| Item Type | Name |
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Academic Article
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Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.
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Academic Article
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Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction.
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Academic Article
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Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response.
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Academic Article
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DUBbing down innate immunity.
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Academic Article
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The role of the interleukin-1/Toll-like receptor superfamily in inflammation and host defence.
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Academic Article
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Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.
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Academic Article
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Immunology. The shape of things to come.
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Academic Article
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Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination.
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Academic Article
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An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans.
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Academic Article
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A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.
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Academic Article
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Integr-ating IL-1 alpha in antiviral host defenses.
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Academic Article
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Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling.
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Academic Article
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Differential gene expression downstream of Toll-like receptors (TLRs): role of c-Src and activating transcription factor 3 (ATF3).
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Academic Article
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TLR4 is a negative regulator in noninfectious lung inflammation.
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Academic Article
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Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome.
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Academic Article
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Inflammasomes and anti-viral immunity.
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Academic Article
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Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation.
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Academic Article
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Activation of autophagy by inflammatory signals limits IL-1? production by targeting ubiquitinated inflammasomes for destruction.
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Academic Article
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Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
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Academic Article
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Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1?.
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Academic Article
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The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.
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Academic Article
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CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
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Academic Article
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The Toll-IL-1 receptor adaptor family grows to five members.
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Academic Article
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TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression.
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Academic Article
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Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors.
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Academic Article
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Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence.
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Academic Article
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Dengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion.
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Academic Article
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Sorting out Toll signals.
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Academic Article
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Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling.
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Academic Article
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Toll-like receptor-dependent and -independent viperin gene expression and counter-regulation by PRDI-binding factor-1/BLIMP1.
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Academic Article
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NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.
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Academic Article
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Role of MyD88 in route-dependent susceptibility to vesicular stomatitis virus infection.
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Academic Article
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Salmonella-induced SipB-independent cell death requires Toll-like receptor-4 signalling via the adapter proteins Tram and Trif.
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Academic Article
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Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.
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Academic Article
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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
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Academic Article
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Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
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Academic Article
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Regulation of lipopolysaccharide-induced translation of tumor necrosis factor-alpha by the toll-like receptor 4 adaptor protein TRAM.
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Academic Article
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Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice.
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Academic Article
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Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway.
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Academic Article
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The NLRP12 inflammasome recognizes Yersinia pestis.
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Academic Article
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NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1? and neuronal toxicity.
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Academic Article
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5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential.
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Academic Article
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Cutting edge: FAS (CD95) mediates noncanonical IL-1? and IL-18 maturation via caspase-8 in an RIP3-independent manner.
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Academic Article
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Defective pro-IL-1? responses in macrophages from aged mice.
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Academic Article
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Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins.
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Academic Article
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Interferon-? and granulocyte/monocyte colony-stimulating factor production by natural killer cells involves different signaling pathways and the adaptor stimulator of interferon genes (STING).
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Academic Article
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An alternative pathway of T-cell activation: a functional role for the 50 kd T11 sheep erythrocyte receptor protein.
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Academic Article
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The human T cell receptor: appearance in ontogeny and biochemical relationship of alpha and beta subunits on IL-2 dependent clones and T cell tumors.
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Concept
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Receptors, Interleukin-1
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Concept
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Interleukin-1alpha
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Concept
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Interleukin-15
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Concept
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Interleukin-1 Receptor-Associated Kinases
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Concept
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Interleukin-2
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Concept
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Interleukin-1
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Concept
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Interleukin 1 Receptor Antagonist Protein
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Concept
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Interleukin-17
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Concept
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Interleukin-1beta
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Concept
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Interleukin-8
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Concept
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Interleukin-12 Subunit p40
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Concept
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Interleukin-4
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Concept
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Interleukin-6
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Concept
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Receptors, Interleukin
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Concept
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Interleukin-18
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Concept
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Interleukin-12
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Academic Article
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Cutting edge: Mycobacterium tuberculosis but not nonvirulent mycobacteria inhibits IFN-? and AIM2 inflammasome-dependent IL-1? production via its ESX-1 secretion system.
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Academic Article
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Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome.
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Academic Article
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Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome.
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Academic Article
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Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1? production.
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Academic Article
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Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.
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Academic Article
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Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
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Academic Article
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Rift Valley fever virus infection induces activation of the NLRP3 inflammasome.
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Academic Article
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Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
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Academic Article
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TRIF signaling is essential for TLR4-driven IgE class switching.
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Academic Article
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Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.
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Academic Article
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Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome.
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Academic Article
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3-Hydroxyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin)-induced 28-kDa interleukin-1? interferes with mature IL-1? signaling.
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Academic Article
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RNA and ?-hemolysin of group B Streptococcus induce interleukin-1? (IL-1?) by activating NLRP3 inflammasomes in mouse macrophages.
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Academic Article
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TRIL is involved in cytokine production in the brain following Escherichia coli infection.
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Academic Article
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Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1? production in response to ?-glucans and the fungal pathogen, Candida albicans.
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Academic Article
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Identification of Aim2 as a sensor for DNA vaccines.
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Academic Article
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A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling.
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Academic Article
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Mechanisms of inflammasome activation: recent advances and novel insights.
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Academic Article
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Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease.
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Academic Article
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Cutting Edge: A Natural Antisense Transcript, AS-IL1a, Controls Inducible Transcription of the Proinflammatory Cytokine IL-1a.
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Academic Article
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Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage.
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Academic Article
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Gadolinium-based compounds induce NLRP3-dependent IL-1? production and peritoneal inflammation.
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Academic Article
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Control of the innate immune response by the mevalonate pathway.
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Academic Article
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miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN).
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Academic Article
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Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis.
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Academic Article
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A Dectin-1-Caspase-8 Pathway Licenses Canonical Caspase-1 Inflammasome Activation and Interleukin-1? Release in Response to a Pathogenic Fungus.
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Academic Article
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CNBP controls IL-12 gene transcription and Th1 immunity.
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Academic Article
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Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM.
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Academic Article
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Assembling the Inflammasome, Piece by Piece.
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Academic Article
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STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1? expression.
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Academic Article
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Caspase-8 mediates inflammation and disease in rodent malaria.
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Academic Article
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Direct Binding to NLRP3 Pyrin Domain as a Novel Strategy to Prevent NLRP3-Driven Inflammation and Gouty Arthritis.
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Academic Article
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Igniting the firestorm: The inflammasome in autoinflammatory syndromes.
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Concept
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Interleukin-1 Receptor-Like 1 Protein
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Academic Article
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Lymphocyte crosstalk is required for monocyte-intrinsic trained immunity to Plasmodium falciparum.
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Academic Article
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Activation of the NLRP1 inflammasome in human keratinocytes by the dsDNA mimetic poly(dA:dT).
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Academic Article
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Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.
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Academic Article
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The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection.
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