Item Type | Name |
Academic Article
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Binding of the human immunodeficiency virus type 1 Gag polyprotein to cyclophilin A is mediated by the central region of capsid and requires Gag dimerization.
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Academic Article
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Cyclosporine A-resistant human immunodeficiency virus type 1 mutants demonstrate that Gag encodes the functional target of cyclophilin A.
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Academic Article
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Assignment of cyclophilin A (PPIA) to human chromosome band 7p13by in situ hybridization.
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Academic Article
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Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription.
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Academic Article
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The HIV type 1 replication block in nonhuman primates is not explained by differences in cyclophilin A primary structure.
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Academic Article
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Cyclophilin A is required for the replication of group M human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus SIV(CPZ)GAB but not group O HIV-1 or other primate immunodeficiency viruses.
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Academic Article
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Translation elongation factor 1-alpha interacts specifically with the human immunodeficiency virus type 1 Gag polyprotein.
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Academic Article
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Basic residues in human immunodeficiency virus type 1 nucleocapsid promote virion assembly via interaction with RNA.
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Academic Article
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Rescue of multiple viral functions by a second-site suppressor of a human immunodeficiency virus type 1 nucleocapsid mutation.
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Academic Article
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Inhibition of HIV-1 replication by cyclosporine A or related compounds correlates with the ability to disrupt the Gag-cyclophilin A interaction.
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Academic Article
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Human immunodeficiency virus type 1 virion density is not determined by nucleocapsid basic residues.
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Academic Article
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Absconding with the chaperone: essential cyclophilin-Gag interaction in HIV-1 virions.
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Academic Article
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Isolation, characterization and targeted disruption of mouse ppia: cyclophilin A is not essential for mammalian cell viability.
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Academic Article
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The hydrophobic pocket of cyclophilin is the binding site for the human immunodeficiency virus type 1 Gag polyprotein.
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Academic Article
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Genetic assay for multimerization of retroviral gag polyproteins.
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Academic Article
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Specific incorporation of heat shock protein 70 family members into primate lentiviral virions.
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Academic Article
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Cyclophilin A peptidyl-prolyl isomerase activity promotes ZPR1 nuclear export.
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Academic Article
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As(2)O(3) enhances retroviral reverse transcription and counteracts Ref1 antiviral activity.
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Academic Article
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Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors.
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Academic Article
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Production of ribosome components in effector CD4+ T cells is accelerated by TCR stimulation and coordinated by ERK-MAPK.
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Academic Article
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AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis.
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Academic Article
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HIV-1 Vpr induces defects in mitosis, cytokinesis, nuclear structure, and centrosomes.
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Academic Article
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Target cell cyclophilin A modulates human immunodeficiency virus type 1 infectivity.
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Academic Article
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Human immunodeficiency virus type 1 Gag polyprotein multimerization requires the nucleocapsid domain and RNA and is promoted by the capsid-dimer interface and the basic region of matrix protein.
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Academic Article
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Disruption of human TRIM5alpha antiviral activity by nonhuman primate orthologues.
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Academic Article
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Binding of human immunodeficiency virus type 1 (HIV-1) RNA to recombinant HIV-1 gag polyprotein.
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Academic Article
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Vif counteracts a cyclophilin A-imposed inhibition of simian immunodeficiency viruses in human cells.
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Academic Article
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Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia.
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Academic Article
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Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cells.
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Academic Article
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An invariant surface patch on the TRIM5alpha PRYSPRY domain is required for retroviral restriction but dispensable for capsid binding.
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Academic Article
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The double-stranded RNA binding domain of the vaccinia virus E3L protein inhibits both RNA- and DNA-induced activation of interferon beta.
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Academic Article
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Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components.
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Academic Article
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Human cellular restriction factors that target HIV-1 replication.
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Academic Article
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Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1.
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Academic Article
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HIV-1 and Ebola virus: the getaway driver nabbed.
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Academic Article
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p62/sequestosome-1 associates with and sustains the expression of retroviral restriction factor TRIM5alpha.
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Academic Article
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Cyclosporine A-sensitive, cyclophilin B-dependent endoplasmic reticulum-associated degradation.
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Academic Article
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Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection.
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Academic Article
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TRIM22 inhibits HIV-1 transcription independently of its E3 ubiquitin ligase activity, Tat, and NF-kappaB-responsive long terminal repeat elements.
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Academic Article
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TRIM5 is an innate immune sensor for the retrovirus capsid lattice.
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Academic Article
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TRIM5a associates with proteasomal subunits in cells while in complex with HIV-1 virions.
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Academic Article
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Inhibition of HIV-1 infection by TNPO3 depletion is determined by capsid and detectable after viral cDNA enters the nucleus.
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Academic Article
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Envelope-dependent, cyclophilin-independent effects of glycosaminoglycans on human immunodeficiency virus type 1 attachment and infection.
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Academic Article
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TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity.
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Academic Article
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The carboxyl-terminus of human immunodeficiency virus type 2 circulating recombinant form 01_AB capsid protein affects sensitivity to human TRIM5a.
