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Academic Article
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Binding of the human immunodeficiency virus type 1 Gag polyprotein to cyclophilin A is mediated by the central region of capsid and requires Gag dimerization.
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Academic Article
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Cyclosporine A-resistant human immunodeficiency virus type 1 mutants demonstrate that Gag encodes the functional target of cyclophilin A.
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Academic Article
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Assignment of cyclophilin A (PPIA) to human chromosome band 7p13by in situ hybridization.
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Academic Article
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Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription.
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Academic Article
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Cyclophilin A is required for the replication of group M human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus SIV(CPZ)GAB but not group O HIV-1 or other primate immunodeficiency viruses.
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Academic Article
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Basic residues in human immunodeficiency virus type 1 nucleocapsid promote virion assembly via interaction with RNA.
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Academic Article
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Inhibition of HIV-1 replication by cyclosporine A or related compounds correlates with the ability to disrupt the Gag-cyclophilin A interaction.
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Academic Article
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Absconding with the chaperone: essential cyclophilin-Gag interaction in HIV-1 virions.
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Academic Article
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The hydrophobic pocket of cyclophilin is the binding site for the human immunodeficiency virus type 1 Gag polyprotein.
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Academic Article
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Genetic assay for multimerization of retroviral gag polyproteins.
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Academic Article
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Cyclophilin A peptidyl-prolyl isomerase activity promotes ZPR1 nuclear export.
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Academic Article
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Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors.
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Academic Article
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Human immunodeficiency virus type 1 Gag polyprotein multimerization requires the nucleocapsid domain and RNA and is promoted by the capsid-dimer interface and the basic region of matrix protein.
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Academic Article
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Disruption of human TRIM5alpha antiviral activity by nonhuman primate orthologues.
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Academic Article
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Vif counteracts a cyclophilin A-imposed inhibition of simian immunodeficiency viruses in human cells.
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Academic Article
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Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia.
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Academic Article
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An invariant surface patch on the TRIM5alpha PRYSPRY domain is required for retroviral restriction but dispensable for capsid binding.
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Academic Article
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The double-stranded RNA binding domain of the vaccinia virus E3L protein inhibits both RNA- and DNA-induced activation of interferon beta.
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Academic Article
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Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components.
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Academic Article
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Human cellular restriction factors that target HIV-1 replication.
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Academic Article
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HIV-1 and Ebola virus: the getaway driver nabbed.
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Academic Article
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p62/sequestosome-1 associates with and sustains the expression of retroviral restriction factor TRIM5alpha.
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Academic Article
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Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection.
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Academic Article
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TRIM5 is an innate immune sensor for the retrovirus capsid lattice.
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Academic Article
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TRIM5a associates with proteasomal subunits in cells while in complex with HIV-1 virions.
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Academic Article
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The carboxyl-terminus of human immunodeficiency virus type 2 circulating recombinant form 01_AB capsid protein affects sensitivity to human TRIM5a.
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Academic Article
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Cyclophilin A interacts with HIV-1 Vpr and is required for its functional expression.
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Academic Article
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The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest.
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Academic Article
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Mapping of functionally important residues of a cysteine-histidine box in the human immunodeficiency virus type 1 nucleocapsid protein.
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Academic Article
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Selection for loss of Ref1 activity in human cells releases human immunodeficiency virus type 1 from cyclophilin A dependence during infection.
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Academic Article
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Covalent modification of human immunodeficiency virus type 1 p6 by SUMO-1.
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Academic Article
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Arsenic counteracts human immunodeficiency virus type 1 restriction by various TRIM5 orthologues in a cell type-dependent manner.
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Academic Article
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Cyclophilin A and TRIM5alpha independently regulate human immunodeficiency virus type 1 infectivity in human cells.
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Academic Article
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Cyclophilin, TRIM5, and innate immunity to HIV-1.
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Academic Article
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Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infection.
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Academic Article
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A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal.
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Academic Article
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Cyclophilin B interacts with sodium-potassium ATPase and is required for pump activity in proximal tubule cells of the kidney.
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Academic Article
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TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling.
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Academic Article
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Innate immune sensing of HIV-1 by dendritic cells.
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Academic Article
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HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency.
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Academic Article
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Cyclophilin binding to the human immunodeficiency virus type 1 Gag polyprotein is mimicked by an anti-cyclosporine antibody.
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Academic Article
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Cyclophilin and gag in HIV-1 replication and pathogenesis.
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Academic Article
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Specific incorporation of cyclophilin A into HIV-1 virions.
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Academic Article
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Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B.
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Concept
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Protein Binding
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Concept
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DNA-Binding Proteins
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Concept
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Nucleocytoplasmic Transport Proteins
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Concept
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GTP-Binding Proteins
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Concept
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Carrier Proteins
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Concept
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Monomeric GTP-Binding Proteins
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Concept
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rab GTP-Binding Proteins
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Concept
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RNA-Binding Proteins
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Academic Article
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TRIM5a and TRIM22 are differentially regulated according to HIV-1 infection phase and compartment.
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Academic Article
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Cyclophilin A promotes HIV-1 reverse transcription but its effect on transduction correlates best with its effect on nuclear entry of viral cDNA.
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Academic Article
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Vpx rescue of HIV-1 from the antiviral state in mature dendritic cells is independent of the intracellular deoxynucleotide concentration.
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Academic Article
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Gammaretroviral pol sequences act in cis to direct polysome loading and NXF1/NXT-dependent protein production by gag-encoded RNA.
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Academic Article
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HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation.
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Academic Article
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TRIM5 Retroviral Restriction Activity Correlates with the Ability To Induce Innate Immune Signaling.
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Academic Article
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Closing the net on retroviruses.
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Academic Article
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Ebola Virus Glycoprotein with Increased Infectivity Dominated the 2013-2016 Epidemic.
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Academic Article
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HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded.
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Academic Article
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The Three-Fold Axis of the HIV-1 Capsid Lattice Is the Species-Specific Binding Interface for TRIM5a.
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Academic Article
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Primate immunodeficiency virus proteins Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex.
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Academic Article
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TRIM5a Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation.
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Academic Article
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Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics.
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Academic Article
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Conformational changes in the Ebola virus membrane fusion machine induced by pH, Ca2+, and receptor binding.
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Academic Article
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TRIM34 restricts HIV-1 and SIV capsids in a TRIM5a-dependent manner.
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Academic Article
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AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma.
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Concept
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X-Box Binding Protein 1
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