Item Type | Name |
Academic Article
|
Binding of the human immunodeficiency virus type 1 Gag polyprotein to cyclophilin A is mediated by the central region of capsid and requires Gag dimerization.
|
Academic Article
|
Cyclosporine A-resistant human immunodeficiency virus type 1 mutants demonstrate that Gag encodes the functional target of cyclophilin A.
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Academic Article
|
Assignment of cyclophilin A (PPIA) to human chromosome band 7p13by in situ hybridization.
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Academic Article
|
Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription.
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Academic Article
|
Cyclophilin A is required for the replication of group M human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus SIV(CPZ)GAB but not group O HIV-1 or other primate immunodeficiency viruses.
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Academic Article
|
Translation elongation factor 1-alpha interacts specifically with the human immunodeficiency virus type 1 Gag polyprotein.
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Academic Article
|
Basic residues in human immunodeficiency virus type 1 nucleocapsid promote virion assembly via interaction with RNA.
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Academic Article
|
Rescue of multiple viral functions by a second-site suppressor of a human immunodeficiency virus type 1 nucleocapsid mutation.
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Academic Article
|
Inhibition of HIV-1 replication by cyclosporine A or related compounds correlates with the ability to disrupt the Gag-cyclophilin A interaction.
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Academic Article
|
Human immunodeficiency virus type 1 virion density is not determined by nucleocapsid basic residues.
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Academic Article
|
Absconding with the chaperone: essential cyclophilin-Gag interaction in HIV-1 virions.
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Academic Article
|
Isolation, characterization and targeted disruption of mouse ppia: cyclophilin A is not essential for mammalian cell viability.
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Academic Article
|
The hydrophobic pocket of cyclophilin is the binding site for the human immunodeficiency virus type 1 Gag polyprotein.
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Academic Article
|
Context-dependent phenotype of a human immunodeficiency virus type 1 nucleocapsid mutation.
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Academic Article
|
Specific incorporation of heat shock protein 70 family members into primate lentiviral virions.
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Academic Article
|
Cyclophilin A peptidyl-prolyl isomerase activity promotes ZPR1 nuclear export.
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Academic Article
|
As(2)O(3) enhances retroviral reverse transcription and counteracts Ref1 antiviral activity.
|
Academic Article
|
Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors.
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Academic Article
|
Production of ribosome components in effector CD4+ T cells is accelerated by TCR stimulation and coordinated by ERK-MAPK.
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Academic Article
|
AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis.
|
Academic Article
|
HIV-1 Vpr induces defects in mitosis, cytokinesis, nuclear structure, and centrosomes.
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Academic Article
|
Blockade of late stages of autoimmune diabetes by inhibition of the receptor for advanced glycation end products.
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Academic Article
|
Lv1 inhibition of human immunodeficiency virus type 1 is counteracted by factors that stimulate synthesis or nuclear translocation of viral cDNA.
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Academic Article
|
Target cell cyclophilin A modulates human immunodeficiency virus type 1 infectivity.
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Academic Article
|
Human immunodeficiency virus type 1 Gag polyprotein multimerization requires the nucleocapsid domain and RNA and is promoted by the capsid-dimer interface and the basic region of matrix protein.
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Academic Article
|
Disruption of human TRIM5alpha antiviral activity by nonhuman primate orthologues.
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Academic Article
|
TRIM5alpha selectively binds a restriction-sensitive retroviral capsid.
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Academic Article
|
TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs.
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Academic Article
|
Binding of human immunodeficiency virus type 1 (HIV-1) RNA to recombinant HIV-1 gag polyprotein.
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Academic Article
|
G2 cell cycle arrest and cyclophilin A in lentiviral gene transfer.
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Academic Article
|
Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cells.
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Academic Article
|
Vif counteracts a cyclophilin A-imposed inhibition of simian immunodeficiency viruses in human cells.
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Academic Article
|
Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia.
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Academic Article
|
HIV-1 infection: going nuclear with TNPO3/Transportin-SR2 and integrase.
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Academic Article
|
Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cells.
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Academic Article
|
An invariant surface patch on the TRIM5alpha PRYSPRY domain is required for retroviral restriction but dispensable for capsid binding.
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Academic Article
|
The double-stranded RNA binding domain of the vaccinia virus E3L protein inhibits both RNA- and DNA-induced activation of interferon beta.
