	Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling.
Academic Article	The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.
Academic Article	CD82 controls CpG-dependent TLR9 signaling.
Academic Article	Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation.
Academic Article	Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase.
Academic Article	?-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia.
Academic Article	STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1? expression.
Academic Article	The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages.
Academic Article	Interaction of TLR4 and TLR8 in the Innate Immune Response against Mycobacterium Tuberculosis.
Academic Article	Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages.
Academic Article	Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct ?-Synuclein Assemblies.

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Toll Like Receptors