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Fitzgerald, Katherine

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Item Type	Name
Academic Article	Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.
Academic Article	Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction.
Academic Article	IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
Academic Article	Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response.
Academic Article	DUBbing down innate immunity.
Academic Article	The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
Academic Article	The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.
Academic Article	TOLLing away in Brazil.
Academic Article	The role of the interleukin-1/Toll-like receptor superfamily in inflammation and host defence.
Academic Article	Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.
Academic Article	Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.
Academic Article	Immunology. The shape of things to come.
Academic Article	Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance.
Academic Article	The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Academic Article	Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Academic Article	Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5.
Academic Article	Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens.
Academic Article	A novel IFN regulatory factor 3-dependent pathway activated by trypanosomes triggers IFN-beta in macrophages and fibroblasts.
Academic Article	TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA.
Academic Article	Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.
Academic Article	Role of p38 and early growth response factor 1 in the macrophage response to group B streptococcus.
Academic Article	An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans.
Academic Article	A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.
Academic Article	NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis.
Academic Article	Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling.
Academic Article	IKKalpha negatively regulates IRF-5 function in a MyD88-TRAF6 pathway.
Academic Article	Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling.
Academic Article	Differential gene expression downstream of Toll-like receptors (TLRs): role of c-Src and activating transcription factor 3 (ATF3).
Academic Article	TLR4 is a negative regulator in noninfectious lung inflammation.
Academic Article	Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome.
Academic Article	Catenin' on to nucleic acid sensing.
Academic Article	Induction and inhibition of type I interferon responses by distinct components of lymphocytic choriomeningitis virus.
Academic Article	Inflammasomes and anti-viral immunity.
Academic Article	The interferon inducible gene: Viperin.
Academic Article	Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation.
Academic Article	A novel role for the NLRC4 inflammasome in mucosal defenses against the fungal pathogen Candida albicans.
Academic Article	Activation of autophagy by inflammatory signals limits IL-1? production by targeting ubiquitinated inflammasomes for destruction.
Academic Article	Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Academic Article	Immunology. Select inflammasome assembly.
Academic Article	Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING.
Academic Article	Serine/threonine acetylation of TGF?-activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling.
Academic Article	TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria.
Academic Article	Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1?.
Academic Article	SnapShot: inflammasomes.
Academic Article	The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.
Academic Article	Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function.
Academic Article	CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Academic Article	The Toll-IL-1 receptor adaptor family grows to five members.
Academic Article	LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
Academic Article	IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts.
Academic Article	TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Academic Article	Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1.
Academic Article	TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression.
Academic Article	Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors.
Academic Article	The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades.
Academic Article	Endotoxin recognition and signal transduction by the TLR4/MD2-complex.
Academic Article	Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence.
Academic Article	Dengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion.
Academic Article	Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation.
Academic Article	Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex.
Academic Article	The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.
Academic Article	Sorting out Toll signals.
Academic Article	Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling.
Academic Article	Toll-like receptor-dependent and -independent viperin gene expression and counter-regulation by PRDI-binding factor-1/BLIMP1.
Academic Article	RIG-I: tri-ing to discriminate between self and non-self RNA.
Academic Article	NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.
Academic Article	Salmonella-induced SipB-independent cell death requires Toll-like receptor-4 signalling via the adapter proteins Tram and Trif.
Academic Article	The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis.
Academic Article	AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.
Academic Article	Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Academic Article	Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.
Academic Article	Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.
Academic Article	Cell type-specific recognition of human metapneumoviruses (HMPVs) by retinoic acid-inducible gene I (RIG-I) and TLR7 and viral interference of RIG-I ligand recognition by HMPV-B1 phosphoprotein.
Academic Article	NLR-containing inflammasomes: central mediators of host defense and inflammation.
Academic Article	Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome.
Academic Article	The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.
Academic Article	NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Academic Article	Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
Academic Article	Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling.
Academic Article	Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus.
Academic Article	Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.
Academic Article	Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.
Academic Article	Regulation of lipopolysaccharide-induced translation of tumor necrosis factor-alpha by the toll-like receptor 4 adaptor protein TRAM.