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Academic Article
|
Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components.
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Academic Article
|
Human cellular restriction factors that target HIV-1 replication.
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Academic Article
|
Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1.
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Academic Article
|
HIV-1 and Ebola virus: the getaway driver nabbed.
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Academic Article
|
Cyclosporine blocks incorporation of HIV-1 envelope glycoprotein into virions.
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Academic Article
|
p62/sequestosome-1 associates with and sustains the expression of retroviral restriction factor TRIM5alpha.
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Academic Article
|
Cyclosporine A-sensitive, cyclophilin B-dependent endoplasmic reticulum-associated degradation.
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Academic Article
|
Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection.
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Academic Article
|
Deciphering the code for retroviral integration target site selection.
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Academic Article
|
TRIM22 inhibits HIV-1 transcription independently of its E3 ubiquitin ligase activity, Tat, and NF-kappaB-responsive long terminal repeat elements.
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Academic Article
|
TRIM5 is an innate immune sensor for the retrovirus capsid lattice.
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Academic Article
|
TRIM5a associates with proteasomal subunits in cells while in complex with HIV-1 virions.
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Academic Article
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Inhibition of HIV-1 infection by TNPO3 depletion is determined by capsid and detectable after viral cDNA enters the nucleus.
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Academic Article
|
Envelope-dependent, cyclophilin-independent effects of glycosaminoglycans on human immunodeficiency virus type 1 attachment and infection.
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Academic Article
|
TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity.
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Academic Article
|
The carboxyl-terminus of human immunodeficiency virus type 2 circulating recombinant form 01_AB capsid protein affects sensitivity to human TRIM5a.
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Academic Article
|
More than one way to TRIM a capsid.
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Academic Article
|
TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm.
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Academic Article
|
Cyclophilin A interacts with HIV-1 Vpr and is required for its functional expression.
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Academic Article
|
The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest.
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Academic Article
|
Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1.
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Academic Article
|
Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk.
|
Academic Article
|
Selection for loss of Ref1 activity in human cells releases human immunodeficiency virus type 1 from cyclophilin A dependence during infection.
|
Academic Article
|
Covalent modification of human immunodeficiency virus type 1 p6 by SUMO-1.
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Academic Article
|
ATPgammaS disrupts human immunodeficiency virus type 1 virion core integrity.
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Academic Article
|
Cyclophilin A-deficient mice are resistant to immunosuppression by cyclosporine.
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Academic Article
|
Cyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cells.
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Academic Article
|
Arsenic counteracts human immunodeficiency virus type 1 restriction by various TRIM5 orthologues in a cell type-dependent manner.
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Academic Article
|
Cyclophilin A and TRIM5alpha independently regulate human immunodeficiency virus type 1 infectivity in human cells.
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Academic Article
|
Cyclophilin, TRIM5, and innate immunity to HIV-1.
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Academic Article
|
Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infection.
|
Academic Article
|
The retroviral restriction factor TRIM5alpha.
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Academic Article
|
The role of lysine 186 in HIV-1 integrase multimerization.
|
Academic Article
|
A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal.
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Academic Article
|
Lentiviral vector gene transfer is limited by the proteasome at postentry steps in various types of stem cells.
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Academic Article
|
Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics.
|
Academic Article
|
HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation.
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Academic Article
|
Cyclophilin B interacts with sodium-potassium ATPase and is required for pump activity in proximal tubule cells of the kidney.
|
Academic Article
|
Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon.
|
Academic Article
|
Nef decreases HIV-1 sensitivity to neutralizing antibodies that target the membrane-proximal external region of TMgp41.
|
Academic Article
|
TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling.
|
Academic Article
|
TRIM5 and the Regulation of HIV-1 Infectivity.
|
Academic Article
|
Innate immune sensing of HIV-1 by dendritic cells.
|
Academic Article
|
HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency.
|
Academic Article
|
Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay.
|
Academic Article
|
Cyclophilin binding to the human immunodeficiency virus type 1 Gag polyprotein is mimicked by an anti-cyclosporine antibody.
|
Academic Article
|
Cyclophilin and gag in HIV-1 replication and pathogenesis.
|
Academic Article
|
Specific incorporation of cyclophilin A into HIV-1 virions.
|
Academic Article
|
Specific binding of human immunodeficiency virus type 1 gag polyprotein and nucleocapsid protein to viral RNAs detected by RNA mobility shift assays.
|
Academic Article
|
Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B.
