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Fitzgerald, Katherine

One or more keywords matched the following items that are connected to Fitzgerald, Katherine

Item Type	Name
Academic Article	IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
Academic Article	The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
Academic Article	The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3.
Academic Article	Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination.
Academic Article	Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5.
Academic Article	A novel IFN regulatory factor 3-dependent pathway activated by trypanosomes triggers IFN-beta in macrophages and fibroblasts.
Academic Article	TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA.
Academic Article	NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis.
Academic Article	Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling.
Academic Article	Differential gene expression downstream of Toll-like receptors (TLRs): role of c-Src and activating transcription factor 3 (ATF3).
Academic Article	Catenin' on to nucleic acid sensing.
Academic Article	Induction and inhibition of type I interferon responses by distinct components of lymphocytic choriomeningitis virus.
Academic Article	Role of interferon regulatory factor 7 in T cell responses during acute lymphocytic choriomeningitis virus infection.
Academic Article	LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
Academic Article	IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts.
Academic Article	Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors.
Academic Article	Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence.
Academic Article	Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation.
Academic Article	Pin-ning down immune responses to RNA viruses.
Academic Article	The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis.
Academic Article	Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role in the innate antiviral response.
Academic Article	Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality.
Academic Article	Absence of MyD88 results in enhanced TLR3-dependent phosphorylation of IRF3 and increased IFN-? and RANTES production.
Academic Article	Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway.
Academic Article	Resistance to HSV-1 infection in the epithelium resides with the novel innate sensor, IFI-16.
Concept	Interferon Regulatory Factor-7
Concept	Interferon Regulatory Factor-3
Concept	Interferon Regulatory Factor-1
Academic Article	STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease.
Academic Article	Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection.
Academic Article	TRIM13 is a negative regulator of MDA5-mediated type I interferon production.
Academic Article	A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling.
Academic Article	GBPs take AIM at Francisella.
Academic Article	A cGAS-Independent STING/IRF7 Pathway Mediates the Immunogenicity of DNA Vaccines.
Academic Article	Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes.
Academic Article	IRF3 and type I interferons fuel a fatal response to myocardial infarction.
Academic Article	Cellular nucleic acid-binding protein is essential for type I interferon-mediated immunity to RNA virus infection.

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Interferon Regulatory Factor 3