Item Type | Name |
Academic Article
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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
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Academic Article
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The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
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Academic Article
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Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination.
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Academic Article
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Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5.
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Academic Article
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A novel IFN regulatory factor 3-dependent pathway activated by trypanosomes triggers IFN-beta in macrophages and fibroblasts.
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Academic Article
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TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA.
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Academic Article
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NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis.
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Academic Article
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Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling.
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Academic Article
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Differential gene expression downstream of Toll-like receptors (TLRs): role of c-Src and activating transcription factor 3 (ATF3).
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Academic Article
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Catenin' on to nucleic acid sensing.
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Academic Article
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Induction and inhibition of type I interferon responses by distinct components of lymphocytic choriomeningitis virus.
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Academic Article
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Role of interferon regulatory factor 7 in T cell responses during acute lymphocytic choriomeningitis virus infection.
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Academic Article
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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
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Academic Article
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IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts.
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Academic Article
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Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors.
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Academic Article
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The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades.
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Academic Article
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Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence.
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Academic Article
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Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation.
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Academic Article
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Toll-like receptor-dependent and -independent viperin gene expression and counter-regulation by PRDI-binding factor-1/BLIMP1.
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Academic Article
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The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis.
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Academic Article
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Absence of MyD88 results in enhanced TLR3-dependent phosphorylation of IRF3 and increased IFN-? and RANTES production.
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Academic Article
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Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome.
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Academic Article
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Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway.
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Academic Article
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Resistance to HSV-1 infection in the epithelium resides with the novel innate sensor, IFI-16.
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Academic Article
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Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid.
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Concept
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Interferon-Stimulated Gene Factor 3
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Concept
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Interferon Regulatory Factor-7
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Concept
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Interferon Regulatory Factor-3
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Concept
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Interferon Regulatory Factor-1
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Academic Article
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STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease.
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Academic Article
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Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection.
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Academic Article
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TRIM13 is a negative regulator of MDA5-mediated type I interferon production.
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Academic Article
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STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.
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Academic Article
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A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling.
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Academic Article
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Suppression of systemic autoimmunity by the innate immune adaptor STING.
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Academic Article
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GBPs take AIM at Francisella.
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Academic Article
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A cGAS-Independent STING/IRF7 Pathway Mediates the Immunogenicity of DNA Vaccines.
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Academic Article
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Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes.
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Academic Article
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Cyclic GMP-AMP Synthase Is the Cytosolic Sensor of Plasmodium falciparum Genomic DNA and Activates Type I IFN in Malaria.
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Academic Article
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IRF3 and type I interferons fuel a fatal response to myocardial infarction.
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Academic Article
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Cellular nucleic acid-binding protein is essential for type I interferon-mediated immunity to RNA virus infection.
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