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Concept
|
Cytokines
|
Concept
|
T-Lymphocytes, Cytotoxic
|
Concept
|
Disease Models, Animal
|
Concept
|
SOXB1 Transcription Factors
|
Concept
|
Drug Resistance, Viral
|
Concept
|
Temperature
|
Concept
|
beta Karyopherins
|
Concept
|
Genes, env
|
Concept
|
Subcellular Fractions
|
Concept
|
Interferon-beta
|
Concept
|
Hypoxia-Ischemia, Brain
|
Concept
|
NF-kappa B
|
Concept
|
Heat-Shock Proteins
|
Concept
|
Endogenous Retroviruses
|
Concept
|
Software
|
Concept
|
Neuregulins
|
Concept
|
Mitochondria
|
Concept
|
Flow Cytometry
|
Concept
|
CD4 Antigens
|
Concept
|
Introns
|
Concept
|
HeLa Cells
|
Concept
|
Diphtheria-Tetanus-Pertussis Vaccine
|
Concept
|
Exodeoxyribonucleases
|
Concept
|
Hepacivirus
|
Concept
|
Cell Nucleus
|
Concept
|
Cell Division
|
Concept
|
Amino Acid Isomerases
|
Concept
|
Antigens, Differentiation
|
Concept
|
Gene Expression
|
Concept
|
COS Cells
|
Concept
|
Macrophage Activation
|
Concept
|
Peptide Elongation Factor 1
|
Concept
|
DNA Helicases
|
Concept
|
Cats
|
Concept
|
Forkhead Transcription Factors
|
Concept
|
RNA Interference
|
Concept
|
Retinoblastoma Protein
|
Concept
|
DNA, Complementary
|
Concept
|
Fluorescent Antibody Technique
|
Concept
|
Interleukin-15
|
Concept
|
CD8-Positive T-Lymphocytes
|
Concept
|
Disulfides
|
Concept
|
Antigen-Antibody Complex
|
Concept
|
RNA, Catalytic
|
Concept
|
Carbamates
|
Concept
|
Chromosomes
|
Concept
|
Genes, gag
|
Concept
|
HSP70 Heat-Shock Proteins
|
Concept
|
Electrophoresis, Gel, Two-Dimensional
|
Concept
|
Sodium-Potassium-Exchanging ATPase
|
Concept
|
Endonucleases
|
Concept
|
GTP-Binding Proteins
|
Concept
|
Genomics
|
Concept
|
Antibodies, Neutralizing
|
Concept
|
Cricetinae
|
Concept
|
Polyribosomes
|
Concept
|
Cyclins
|
Concept
|
Chromosome Banding
|
Concept
|
Lysosomes
|
Concept
|
Retroelements
|
Concept
|
Interferons
|
Concept
|
Endoplasmic Reticulum
|
Concept
|
Jurkat Cells
|
Concept
|
Chi-Square Distribution
|
Concept
|
Genes, nef
|
Concept
|
Tropism
|
Concept
|
Carrier Proteins
|
Concept
|
Dendritic Cells
|
Concept
|
Genes
|
Concept
|
DNA-(Apurinic or Apyrimidinic Site) Lyase
|
Concept
|
Centrosome
|
Concept
|
Reverse Transcription
|
Concept
|
Africa, Western
|
Concept
|
Adenosine Triphosphate
|
Concept
|
Protein Biosynthesis
|
Concept
|
Amino Acid Sequence
|
Concept
|
Molecular Dynamics Simulation
|
Concept
|
Algorithms
|
Concept
|
Two-Hybrid System Techniques
|
Concept
|
CDC2 Protein Kinase
|
Concept
|
Cohort Studies
|
Concept
|
Seasons
|
Concept
|
Nuclear Envelope
|
Concept
|
BCG Vaccine
|
Concept
|
Boston
|
Concept
|
Antineoplastic Agents
|
Concept
|
Calcium
|
Concept
|
Cytidine Deaminase
|
Concept
|
Mycophenolic Acid
|
Concept
|
Antibodies, Viral
|
Concept
|
CHO Cells
|
Concept
|
Blotting, Western
|
Concept
|
Cancer Vaccines
|
Concept
|
Cyclosporins
|
Concept
|
Papillomavirus Vaccines
|
Concept
|
Enhancer Elements, Genetic
|
Concept
|
Genetic Predisposition to Disease
|
Concept
|
Protein Interaction Domains and Motifs
|
Concept
|
T-Lymphocyte Subsets
|
Concept
|
Tumor Cells, Cultured
|
Concept
|
Mitosis
|
Concept
|
Typhoid Fever
|
Concept
|
Chromatin
|
Concept
|
Monomeric GTP-Binding Proteins
|
Concept
|
Chromosomes, Human, Pair 7
|
Concept
|
Salmonella typhi
|
Concept
|
Culture Media, Serum-Free
|
Concept
|
Cell Line, Transformed
|
Concept
|
DNA Primers
|
Concept
|
Cysteine
|
Concept
|
Pseudogenes
|
Concept
|
Umbilical Veins
|
Concept
|
Nuclear Pore
|
Concept
|
Histocytochemistry
|
Concept
|
Aminocoumarins
|
Concept
|
Respiratory Syncytial Virus Vaccines
|
Concept
|
Transcription, Genetic
|
Concept
|
HIV Envelope Protein gp120
|
Concept
|
Dimerization
|
Concept
|
Repressor Proteins
|
Concept
|
HIV Protease
|
Concept
|
Octamer Transcription Factor-3
|
Concept
|
Exons
|
Concept
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rab GTP-Binding Proteins
