Item Type | Name |
Academic Article
|
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.
|
Academic Article
|
Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction.
|
Academic Article
|
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
|
Academic Article
|
Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response.
|
Academic Article
|
DUBbing down innate immunity.
|
Academic Article
|
The role of the interleukin-1/Toll-like receptor superfamily in inflammation and host defence.
|
Academic Article
|
Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.
|
Academic Article
|
Immunology. The shape of things to come.
|
Academic Article
|
Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination.
|
Academic Article
|
A novel IFN regulatory factor 3-dependent pathway activated by trypanosomes triggers IFN-beta in macrophages and fibroblasts.
|
Academic Article
|
An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans.
|
Academic Article
|
A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.
|
Academic Article
|
Integr-ating IL-1 alpha in antiviral host defenses.
|
Academic Article
|
Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling.
|
Academic Article
|
Differential gene expression downstream of Toll-like receptors (TLRs): role of c-Src and activating transcription factor 3 (ATF3).
|
Academic Article
|
TLR4 is a negative regulator in noninfectious lung inflammation.
|
Academic Article
|
Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome.
|
Academic Article
|
Inflammasomes and anti-viral immunity.
|
Academic Article
|
Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation.
|
Academic Article
|
Activation of autophagy by inflammatory signals limits IL-1? production by targeting ubiquitinated inflammasomes for destruction.
|
Academic Article
|
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
|
Academic Article
|
Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1?.
|
Academic Article
|
The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.
|
Academic Article
|
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
|
Academic Article
|
The Toll-IL-1 receptor adaptor family grows to five members.
|
Academic Article
|
IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts.
|
Academic Article
|
TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression.
|
Academic Article
|
Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors.
|
Academic Article
|
Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence.
|
Academic Article
|
Dengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion.
|
Academic Article
|
Sorting out Toll signals.
|
Academic Article
|
Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling.
|
Academic Article
|
Toll-like receptor-dependent and -independent viperin gene expression and counter-regulation by PRDI-binding factor-1/BLIMP1.
|
Academic Article
|
NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.
|
Academic Article
|
Role of MyD88 in route-dependent susceptibility to vesicular stomatitis virus infection.
|
Academic Article
|
Salmonella-induced SipB-independent cell death requires Toll-like receptor-4 signalling via the adapter proteins Tram and Trif.
|
Academic Article
|
Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.
|
Academic Article
|
Cell type-specific recognition of human metapneumoviruses (HMPVs) by retinoic acid-inducible gene I (RIG-I) and TLR7 and viral interference of RIG-I ligand recognition by HMPV-B1 phosphoprotein.
|
Academic Article
|
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
|
Academic Article
|
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
|
Academic Article
|
Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus.
|
Academic Article
|
Absence of MyD88 results in enhanced TLR3-dependent phosphorylation of IRF3 and increased IFN-? and RANTES production.
|
Academic Article
|
Regulation of lipopolysaccharide-induced translation of tumor necrosis factor-alpha by the toll-like receptor 4 adaptor protein TRAM.
|
Academic Article
|
Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice.
|
Academic Article
|
Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway.
|
Academic Article
|
The NLRP12 inflammasome recognizes Yersinia pestis.
|
Academic Article
|
NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1? and neuronal toxicity.
|
Academic Article
|
5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential.
|
Academic Article
|
Cutting edge: FAS (CD95) mediates noncanonical IL-1? and IL-18 maturation via caspase-8 in an RIP3-independent manner.
|
Academic Article
|
Defective pro-IL-1? responses in macrophages from aged mice.
|
Academic Article
|
Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins.
|
Academic Article
|
RNA helicase signaling is critical for type i interferon production and protection against Rift Valley fever virus during mucosal challenge.
|
Academic Article
|
Interferon-? and granulocyte/monocyte colony-stimulating factor production by natural killer cells involves different signaling pathways and the adaptor stimulator of interferon genes (STING).
|
Academic Article
|
Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid.
|
Academic Article
|
An alternative pathway of T-cell activation: a functional role for the 50 kd T11 sheep erythrocyte receptor protein.
|
Academic Article
|
The human T cell receptor: appearance in ontogeny and biochemical relationship of alpha and beta subunits on IL-2 dependent clones and T cell tumors.
