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Activation of the Drosophila MLK by ceramide reveals TNF-alpha and ceramide as agonists of mammalian MLK3.
De-regulation of JNK and JAK/STAT signaling in ESCRT-II mutant tissues cooperatively contributes to neoplastic tumorigenesis.
Drosophila mixed lineage kinase/slipper, a missing biochemical link in Drosophila JNK signaling.
Mitogen-Activated Protein Kinase Kinases
MAP Kinase Kinase Kinases
MAP Kinase Kinase 4
Genetic models of apoptosis-induced proliferation decipher activation of JNK and identify a requirement of EGFR signaling for tissue regenerative responses in Drosophila.
Killers creating new life: caspases drive apoptosis-induced proliferation in tissue repair and disease.
Tumor-promoting function of apoptotic caspases by an amplification loop involving ROS, macrophages and JNK in Drosophila.
Basement membrane damage by ROS- and JNK-mediated Mmp2 activation drives macrophage recruitment to overgrown tissue.
Mitogen Activated Protein Kinase Kinases