|
Concept
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Plasma Cells
|
Concept
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Muromonab-CD3
|
Concept
|
Centrifugation, Isopycnic
|
Concept
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Cell Polarity
|
Concept
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Cheirogaleidae
|
Concept
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Computational Biology
|
Concept
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Cells, Cultured
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Concept
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Colitis, Ulcerative
|
Concept
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T Cell Transcription Factor 1
|
Concept
|
Cell Separation
|
Concept
|
T-Lymphocytes
|
Concept
|
Hemorrhagic Fever, Ebola
|
Concept
|
Calcineurin
|
Concept
|
Herpesvirus 4, Human
|
Concept
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Cytoplasm
|
Concept
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Capsid
|
Concept
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Lymphocyte Culture Test, Mixed
|
Concept
|
Antigens, CD
|
Concept
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Monocytes
|
Concept
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Viral Load
|
Concept
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Interleukin-2
|
Concept
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Glutathione Transferase
|
Concept
|
Cell Proliferation
|
Concept
|
Homeodomain Proteins
|
Concept
|
CpG Islands
|
Concept
|
Subtilisins
|
Concept
|
Escherichia coli
|
Concept
|
Ribonuclease, Pancreatic
|
Concept
|
Potassium Chloride
|
Concept
|
Adaptor Proteins, Signal Transducing
|
Concept
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Flavivirus Infections
|
Concept
|
DEAD-box RNA Helicases
|
Concept
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Lymphocytes
|
Concept
|
Zinc Fingers
|
Concept
|
Vero Cells
|
Concept
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Genes, Reporter
|
Concept
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Vaccinia virus
|
Concept
|
Nucleocapsid
|
Concept
|
Transcription Factor AP-1
|
Concept
|
Neutralization Tests
|
Concept
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Antibodies, Monoclonal
|
Concept
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Cell Membrane
|
Concept
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Crystallography, X-Ray
|
Concept
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Liver Transplantation
|
Concept
|
Cluster Analysis
|
Concept
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Virology
|
Concept
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Detergents
|
Concept
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Green Fluorescent Proteins
|
Concept
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Lymphocyte Activation
|
Concept
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Cyclosporine
|
Concept
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Convalescence
|
Concept
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Endosomes
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Concept
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Capsid Proteins
|
Concept
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Carcinoma
|
Concept
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Ribonucleases
|
Concept
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Influenza Vaccines
|
Concept
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Leukocytes, Mononuclear
|
Concept
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Colorado
|
Concept
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Interferon-alpha
|
Concept
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K562 Cells
|
Concept