|
Concept
|
Receptors, Interleukin-1
|
Concept
|
Interferon-beta
|
Concept
|
Interleukin-1alpha
|
Concept
|
Interleukin-15
|
Concept
|
Interleukin-1 Receptor-Associated Kinases
|
Concept
|
Interleukin-2
|
Concept
|
Interleukin-1
|
Concept
|
Interleukin 1 Receptor Antagonist Protein
|
Concept
|
Interleukin-17
|
Concept
|
Interleukin-1beta
|
Concept
|
Interleukin-8
|
Concept
|
Interleukin-12 Subunit p40
|
Concept
|
Interleukin-4
|
Concept
|
Interleukin-6
|
Concept
|
Receptors, Interleukin
|
Concept
|
Interleukin-18
|
Concept
|
Interleukin-12
|
Academic Article
|
Cutting edge: Mycobacterium tuberculosis but not nonvirulent mycobacteria inhibits IFN-? and AIM2 inflammasome-dependent IL-1? production via its ESX-1 secretion system.
|
Academic Article
|
Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome.
|
Academic Article
|
Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome.
|
Academic Article
|
Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1? production.
|
Academic Article
|
Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.
|
Academic Article
|
Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
|
Academic Article
|
Rift Valley fever virus infection induces activation of the NLRP3 inflammasome.
|
Academic Article
|
Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
|
Academic Article
|
TRIF signaling is essential for TLR4-driven IgE class switching.
|
Academic Article
|
Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.
|
Academic Article
|
Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome.
|
Academic Article
|
TRIM13 is a negative regulator of MDA5-mediated type I interferon production.
|
Academic Article
|
3-Hydroxyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin)-induced 28-kDa interleukin-1? interferes with mature IL-1? signaling.
|
Academic Article
|
RNA and ?-hemolysin of group B Streptococcus induce interleukin-1? (IL-1?) by activating NLRP3 inflammasomes in mouse macrophages.
|
Academic Article
|
TRIL is involved in cytokine production in the brain following Escherichia coli infection.
|
Academic Article
|
Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1? production in response to ?-glucans and the fungal pathogen, Candida albicans.
|
Academic Article
|
STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.
|
Academic Article
|
Identification of Aim2 as a sensor for DNA vaccines.
|
Academic Article
|
A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling.
|
Academic Article
|
Mechanisms of inflammasome activation: recent advances and novel insights.
|
Academic Article
|
Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease.
|
Academic Article
|
Cutting Edge: A Natural Antisense Transcript, AS-IL1a, Controls Inducible Transcription of the Proinflammatory Cytokine IL-1a.
|
Academic Article
|
Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage.
|
Academic Article
|
Gadolinium-based compounds induce NLRP3-dependent IL-1? production and peritoneal inflammation.
|
Academic Article
|
Control of the innate immune response by the mevalonate pathway.
|
Academic Article
|
miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN).
|
Academic Article
|
Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-? Synthesis Induced by Lipopolysaccharide.
|
Academic Article
|
Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis.
|
Academic Article
|
A Dectin-1-Caspase-8 Pathway Licenses Canonical Caspase-1 Inflammasome Activation and Interleukin-1? Release in Response to a Pathogenic Fungus.
|
Academic Article
|
CNBP controls IL-12 gene transcription and Th1 immunity.
|
Academic Article
|
Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM.
|
Academic Article
|
Assembling the Inflammasome, Piece by Piece.
|
Academic Article
|
Constitutive interferon signaling maintains critical threshold of MLKL expression to license necroptosis.
|
Academic Article
|
STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1? expression.
|
Academic Article
|
Caspase-8 mediates inflammation and disease in rodent malaria.
|
Academic Article
|
Direct Binding to NLRP3 Pyrin Domain as a Novel Strategy to Prevent NLRP3-Driven Inflammation and Gouty Arthritis.
|
Academic Article
|
Igniting the firestorm: The inflammasome in autoinflammatory syndromes.
|
Concept
|
Interleukin-1 Receptor-Like 1 Protein
|
Academic Article
|
Lymphocyte crosstalk is required for monocyte-intrinsic trained immunity to Plasmodium falciparum.
|
Academic Article
|
Activation of the NLRP1 inflammasome in human keratinocytes by the dsDNA mimetic poly(dA:dT).
|
Academic Article
|
Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.
|
Academic Article
|
The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection.
|