Academic Article	Aim2 deficiency in mice suppresses the expression of the inhibitory Fcgamma receptor (FcgammaRIIB) through the induction of the IFN-inducible p202, a lupus susceptibility protein.
Academic Article	Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice.
Academic Article	Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome.
Academic Article	Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway.
Academic Article	The PYHIN protein family as mediators of host defenses.
Academic Article	Resistance to HSV-1 infection in the epithelium resides with the novel innate sensor, IFI-16.
Academic Article	Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor.
Academic Article	The NLRP12 inflammasome recognizes Yersinia pestis.
Academic Article	NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1? and neuronal toxicity.
Academic Article	5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential.
Academic Article	Cutting edge: FAS (CD95) mediates noncanonical IL-1? and IL-18 maturation via caspase-8 in an RIP3-independent manner.
Academic Article	Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins.
Academic Article	RNA helicase signaling is critical for type i interferon production and protection against Rift Valley fever virus during mucosal challenge.
Academic Article	Interferon-? and granulocyte/monocyte colony-stimulating factor production by natural killer cells involves different signaling pathways and the adaptor stimulator of interferon genes (STING).
Academic Article	Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid.
Academic Article	Overexpression of membrane-bound fas ligand (CD95L) exacerbates autoimmune disease and renal pathology in pristane-induced lupus.
Academic Article	An alternative pathway of T-cell activation: a functional role for the 50 kd T11 sheep erythrocyte receptor protein.
Concept	Nod Signaling Adaptor Proteins
Concept	Protein-Tyrosine Kinases
Concept	Membrane Proteins
Concept	Protein Binding
Concept	Protein Transport
Concept	Hemolysin Proteins
Concept	DNA-Binding Proteins
Concept	Serum Amyloid A Protein
Concept	Protein Folding
Concept	Protein Processing, Post-Translational
Concept	Ubiquitin-Protein Ligases
Concept	Proto-Oncogene Proteins c-rel
Concept	Phosphate-Binding Proteins
Concept	Unfolded Protein Response
Concept	Mitogen-Activated Protein Kinases
Concept	p38 Mitogen-Activated Protein Kinases
Concept	Periplasmic Binding Proteins
Concept	Mitogen-Activated Protein Kinase Kinases
Concept	ral GTP-Binding Proteins
Concept	GTP-Binding Proteins
Concept	Mitogen-Activated Protein Kinase 1
Concept	Carrier Proteins
Concept	Proto-Oncogene Proteins c-bcl-2
Concept	Luminescent Proteins
Concept	Protein Biosynthesis
Concept	Receptors, G-Protein-Coupled
Concept	Nuclear Proteins
Concept	Recombinant Proteins
Concept	Protein Kinases
Concept	Protein Interaction Domains and Motifs
Concept	S100 Proteins
Concept	Intracellular Signaling Peptides and Proteins
Concept	BH3 Interacting Domain Death Agonist Protein
Concept	Mitogen-Activated Protein Kinase 3
Concept	ets-Domain Protein Elk-1
Concept	Viral Proteins
Concept	Intercellular Signaling Peptides and Proteins
Concept	Repressor Proteins
Concept	Xenopus Proteins
Concept	rab GTP-Binding Proteins
Concept	Protein Kinase C
Concept	Immediate-Early Proteins
Concept	CCAAT-Enhancer-Binding Protein-beta
Concept	Nod2 Signaling Adaptor Protein
Concept	Myelin Proteins
Concept	Proto-Oncogene Proteins c-akt
Concept	Proteins
Concept	Early Growth Response Protein 1
Concept	Fas-Associated Death Domain Protein
Concept	Protein Kinase C-epsilon
Concept	Receptor-Interacting Protein Serine-Threonine Kinases
Concept	Homeodomain Proteins
Concept	Suppressor of Cytokine Signaling Proteins
Concept	Ribosomal Proteins
Concept	Membrane Transport Proteins
Concept	Cytoskeletal Proteins
Concept	Protein Structure, Tertiary
Concept	Adaptor Proteins, Signal Transducing
Concept	Protein Modification, Translational
Concept	Interleukin 1 Receptor Antagonist Protein
Concept	Protein Multimerization
Concept	Escherichia coli Proteins
Concept	Green Fluorescent Proteins
Concept	Bacterial Proteins
Concept	Recombinant Fusion Proteins
Concept	Calcium-Binding Proteins
Concept	Viral Nonstructural Proteins
Concept	Plant Proteins
Concept	Protein Structure, Quaternary
Concept	Proto-Oncogene Proteins c-jun
Concept	Drosophila Proteins
Concept	CCAAT-Enhancer-Binding Proteins
Concept	Fas Ligand Protein
Concept	JNK Mitogen-Activated Protein Kinases
Concept	Pore Forming Cytotoxic Proteins
Concept	I-kappa B Proteins
Concept	Adaptor Proteins, Vesicular Transport
Concept	Protein Conformation
Concept	Apoptosis Regulatory Proteins
Concept	Nucleocapsid Proteins
Concept	Armadillo Domain Proteins
Concept	HMGB1 Protein
Concept	GTPase-Activating Proteins
Concept	RNA-Binding Proteins
Concept	Receptor-Interacting Protein Serine-Threonine Kinase 2
Concept	CARD Signaling Adaptor Proteins
Academic Article	Synthetic oligodeoxynucleotides containing suppressive TTAGGG motifs inhibit AIM2 inflammasome activation.