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Mass Screening
|
Concept
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DNA Probes
|
Concept
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Quantitative Trait Loci
|
Concept
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Genes, Essential
|
Concept
|
Carbon-Oxygen Lyases
|
Concept
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Japan
|
Concept
|
Fluorescence Resonance Energy Transfer
|
Concept
|
Trichloroacetic Acid
|
Concept
|
CD4-Positive T-Lymphocytes
|
Concept
|
Radioimmunoprecipitation Assay
|
Concept
|
Vaccinia
|
Concept
|
Flavivirus
|
Concept
|
3' Untranslated Regions
|
Concept
|
Sequence Homology, Amino Acid
|
Concept
|
Diabetes Mellitus, Type 1
|
Concept
|
Thermogenesis
|
Concept
|
Contact Tracing
|
Concept
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Staining and Labeling
|
Concept
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Genistein
|
Concept
|
Genome-Wide Association Study
|
Concept
|
Ions
|
Concept
|
Proteomics
|
Concept
|
HIV Antibodies
|
Concept
|
Th2 Cells
|
Concept
|
Embryonic Stem Cells
|
Concept
|
Callithrix
|
Concept
|
AIDS Vaccines
|
Concept
|
Chaperonins
|
Concept
|
Peptide Hydrolases
|
Concept
|
Cell Line
|
Concept
|
Adenosine Triphosphatases
|
Concept
|
STAT1 Transcription Factor
|
Concept
|
B-Lymphocytes
|
Concept
|
Coronavirus Infections
|
Concept
|
Buffers
|
Concept
|
beta-Galactosidase
|
Concept
|
DNA-Directed RNA Polymerases
|
Concept
|
Peptidyl-Dipeptidase A
|
Concept
|
Proteasome Endopeptidase Complex
|
Concept
|
Spindle Apparatus
|
Concept
|
Bayes Theorem
|
Concept
|
Virion
|
Concept
|
Long Interspersed Nucleotide Elements
|
Concept
|
Colon
|
Concept
|
In Situ Hybridization, Fluorescence
|
Concept
|
Trypsin
|
Concept
|
Octoxynol
|
Concept
|
Epstein-Barr Virus Infections
|
Concept
|
Ebolavirus
|
Concept
|
Promoter Regions, Genetic
|
Concept
|
HIV Envelope Protein gp41
|
Concept
|
Gene Silencing
|
Concept
|
Vimentin
|
Concept
|
Cyclic AMP
|
Concept
|
Base Sequence
|
Concept
|
Alleles
|
Concept
|
RNA Probes
|
Concept
|
Zebrafish
|
Concept
|
Oxides
|
Concept
|
Killer Cells, Natural
|
Concept
|
Interferon Type I
|
Concept
|
Cyclophilins
|
Concept
|
Cold Temperature
|
Concept
|
Measles-Mumps-Rubella Vaccine
|
Concept
|
Cell Line, Tumor
|
Concept
|
Molecular Sequence Data
|
Concept
|
Carbazoles
|
Concept
|
DNA Transposable Elements
|
Concept
|
SAIDS Vaccines
|
Concept
|
Genes, vpr
|
Concept
|
SUMO-1 Protein
|
Academic Article
|
Overcoming current limitations in humanized mouse research.
|
Academic Article
|
The fate of HIV-1 capsid: a biochemical assay for HIV-1 uncoating.
|
Academic Article
|
TRIM5a and TRIM22 are differentially regulated according to HIV-1 infection phase and compartment.
|
Academic Article
|
Cyclophilin A promotes HIV-1 reverse transcription but its effect on transduction correlates best with its effect on nuclear entry of viral cDNA.
|
Academic Article
|
Vpx rescue of HIV-1 from the antiviral state in mature dendritic cells is independent of the intracellular deoxynucleotide concentration.
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Academic Article
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Gammaretroviral pol sequences act in cis to direct polysome loading and NXF1/NXT-dependent protein production by gag-encoded RNA.
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Academic Article
|
Processing strategies and software solutions for data-independent acquisition in mass spectrometry.
|
Academic Article
|
Optimization of human dendritic cell sample preparation for mass spectrometry-based proteomic studies.
|
Academic Article
|
Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration.
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Academic Article
|
The Use of Variable Q1 Isolation Windows Improves Selectivity in LC-SWATH-MS Acquisition.
