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Kurt Yilmaz, Nese

One or more keywords matched the following items that are connected to Kurt Yilmaz, Nese

Item Type	Name
Academic Article	Extreme entropy-enthalpy compensation in a drug-resistant variant of HIV-1 protease.
Academic Article	Cooperative effects of drug-resistance mutations in the flap region of HIV-1 protease.
Academic Article	Structural and thermodynamic basis of amprenavir/darunavir and atazanavir resistance in HIV-1 protease with mutations at residue 50.
Concept	Drug Resistance, Viral
Academic Article	Substrate envelope-designed potent HIV-1 protease inhibitors to avoid drug resistance.
Academic Article	HIV-1 protease-substrate coevolution in nelfinavir resistance.
Academic Article	Drug resistance conferred by mutations outside the active site through alterations in the dynamic and structural ensemble of HIV-1 protease.
Academic Article	Structural basis and distal effects of Gag substrate coevolution in drug resistance to HIV-1 protease.
Academic Article	Improving Viral Protease Inhibitors to Counter Drug Resistance.
Academic Article	Molecular and Dynamic Mechanism Underlying Drug Resistance in Genotype 3 Hepatitis C NS3/4A Protease.
Academic Article	Molecular Basis for Differential Patterns of Drug Resistance in Influenza N1 and N2 Neuraminidase.
Academic Article	Hepatitis C Virus NS3/4A Protease Inhibitors Incorporating Flexible P2 Quinoxalines Target Drug Resistant Viral Variants.
Academic Article	Hydration Structure and Dynamics of Inhibitor-Bound HIV-1 Protease.
Academic Article	Probing Structural Changes among Analogous Inhibitor-Bound Forms of HIV-1 Protease and a Drug-Resistant Mutant in Solution by Nuclear Magnetic Resonance.
Academic Article	NMR and MD studies combined to elucidate inhibitor and water interactions of HIV-1 protease and their modulations with resistance mutations.
Academic Article	Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
Academic Article	Molecular Determinants of Epistasis in HIV-1 Protease: Elucidating the Interdependence of L89V and L90M Mutations in Resistance.
Academic Article	Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors.
Academic Article	Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond.
Academic Article	Deciphering Complex Mechanisms of Resistance and Loss of Potency through Coupled Molecular Dynamics and Machine Learning.
Academic Article	Discovery of Quinoxaline-Based P1-P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants.
Academic Article	Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance.

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Drug Resistance Viral