Header Logo

Search Result Details

This page shows the details of why an item matched the keywords from your search.
One or more keywords matched the following items that are connected to Fitzgerald, Katherine
Item TypeName
Academic Article Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.
Academic Article Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.
Academic Article Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Academic Article TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA.
Academic Article Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.
Academic Article Role of p38 and early growth response factor 1 in the macrophage response to group B streptococcus.
Academic Article An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans.
Academic Article NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis.
Academic Article Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling.
Academic Article TLR4 is a negative regulator in noninfectious lung inflammation.
Academic Article Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation.
Academic Article A novel role for the NLRC4 inflammasome in mucosal defenses against the fungal pathogen Candida albicans.
Academic Article Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Academic Article DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation.
Academic Article Role of interferon regulatory factor 7 in T cell responses during acute lymphocytic choriomeningitis virus infection.
Academic Article Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1?.
Academic Article The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.
Academic Article Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function.
Academic Article CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Academic Article LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
Academic Article TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Academic Article Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1.
Academic Article The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades.
Academic Article Toll-like receptor-dependent and -independent viperin gene expression and counter-regulation by PRDI-binding factor-1/BLIMP1.
Academic Article Role of MyD88 in route-dependent susceptibility to vesicular stomatitis virus infection.
Academic Article Salmonella-induced SipB-independent cell death requires Toll-like receptor-4 signalling via the adapter proteins Tram and Trif.
Academic Article The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis.
Academic Article Cell type-specific recognition of human metapneumoviruses (HMPVs) by retinoic acid-inducible gene I (RIG-I) and TLR7 and viral interference of RIG-I ligand recognition by HMPV-B1 phosphoprotein.
Academic Article Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome.
Academic Article The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.
Academic Article NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Academic Article Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
Academic Article Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling.
Academic Article Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.
Academic Article Absence of MyD88 results in enhanced TLR3-dependent phosphorylation of IRF3 and increased IFN-? and RANTES production.
Academic Article Regulation of lipopolysaccharide-induced translation of tumor necrosis factor-alpha by the toll-like receptor 4 adaptor protein TRAM.
Academic Article Streptococcus pneumoniae DNA initiates type I interferon signaling in the respiratory tract.
Academic Article Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice.
Academic Article Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway.
Academic Article The NLRP12 inflammasome recognizes Yersinia pestis.
Academic Article NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1? and neuronal toxicity.
Academic Article Cutting edge: FAS (CD95) mediates noncanonical IL-1? and IL-18 maturation via caspase-8 in an RIP3-independent manner.
Academic Article Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins.
Academic Article RNA helicase signaling is critical for type i interferon production and protection against Rift Valley fever virus during mucosal challenge.
Academic Article Overexpression of membrane-bound fas ligand (CD95L) exacerbates autoimmune disease and renal pathology in pristane-induced lupus.
Concept Mice, Inbred BALB C
Concept Mice, Inbred C3H
Concept Mice, Inbred C57BL
Academic Article Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome.
Academic Article Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome.
Academic Article Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1? production.
Academic Article Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.
Academic Article Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection.
Academic Article Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
Academic Article Rift Valley fever virus infection induces activation of the NLRP3 inflammasome.
Academic Article TRIF signaling is essential for TLR4-driven IgE class switching.
Academic Article Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.
Academic Article Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome.
Academic Article TRIM13 is a negative regulator of MDA5-mediated type I interferon production.
Academic Article 3-Hydroxyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin)-induced 28-kDa interleukin-1? interferes with mature IL-1? signaling.
Academic Article TRIL is involved in cytokine production in the brain following Escherichia coli infection.
Academic Article STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.
Academic Article Involvement of Nod2 in the innate immune response elicited by malarial pigment hemozoin.
Academic Article Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease.
Academic Article Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage.
Academic Article Gadolinium-based compounds induce NLRP3-dependent IL-1? production and peritoneal inflammation.
Academic Article Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice.
Academic Article Cutting Edge: DNA in the Lung Microenvironment during Influenza Virus Infection Tempers Inflammation by Engaging the DNA Sensor AIM2.
Academic Article A cGAS-Independent STING/IRF7 Pathway Mediates the Immunogenicity of DNA Vaccines.
Academic Article Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection.
Academic Article Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II-/-IFNaR-/- Mice.
Academic Article A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation.
Academic Article A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In?Vivo Infection.
Academic Article Control of the innate immune response by the mevalonate pathway.
Academic Article Cutting Edge: Novel Tmem173 Allele Reveals Importance of STING N Terminus in Trafficking and Type I IFN Production.
Academic Article Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes.
Academic Article The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury.
Academic Article IRF3 and type I interferons fuel a fatal response to myocardial infarction.
Academic Article Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation.
Academic Article Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
Academic Article A Dectin-1-Caspase-8 Pathway Licenses Canonical Caspase-1 Inflammasome Activation and Interleukin-1? Release in Response to a Pathogenic Fungus.
Academic Article Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2.
Academic Article Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS.
Academic Article Activation of Stimulator of Interferon Genes (STING) and Sj?gren Syndrome.
Academic Article Long Non-coding RNA LincRNA-EPS Inhibits Host Defense Against Listeria monocytogenes Infection.
Academic Article Constitutive interferon signaling maintains critical threshold of MLKL expression to license necroptosis.
Academic Article STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1? expression.
Academic Article TLR2 Dimerization Blockade Allows Generation of Homeostatic Intestinal Macrophages under Acute Colitis Challenge.
Academic Article Succination inactivates gasdermin D and blocks pyroptosis.
Academic Article Caspase-8 mediates inflammation and disease in rodent malaria.
Academic Article HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation.
Academic Article Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells.
Academic Article Cellular nucleic acid-binding protein is essential for type I interferon-mediated immunity to RNA virus infection.
Academic Article AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma.
Academic Article A genetic screen in macrophages identifies new regulators of IFN?-inducible MHCII that contribute to T cell activation.
Academic Article Epithelial HNF4A shapes the intraepithelial lymphocyte compartment via direct regulation of immune signaling molecules.
Academic Article STING-dependent interferon signatures restrict osteoclast differentiation and bone loss in mice.
Search Criteria
  • Mice Inbred A