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Academic Article
|
HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation.
|
Academic Article
|
Ranking Fragment Ions Based on Outlier Detection for Improved Label-Free Quantification in Data-Independent Acquisition LC-MS/MS.
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Academic Article
|
TRIM5 Retroviral Restriction Activity Correlates with the Ability To Induce Innate Immune Signaling.
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Academic Article
|
HIV-1 capsid is involved in post-nuclear entry steps.
|
Academic Article
|
Closing the net on retroviruses.
|
Academic Article
|
End Sequence Analysis Toolkit (ESAT) expands the extractable information from single-cell RNA-seq data.
|
Academic Article
|
Ebola Virus Glycoprotein with Increased Infectivity Dominated the 2013-2016 Epidemic.
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Academic Article
|
Optimization by infusion of multiple reaction monitoring transitions for sensitive quantification of peptides by liquid chromatography/mass spectrometry.
|
Academic Article
|
HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded.
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Academic Article
|
Comparative Analysis of Immune Cells Reveals a Conserved Regulatory Lexicon.
|
Academic Article
|
The Three-Fold Axis of the HIV-1 Capsid Lattice Is the Species-Specific Binding Interface for TRIM5a.
|
Academic Article
|
Primate immunodeficiency virus proteins Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex.
|
Academic Article
|
Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines.
|
Academic Article
|
Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1.
|
Academic Article
|
Constrained Mutational Sampling of Amino Acids in HIV-1 Protease Evolution.
|
Academic Article
|
Enhanced Cas12a editing in mammalian cells and zebrafish.
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Academic Article
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The hidden cost of genetic resistance to HIV-1.
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Academic Article
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TRIM5a Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation.
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Academic Article
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Retraction Note: The hidden cost of genetic resistance to HIV-1.
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Academic Article
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The piRNA Response to Retroviral Invasion of the Koala Genome.
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Academic Article
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Cyclophilin A protects HIV-1 from restriction by human TRIM5a.
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Academic Article
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Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111.
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Academic Article
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Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics.
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Academic Article
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Conformational changes in the Ebola virus membrane fusion machine induced by pH, Ca2+, and receptor binding.
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Academic Article
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HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells.
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Academic Article
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TRIM34 restricts HIV-1 and SIV capsids in a TRIM5a-dependent manner.
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Academic Article
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Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.
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Academic Article
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Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis.
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Academic Article
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The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines.
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Academic Article
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Phylogenetic analysis of SARS-CoV-2 in the Boston area highlights the role of recurrent importation and superspreading events.
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Academic Article
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Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.
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Academic Article
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The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines.
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Academic Article
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Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events.
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Academic Article
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Innate lymphoid cells and disease tolerance in SARS-CoV-2 infection.
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Academic Article
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SARS-CoV-2 Reinfection in a Liver Transplant Recipient.
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Academic Article
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Lessons from a local effort to screen for SARS-CoV-2.
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Academic Article
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Targeting of the Tec Kinase ITK Drives Resolution of T Cell-Mediated Colitis and Emerges as Potential Therapeutic Option in Ulcerative Colitis.
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Academic Article
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Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity.
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Academic Article
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AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma.
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Academic Article
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Genome-wide functional screen of 3'UTR variants uncovers causal variants for human disease and evolution.
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Academic Article
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Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike.
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Academic Article
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Consulting the Oracle of SARS-CoV-2 Infection.
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Concept
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Nanog Homeobox Protein
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Concept
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Sequestosome-1 Protein
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Concept
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DEAD Box Protein 58
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Concept
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APOBEC-3G Deaminase
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Concept
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Regulatory Factor X Transcription Factors
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Concept
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X-Box Binding Protein 1
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Concept
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Protein Domains
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Concept
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Interferon-Induced Helicase, IFIH1
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Concept
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Gene Editing
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Concept
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Protein Conformation, alpha-Helical
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Concept
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Intraepithelial Lymphocytes
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Concept
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SAM Domain and HD Domain-Containing Protein 1
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Concept
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ATPases Associated with Diverse Cellular Activities
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Concept
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Valosin Containing Protein
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Concept
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HEK293 Cells
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Concept
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Single-Cell Analysis
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Concept
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Transcriptome
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Concept
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Asymptomatic Infections
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Concept
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Pandemics
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Concept
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Argonaute Proteins
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Concept
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CTLA-4 Antigen
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Concept
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Antibodies, Monoclonal, Humanized
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Concept
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Primary Cell Culture
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Concept
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Sf9 Cells
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Concept
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Calcineurin Inhibitors
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Concept
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Clustered Regularly Interspaced Short Palindromic Repeats
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Concept
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CRISPR-Cas Systems
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Concept
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Fatty Acid Synthases
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Concept
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Myxovirus Resistance Proteins
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Concept
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Amphiregulin
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Academic Article
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Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness.
