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One or more keywords matched the following items that are connected to Fitzgerald, Katherine
Item TypeName
Academic Article Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.
Academic Article Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction.
Academic Article IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
Academic Article The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
Academic Article The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.
Academic Article Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.
Academic Article Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.
Academic Article Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance.
Academic Article The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Academic Article Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Academic Article Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens.
Academic Article Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.
Academic Article An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans.
Academic Article A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.
Academic Article IKKalpha negatively regulates IRF-5 function in a MyD88-TRAF6 pathway.
Academic Article Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome.
Academic Article Catenin' on to nucleic acid sensing.
Academic Article Inflammasomes and anti-viral immunity.
Academic Article Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation.
Academic Article A novel role for the NLRC4 inflammasome in mucosal defenses against the fungal pathogen Candida albicans.
Academic Article Activation of autophagy by inflammatory signals limits IL-1? production by targeting ubiquitinated inflammasomes for destruction.
Academic Article Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Academic Article Immunology. Select inflammasome assembly.
Academic Article TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria.
Academic Article Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1?.
Academic Article The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.
Academic Article Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function.
Academic Article CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Academic Article LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
Academic Article IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts.
Academic Article TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Academic Article Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors.
Academic Article The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades.
Academic Article Endotoxin recognition and signal transduction by the TLR4/MD2-complex.
Academic Article Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence.
Academic Article Dengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion.
Academic Article AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.
Academic Article Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Academic Article Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.
Academic Article Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome.
Academic Article The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.
Academic Article NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Academic Article Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
Academic Article Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling.
Academic Article Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus.
Academic Article Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.
Academic Article Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.
Academic Article Aim2 deficiency in mice suppresses the expression of the inhibitory Fcgamma receptor (FcgammaRIIB) through the induction of the IFN-inducible p202, a lupus susceptibility protein.
Academic Article Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice.
Academic Article Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor.
Academic Article NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1? and neuronal toxicity.
Concept Protein Binding
Concept DNA-Binding Proteins
Concept Phosphate-Binding Proteins
Concept Periplasmic Binding Proteins
Concept ral GTP-Binding Proteins
Concept GTP-Binding Proteins
Concept Carrier Proteins
Concept rab GTP-Binding Proteins
Concept CCAAT-Enhancer-Binding Protein-beta
Concept Membrane Transport Proteins
Concept Calcium-Binding Proteins
Concept CCAAT-Enhancer-Binding Proteins
Concept RNA-Binding Proteins
Academic Article Synthetic oligodeoxynucleotides containing suppressive TTAGGG motifs inhibit AIM2 inflammasome activation.
Academic Article Cutting edge: Mycobacterium tuberculosis but not nonvirulent mycobacteria inhibits IFN-? and AIM2 inflammasome-dependent IL-1? production via its ESX-1 secretion system.
Academic Article Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome.
Academic Article Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome.
Academic Article Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1? production.
Academic Article Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.
Academic Article Recognition of cytosolic DNA by cGAS and other STING-dependent sensors.
Academic Article Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
Academic Article Rift Valley fever virus infection induces activation of the NLRP3 inflammasome.
Academic Article Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
Academic Article NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING.
Academic Article Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.
Academic Article Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome.
Academic Article TRIM13 is a negative regulator of MDA5-mediated type I interferon production.
Academic Article RNA and ?-hemolysin of group B Streptococcus induce interleukin-1? (IL-1?) by activating NLRP3 inflammasomes in mouse macrophages.
Academic Article TRIL is involved in cytokine production in the brain following Escherichia coli infection.
Academic Article Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1? production in response to ?-glucans and the fungal pathogen, Candida albicans.
Academic Article IKK? negatively regulates ASC-dependent inflammasome activation.
Academic Article Identification of Aim2 as a sensor for DNA vaccines.
Academic Article Cutting edge: AIM2 and endosomal TLRs differentially regulate arthritis and autoantibody production in DNase II-deficient mice.
Academic Article GBPs take AIM at Francisella.
Academic Article Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3.
Academic Article Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease.
Academic Article Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage.
Academic Article An unexpected role for RNA-sensing toll-like receptors in a murine model of DNA accrual.
Academic Article Gadolinium-based compounds induce NLRP3-dependent IL-1? production and peritoneal inflammation.
Academic Article Cutting Edge: DNA in the Lung Microenvironment during Influenza Virus Infection Tempers Inflammation by Engaging the DNA Sensor AIM2.
Academic Article Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II-/-IFNaR-/- Mice.
Academic Article The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury.
Academic Article Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis.
Academic Article Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
Academic Article CNBP controls IL-12 gene transcription and Th1 immunity.
Academic Article Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM.
Academic Article Gasdermins and their role in immunity and inflammation.
Academic Article Long non-coding RNAs in antiviral immunity.
Academic Article Succination inactivates gasdermin D and blocks pyroptosis.
Academic Article HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation.
Academic Article Cellular nucleic acid-binding protein is essential for type I interferon-mediated immunity to RNA virus infection.
Academic Article AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma.
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  • Carrier Proteins