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Academic Article
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More than one way to TRIM a capsid.
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Academic Article
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TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm.
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Academic Article
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Cyclophilin A interacts with HIV-1 Vpr and is required for its functional expression.
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Academic Article
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The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest.
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Academic Article
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Mapping of functionally important residues of a cysteine-histidine box in the human immunodeficiency virus type 1 nucleocapsid protein.
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Academic Article
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Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1.
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Academic Article
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Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk.
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Academic Article
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Selection for loss of Ref1 activity in human cells releases human immunodeficiency virus type 1 from cyclophilin A dependence during infection.
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Academic Article
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Covalent modification of human immunodeficiency virus type 1 p6 by SUMO-1.
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Academic Article
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ATPgammaS disrupts human immunodeficiency virus type 1 virion core integrity.
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Academic Article
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Cyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cells.
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Academic Article
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Arsenic counteracts human immunodeficiency virus type 1 restriction by various TRIM5 orthologues in a cell type-dependent manner.
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Academic Article
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Cyclophilin A and TRIM5alpha independently regulate human immunodeficiency virus type 1 infectivity in human cells.
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Academic Article
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Cyclophilin, TRIM5, and innate immunity to HIV-1.
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Academic Article
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Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infection.
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Academic Article
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The role of lysine 186 in HIV-1 integrase multimerization.
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Academic Article
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A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal.
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Academic Article
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Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics.
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Academic Article
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HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation.
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Academic Article
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Cyclophilin B interacts with sodium-potassium ATPase and is required for pump activity in proximal tubule cells of the kidney.
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Academic Article
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Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon.
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Academic Article
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Nef decreases HIV-1 sensitivity to neutralizing antibodies that target the membrane-proximal external region of TMgp41.
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Academic Article
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TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling.
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Academic Article
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Innate immune sensing of HIV-1 by dendritic cells.
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Academic Article
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HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency.
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Academic Article
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Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay.
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Academic Article
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Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B.
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Academic Article
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Cyclophilin binding to the human immunodeficiency virus type 1 Gag polyprotein is mimicked by an anti-cyclosporine antibody.
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Academic Article
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Cyclophilin and gag in HIV-1 replication and pathogenesis.
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Academic Article
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Linker insertion mutations in the human immunodeficiency virus type 1 gag gene: effects on virion particle assembly, release, and infectivity.
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Academic Article
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The yeast two-hybrid system for studying protein-protein interactions.
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Academic Article
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Specific incorporation of cyclophilin A into HIV-1 virions.
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Academic Article
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Specificity and sequence requirements for interactions between various retroviral Gag proteins.
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Academic Article
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Mutational analysis of cis-acting packaging signals in human immunodeficiency virus type 1 RNA.
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Academic Article
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Specific binding of human immunodeficiency virus type 1 gag polyprotein and nucleocapsid protein to viral RNAs detected by RNA mobility shift assays.
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Academic Article
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Effect of linker insertion mutations in the human immunodeficiency virus type 1 gag gene on activation of viral protease expressed in bacteria.
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Academic Article
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Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B.
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Concept
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Protein-Tyrosine Kinases
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Concept
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Membrane Proteins
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Concept
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Viral Regulatory and Accessory Proteins
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Concept
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Protein Binding
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Concept
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Protein Subunits
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Concept
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Protein Transport
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Concept
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DNA-Binding Proteins
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Concept
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Nucleocytoplasmic Transport Proteins
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Concept
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Protein Folding
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Concept
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Protein Processing, Post-Translational
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Concept
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Heat-Shock Proteins
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Concept
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Ubiquitin-Protein Ligases
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Concept
|
Mutant Chimeric Proteins
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Concept
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Mitogen-Activated Protein Kinases
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Concept
|
Nuclear Pore Complex Proteins
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Concept
|
Retinoblastoma Protein
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Concept
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HSP70 Heat-Shock Proteins
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Concept
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GTP-Binding Proteins
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Concept
|
Human Immunodeficiency Virus Proteins
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Concept
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Protein Kinase Inhibitors
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Concept
|
Carrier Proteins
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Concept
|
Cell Cycle Proteins
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Concept
|
Luminescent Proteins
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Concept
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Protein Biosynthesis
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Concept
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Protein Interaction Mapping
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Concept
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CDC2 Protein Kinase
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Concept
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Nuclear Proteins
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Concept
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Recombinant Proteins
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Concept
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Protein Precursors
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Concept
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Protein Interaction Domains and Motifs
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Concept
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Intracellular Signaling Peptides and Proteins
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Concept
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Protein Denaturation
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Concept
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Monomeric GTP-Binding Proteins
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Concept
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HIV Envelope Protein gp120
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Concept
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Viral Proteins
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Concept
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Repressor Proteins
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Concept
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rab GTP-Binding Proteins
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Concept
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Retroviridae Proteins
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Concept
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Proteins
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Concept
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Zebrafish Proteins
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Concept
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Homeodomain Proteins
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Concept
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Oncogene Proteins, Viral
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Concept
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Viral Core Proteins
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Concept
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Protein Structure, Tertiary
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Concept
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Adaptor Proteins, Signal Transducing
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Concept
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Viral Structural Proteins
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Concept
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Protein Multimerization
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Concept
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Co-Repressor Proteins
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Concept
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Green Fluorescent Proteins
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Concept
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Recombinant Fusion Proteins
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Concept
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Capsid Proteins
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Concept
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Viral Nonstructural Proteins
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Concept
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Protein Structure, Quaternary
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Concept
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Fungal Proteins
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Concept
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Saccharomyces cerevisiae Proteins
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Concept
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Neoplasm Proteins
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Concept
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Drosophila Proteins
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Concept
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Protein Sorting Signals
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Concept
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Viral Matrix Proteins
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Concept
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Viral Fusion Proteins
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Concept
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beta-Transducin Repeat-Containing Proteins
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Concept
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Protein Conformation
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Concept
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Nucleocapsid Proteins
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Concept
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HIV Envelope Protein gp41
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Concept
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Viral Envelope Proteins
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Concept
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Cullin Proteins
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Concept
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Protein Engineering
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Concept
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HIV Core Protein p24
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Concept
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RNA-Binding Proteins
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Concept
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SUMO-1 Protein
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Academic Article
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The fate of HIV-1 capsid: a biochemical assay for HIV-1 uncoating.