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Academic Article
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Vaccine Breakthrough Infection with the SARS-CoV-2 Delta or Omicron (BA.1) Variant Leads to Distinct Profiles of Neutralizing Antibody Responses.
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Academic Article
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Innate lymphoid cells and COVID-19 severity in SARS-CoV-2 infection.
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Academic Article
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Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike.
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Academic Article
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Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness.
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Academic Article
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Vaccine breakthrough infection leads to distinct profiles of neutralizing antibody responses by SARS-CoV-2 variant.
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Academic Article
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The 2022 RSV surge was driven by multiple viral lineages.
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Academic Article
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Multimodal surveillance of SARS-CoV-2 at a university enables development of a robust outbreak response framework.
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Academic Article
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Regulation of Ebola GP conformation and membrane binding by the chemical environment of the late endosome.
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Academic Article
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Purification and structure of luminal domain C of human Niemann-Pick C1 protein.
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Academic Article
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Viral Lineages in the 2022 RSV Surge in the United States.
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Academic Article
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S:D614G and S:H655Y are gateway mutations that act epistatically to promote SARS-CoV-2 variant fitness.
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Academic Article
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Detergent modulates the conformational equilibrium of SARS-CoV-2 Spike during cryo-EM structural determination.
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Academic Article
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Transcriptional and chromatin profiling of human blood innate lymphoid cell subsets sheds light on HIV-1 pathogenesis.
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Academic Article
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Reducing the inherent auto-inhibitory interaction within the pegRNA enhances prime editing efficiency.
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Academic Article
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The HIV-1 capsid core is an opportunistic nuclear import receptor.
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Academic Article
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Cytotoxic CD4 development requires CD4 effectors to concurrently recognize local antigen and encounter type I IFN-induced IL-15.
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Academic Article
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Emerging role of cyclophilin A in HIV-1 infection: from producer cell to the target cell nucleus.
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Academic Article
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Addressing the dNTP bottleneck restricting prime editing activity.
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Academic Article
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Cytotoxic CD4 development requires CD4 effectors to concurrently recognize local antigen and encounter type I IFN-induced IL-15.
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Academic Article
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Regulation of Ebola GP conformation and membrane binding by the chemical environment of the late endosome.
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Academic Article
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IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus.
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Academic Article
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Natural history of Ebola virus disease in rhesus monkeys shows viral variant emergence dynamics and tissue-specific host responses.
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Academic Article
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Optimization of Nuclear Localization Signal Composition Improves CRISPR-Cas12a Editing Rates in Human Primary Cells.
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Academic Article
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Cyclophilin A Facilitates HIV-1 DNA Integration.
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Academic Article
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IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus.
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Academic Article
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PRC1.6 localizes on chromatin with the human silencing hub (HUSH) complex for promoter-specific silencing.
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Academic Article
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Increasing intracellular dNTP levels improves prime editing efficiency.
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Academic Article
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Cyclophilin A facilitates HIV-1 integration.
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Academic Article
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piRNA Defense Against Endogenous Retroviruses.
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Academic Article
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The Trajectory of KoRV-A Evolution Indicates Initial Integration into the Koala Germline Genome Near Coffs Harbour.
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Academic Article
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Correction for Kajaste-Rudnitski et al., "TRIM22 Inhibits HIV-1 Transcription Independently of Its E3 Ubiquitin Ligase Activity, Tat, and NF-?B-Responsive Long Terminal Repeat Elements".
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Academic Article
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Molecular basis for the increased fusion activity of the Ebola virus glycoprotein epidemic variant A82V: Insights from simulations and experiments.
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Academic Article
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Evolution of KoRV-A transcriptional silencing in wild koalas.
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Academic Article
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Computationally designed proteins mimic antibody immune evasion in viral evolution.
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