Academic Article	Cutting edge: Mycobacterium tuberculosis but not nonvirulent mycobacteria inhibits IFN-? and AIM2 inflammasome-dependent IL-1? production via its ESX-1 secretion system.
Academic Article	Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome.
Academic Article	Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome.
Academic Article	STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease.
Academic Article	Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1? production.
Academic Article	Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.
Academic Article	Recognition of cytosolic DNA by cGAS and other STING-dependent sensors.
Academic Article	Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection.
Academic Article	Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
Academic Article	Rift Valley fever virus infection induces activation of the NLRP3 inflammasome.
Academic Article	Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
Academic Article	TRIF signaling is essential for TLR4-driven IgE class switching.
Academic Article	NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING.
Academic Article	Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.
Academic Article	Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.
Academic Article	Post-transcriptional regulation of gene expression in innate immunity.
Academic Article	Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome.
Academic Article	TRIM13 is a negative regulator of MDA5-mediated type I interferon production.
Academic Article	RNA and ?-hemolysin of group B Streptococcus induce interleukin-1? (IL-1?) by activating NLRP3 inflammasomes in mouse macrophages.
Academic Article	TRIL is involved in cytokine production in the brain following Escherichia coli infection.
Academic Article	Interferon ?-inducible protein (IFI) 16 transcriptionally regulates type i interferons and other interferon-stimulated genes and controls the interferon response to both DNA and RNA viruses.
Academic Article	Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1? production in response to ?-glucans and the fungal pathogen, Candida albicans.
Academic Article	IKKa negatively regulates ASC-dependent inflammasome activation.
Academic Article	STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.
Academic Article	Identification of Aim2 as a sensor for DNA vaccines.
Academic Article	Cutting edge: AIM2 and endosomal TLRs differentially regulate arthritis and autoantibody production in DNase II-deficient mice.
Academic Article	A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling.
Academic Article	Suppression of systemic autoimmunity by the innate immune adaptor STING.
Academic Article	Involvement of Nod2 in the innate immune response elicited by malarial pigment hemozoin.
Academic Article	GBPs take AIM at Francisella.
Academic Article	Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3.
Academic Article	Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease.
Academic Article	Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage.
Academic Article	An unexpected role for RNA-sensing toll-like receptors in a murine model of DNA accrual.
Academic Article	Gadolinium-based compounds induce NLRP3-dependent IL-1? production and peritoneal inflammation.
Academic Article	Cutting Edge: DNA in the Lung Microenvironment during Influenza Virus Infection Tempers Inflammation by Engaging the DNA Sensor AIM2.
Academic Article	A cGAS-Independent STING/IRF7 Pathway Mediates the Immunogenicity of DNA Vaccines.
Academic Article	Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II-/-IFNaR-/- Mice.
Academic Article	The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons.
Academic Article	Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4.
Academic Article	A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In?Vivo Infection.
Academic Article	Group B Streptococcus Degrades Cyclic-di-AMP to Modulate STING-Dependent Type I Interferon Production.
