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Search Results to Katherine A Fitzgerald PhD

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One or more keywords matched the following items that are connected to Fitzgerald, Katherine

Item TypeName
Academic Article Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.
Academic Article Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction.
Academic Article Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response.
Academic Article DUBbing down innate immunity.
Academic Article The role of the interleukin-1/Toll-like receptor superfamily in inflammation and host defence.
Academic Article Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.
Academic Article Immunology. The shape of things to come.
Academic Article Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination.
Academic Article An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans.
Academic Article A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.
Academic Article Integr-ating IL-1 alpha in antiviral host defenses.
Academic Article Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling.
Academic Article Differential gene expression downstream of Toll-like receptors (TLRs): role of c-Src and activating transcription factor 3 (ATF3).
Academic Article TLR4 is a negative regulator in noninfectious lung inflammation.
Academic Article Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome.
Academic Article Inflammasomes and anti-viral immunity.
Academic Article Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation.
Academic Article Activation of autophagy by inflammatory signals limits IL-1ß production by targeting ubiquitinated inflammasomes for destruction.
Academic Article Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Academic Article Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1ß.
Academic Article The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.
Academic Article CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Academic Article The Toll-IL-1 receptor adaptor family grows to five members.
Academic Article TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression.
Academic Article Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors.
Academic Article Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence.
Academic Article Dengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion.
Academic Article Sorting out Toll signals.
Academic Article Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling.
Academic Article Toll-like receptor-dependent and -independent viperin gene expression and counter-regulation by PRDI-binding factor-1/BLIMP1.
Academic Article NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.
Academic Article Role of MyD88 in route-dependent susceptibility to vesicular stomatitis virus infection.
Academic Article Salmonella-induced SipB-independent cell death requires Toll-like receptor-4 signalling via the adapter proteins Tram and Trif.
Academic Article Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.
Academic Article NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Academic Article Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
Academic Article Regulation of lipopolysaccharide-induced translation of tumor necrosis factor-alpha by the toll-like receptor 4 adaptor protein TRAM.
Academic Article Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice.
Academic Article Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway.
Academic Article The NLRP12 inflammasome recognizes Yersinia pestis.
Academic Article NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1ß and neuronal toxicity.
Academic Article 5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential.
Academic Article Cutting edge: FAS (CD95) mediates noncanonical IL-1ß and IL-18 maturation via caspase-8 in an RIP3-independent manner.
Academic Article Defective pro-IL-1ß responses in macrophages from aged mice.
Academic Article Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins.
Academic Article Interferon-? and granulocyte/monocyte colony-stimulating factor production by natural killer cells involves different signaling pathways and the adaptor stimulator of interferon genes (STING).
Academic Article An alternative pathway of T-cell activation: a functional role for the 50 kd T11 sheep erythrocyte receptor protein.
Academic Article The human T cell receptor: appearance in ontogeny and biochemical relationship of alpha and beta subunits on IL-2 dependent clones and T cell tumors.
Concept Receptors, Interleukin-1
Concept Interleukin-1alpha
Concept Interleukin-15
Concept Interleukin-1 Receptor-Associated Kinases
Concept Interleukin-2
Concept Interleukin-1
Concept Interleukin 1 Receptor Antagonist Protein
Concept Interleukin-17
Concept Interleukin-1beta
Concept Interleukin-8
Concept Interleukin-4
Concept Interleukin-6
Concept Receptors, Interleukin
Concept Interleukin-18
Concept Interleukin-12
Academic Article Cutting edge: Mycobacterium tuberculosis but not nonvirulent mycobacteria inhibits IFN-ß and AIM2 inflammasome-dependent IL-1ß production via its ESX-1 secretion system.
Academic Article Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome.
Academic Article Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome.
Academic Article Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1ß production.
Academic Article Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.
Academic Article Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
Academic Article Rift Valley fever virus infection induces activation of the NLRP3 inflammasome.
Academic Article Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
Academic Article TRIF signaling is essential for TLR4-driven IgE class switching.
Academic Article Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.
Academic Article Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome.
Academic Article 3-Hydroxyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin)-induced 28-kDa interleukin-1ß interferes with mature IL-1ß signaling.
Academic Article RNA and ß-hemolysin of group B Streptococcus induce interleukin-1ß (IL-1ß) by activating NLRP3 inflammasomes in mouse macrophages.
Academic Article TRIL is involved in cytokine production in the brain following Escherichia coli infection.
Academic Article Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1ß production in response to ß-glucans and the fungal pathogen, Candida albicans.
Academic Article Identification of Aim2 as a sensor for DNA vaccines.
Academic Article A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling.
Academic Article Mechanisms of inflammasome activation: recent advances and novel insights.
Academic Article Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease.
Academic Article Cutting Edge: A Natural Antisense Transcript, AS-IL1a, Controls Inducible Transcription of the Proinflammatory Cytokine IL-1a.
Academic Article Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage.
Academic Article Gadolinium-based compounds induce NLRP3-dependent IL-1ß production and peritoneal inflammation.
Academic Article A Dectin-1-Caspase-8 Pathway Licenses Canonical Caspase-1 Inflammasome Activation and Interleukin-1ß Release in Response to a Pathogenic Fungus.
Academic Article CNBP controls IL-12 gene transcription and Th1 immunity.
Academic Article Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM.

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  • Interleukin 1