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Academic Article
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TRIM5a and TRIM22 are differentially regulated according to HIV-1 infection phase and compartment.
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Academic Article
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Cyclophilin A promotes HIV-1 reverse transcription but its effect on transduction correlates best with its effect on nuclear entry of viral cDNA.
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Academic Article
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Vpx rescue of HIV-1 from the antiviral state in mature dendritic cells is independent of the intracellular deoxynucleotide concentration.
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Academic Article
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Gammaretroviral pol sequences act in cis to direct polysome loading and NXF1/NXT-dependent protein production by gag-encoded RNA.
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Academic Article
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Optimization of human dendritic cell sample preparation for mass spectrometry-based proteomic studies.
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Academic Article
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HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation.
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Academic Article
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TRIM5 Retroviral Restriction Activity Correlates with the Ability To Induce Innate Immune Signaling.
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Academic Article
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HIV-1 capsid is involved in post-nuclear entry steps.
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Academic Article
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Closing the net on retroviruses.
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Academic Article
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Ebola Virus Glycoprotein with Increased Infectivity Dominated the 2013-2016 Epidemic.
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Academic Article
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HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded.
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Academic Article
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The Three-Fold Axis of the HIV-1 Capsid Lattice Is the Species-Specific Binding Interface for TRIM5a.
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Academic Article
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Primate immunodeficiency virus proteins Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex.
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Academic Article
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Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1.
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Academic Article
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Enhanced Cas12a editing in mammalian cells and zebrafish.
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Academic Article
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TRIM5a Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation.
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Academic Article
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Cyclophilin A protects HIV-1 from restriction by human TRIM5a.
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Academic Article
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Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111.
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Academic Article
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Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics.
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Academic Article
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Conformational changes in the Ebola virus membrane fusion machine induced by pH, Ca2+, and receptor binding.
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Academic Article
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TRIM34 restricts HIV-1 and SIV capsids in a TRIM5a-dependent manner.
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Academic Article
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Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.
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Academic Article
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Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis.
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Academic Article
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Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.
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Academic Article
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Targeting of the Tec Kinase ITK Drives Resolution of T Cell-Mediated Colitis and Emerges as Potential Therapeutic Option in Ulcerative Colitis.
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Academic Article
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Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity.
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Academic Article
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AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma.
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Concept
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Tripartite Motif Proteins
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Concept
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Uncoupling Protein 1
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Concept
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Nanog Homeobox Protein
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Concept
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Sequestosome-1 Protein
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Concept
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DEAD Box Protein 58
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Concept
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X-Box Binding Protein 1
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Concept
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Protein Domains
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Concept
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Protein Conformation, alpha-Helical
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Concept
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SAM Domain and HD Domain-Containing Protein 1
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Concept
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Valosin Containing Protein
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Concept
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GPI-Linked Proteins
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Concept
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Argonaute Proteins
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Concept
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Myxovirus Resistance Proteins
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Academic Article
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Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike.
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Academic Article
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Purification and structure of luminal domain C of human Niemann-Pick C1 protein.
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Academic Article
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Detergent modulates the conformational equilibrium of SARS-CoV-2 Spike during cryo-EM structural determination.
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Academic Article
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The HIV-1 capsid core is an opportunistic nuclear import receptor.
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Academic Article
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Emerging role of cyclophilin A in HIV-1 infection: from producer cell to the target cell nucleus.
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Academic Article
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Regulation of Ebola GP conformation and membrane binding by the chemical environment of the late endosome.
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Academic Article
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IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus.
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Academic Article
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Cyclophilin A facilitates HIV-1 integration.
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Academic Article
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piRNA Defense Against Endogenous Retroviruses.
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