Academic Article	Control of the innate immune response by the mevalonate pathway.
Academic Article	Cutting Edge: Novel Tmem173 Allele Reveals Importance of STING N Terminus in Trafficking and Type I IFN Production.
Academic Article	Taking the STING out of TLR-driven autoimmune diseases: good, bad, or indifferent?
Academic Article	Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes.
Academic Article	miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN).
Academic Article	Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-? Synthesis Induced by Lipopolysaccharide.
Academic Article	The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury.
Academic Article	Cyclic GMP-AMP Synthase Is the Cytosolic Sensor of Plasmodium falciparum Genomic DNA and Activates Type I IFN in Malaria.
Academic Article	Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation.
Academic Article	Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis.
Academic Article	Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.
Academic Article	The PYHIN Protein p205 Regulates the Inflammasome by Controlling Asc Expression.
Academic Article	Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
Academic Article	CNBP controls IL-12 gene transcription and Th1 immunity.
Academic Article	Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS.
Academic Article	Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM.
Academic Article	Activation of Stimulator of Interferon Genes (STING) and Sj?gren Syndrome.
Academic Article	DNA sensing by the cGAS-STING pathway in health and disease.
Academic Article	Gasdermins and their role in immunity and inflammation.
Academic Article	A Mitochondrial Micropeptide Is Required for Activation of the Nlrp3 Inflammasome.
Academic Article	Assembling the Inflammasome, Piece by Piece.
Academic Article	Constitutive interferon signaling maintains critical threshold of MLKL expression to license necroptosis.
Academic Article	Long non-coding RNAs in antiviral immunity.
Academic Article	STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1? expression.
Academic Article	Succination inactivates gasdermin D and blocks pyroptosis.
Academic Article	HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation.
Academic Article	Direct Binding to NLRP3 Pyrin Domain as a Novel Strategy to Prevent NLRP3-Driven Inflammation and Gouty Arthritis.
Academic Article	The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans.
Academic Article	cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE.
Academic Article	Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells.
Academic Article	Cellular nucleic acid-binding protein is essential for type I interferon-mediated immunity to RNA virus infection.
Academic Article	AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma.
Academic Article	Igniting the firestorm: The inflammasome in autoinflammatory syndromes.
Academic Article	A genetic screen in macrophages identifies new regulators of IFN?-inducible MHCII that contribute to T cell activation.
Concept	NLR Family, Pyrin Domain-Containing 3 Protein
Concept	NLR Proteins
Concept	Tripartite Motif Proteins
Concept	Suppressor of Cytokine Signaling 1 Protein
Concept	DEAD Box Protein 58
Concept	Prion Proteins
Concept	Interleukin-1 Receptor-Like 1 Protein
Concept	Tumor Necrosis Factor alpha-Induced Protein 3
Concept	Myelin and Lymphocyte-Associated Proteolipid Proteins
Academic Article	Radioresistant cells initiate lymphocyte-dependent lung inflammation and IFN?-dependent mortality in STING gain-of-function mice.
Academic Article	Dual Inhibitors of Main Protease (MPro) and Cathepsin L as Potent Antivirals against SARS-CoV2.
Academic Article	Hold your horses! Reining in your fastest pores with caspase-7.
Academic Article	Activation of the NLRP1 inflammasome in human keratinocytes by the dsDNA mimetic poly(dA:dT).
Academic Article	TBK1 inhibition unleashes RIPK1, resensitizing tumors to immunotherapy.
Academic Article	MLKL-Driven Inflammasome Activation and Caspase-8 Mediate Inflammatory Cell Death in Influenza A Virus Infection.
Academic Article	Targeting STING oligomerization with small-molecule inhibitors.
Academic Article	STING channels its proton power.
Academic Article	Cellular nucleic acid-binding protein restricts SARS-CoV-2 by regulating interferon and disrupting RNA-protein condensates.
Academic Article	Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration.
Academic Article	Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer.
Academic Article	Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair.
Academic Article	A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control.
Academic Article	CRISPR editing of candidate host factors that impact influenza A virus infection.
Academic Article	Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance.

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GTP Binding Proteins