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One or more keywords matched the following items that are connected to Fitzgerald, Katherine
Item TypeName
Academic Article Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.
Academic Article Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction.
Academic Article IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
Academic Article DUBbing down innate immunity.
Academic Article The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
Academic Article The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.
Academic Article The role of the interleukin-1/Toll-like receptor superfamily in inflammation and host defence.
Academic Article Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.
Academic Article Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance.
Academic Article Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination.
Academic Article Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5.
Academic Article Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens.
Academic Article A novel IFN regulatory factor 3-dependent pathway activated by trypanosomes triggers IFN-beta in macrophages and fibroblasts.
Academic Article TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA.
Academic Article Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.
Academic Article Role of p38 and early growth response factor 1 in the macrophage response to group B streptococcus.
Academic Article A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.
Academic Article NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis.
Academic Article Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling.
Academic Article IKKalpha negatively regulates IRF-5 function in a MyD88-TRAF6 pathway.
Academic Article Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling.
Academic Article Differential gene expression downstream of Toll-like receptors (TLRs): role of c-Src and activating transcription factor 3 (ATF3).
Academic Article Catenin' on to nucleic acid sensing.
Academic Article Induction and inhibition of type I interferon responses by distinct components of lymphocytic choriomeningitis virus.
Academic Article DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation.
Academic Article Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING.
Academic Article Role of interferon regulatory factor 7 in T cell responses during acute lymphocytic choriomeningitis virus infection.
Academic Article LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
Academic Article IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts.
Academic Article TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Academic Article TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression.
Academic Article Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors.
Academic Article The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades.
Academic Article Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence.
Academic Article Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation.
Academic Article Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex.
Academic Article Sorting out Toll signals.
Academic Article Toll-like receptor-dependent and -independent viperin gene expression and counter-regulation by PRDI-binding factor-1/BLIMP1.
Academic Article NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.
Academic Article Role of MyD88 in route-dependent susceptibility to vesicular stomatitis virus infection.
Academic Article The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis.
Academic Article Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.
Academic Article Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling.
Academic Article Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus.
Academic Article Absence of MyD88 results in enhanced TLR3-dependent phosphorylation of IRF3 and increased IFN-? and RANTES production.
Academic Article Regulation of lipopolysaccharide-induced translation of tumor necrosis factor-alpha by the toll-like receptor 4 adaptor protein TRAM.
Academic Article Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome.
Academic Article Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway.
Academic Article Resistance to HSV-1 infection in the epithelium resides with the novel innate sensor, IFI-16.
Academic Article 5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential.
Academic Article Interferon-? and granulocyte/monocyte colony-stimulating factor production by natural killer cells involves different signaling pathways and the adaptor stimulator of interferon genes (STING).
Academic Article Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid.
Concept Hepatocyte Nuclear Factor 4
Concept TNF Receptor-Associated Factor 6
Concept Transcription Factor CHOP
Concept Transcription Factor RelB
Concept TNF Receptor-Associated Factor 2
Concept Receptor Activator of Nuclear Factor-kappa B
Concept Myeloid Differentiation Factor 88
Concept Interferon-Stimulated Gene Factor 3
Concept Interferon Regulatory Factor-7
Concept Microphthalmia-Associated Transcription Factor
Concept STAT3 Transcription Factor
Concept Activating Transcription Factor 3
Concept Receptors, Tumor Necrosis Factor, Type II
Concept Tumor Necrosis Factor-alpha
Concept Granulocyte-Macrophage Colony-Stimulating Factor
Concept Interferon Regulatory Factor-3
Concept Interferon Regulatory Factor-1
Concept Transcription Factor AP-1
Concept Receptors, Tumor Necrosis Factor, Type I
Concept STAT6 Transcription Factor
Concept STAT1 Transcription Factor
Concept Activating Transcription Factor 4
Concept Receptors, Tumor Necrosis Factor
Concept Transcription Factor RelA
Academic Article The transcriptional repressor BLIMP1 curbs host defenses by suppressing expression of the chemokine CCL8.
Academic Article Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome.
Academic Article STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease.
Academic Article Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection.
Academic Article Antiviral autophagy restrictsRift Valley fever virus infection and is conserved from flies to mammals.
Academic Article TRIF signaling is essential for TLR4-driven IgE class switching.
Academic Article TRIM13 is a negative regulator of MDA5-mediated type I interferon production.
Academic Article TRIL is involved in cytokine production in the brain following Escherichia coli infection.
Academic Article STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.
Academic Article A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling.
Academic Article Suppression of systemic autoimmunity by the innate immune adaptor STING.
Academic Article GBPs take AIM at Francisella.
Academic Article Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3.
Academic Article Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease.
Academic Article Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage.
Academic Article A cGAS-Independent STING/IRF7 Pathway Mediates the Immunogenicity of DNA Vaccines.
Academic Article Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes.
Academic Article Cyclic GMP-AMP Synthase Is the Cytosolic Sensor of Plasmodium falciparum Genomic DNA and Activates Type I IFN in Malaria.
Academic Article IRF3 and type I interferons fuel a fatal response to myocardial infarction.
Academic Article Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.
Academic Article Immature lung TNFR2- conventional DC 2 subpopulation activates moDCs to promote cyclic di-GMP mucosal adjuvant responses in vivo.
Academic Article STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1? expression.
Academic Article The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans.
Academic Article Cellular nucleic acid-binding protein is essential for type I interferon-mediated immunity to RNA virus infection.
Concept Regulatory Factor X Transcription Factors
Concept Tumor Necrosis Factor alpha-Induced Protein 3
Concept Positive Regulatory Domain I-Binding Factor 1
Academic Article Lymphocyte crosstalk is required for monocyte-intrinsic trained immunity to Plasmodium falciparum.
Academic Article Epithelial HNF4A shapes the intraepithelial lymphocyte compartment via direct regulation of immune signaling molecules.
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