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Recognition of cytosolic DNA by cGAS and other STING-dependent sensors.
STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.
A cGAS-Independent STING/IRF7 Pathway Mediates the Immunogenicity of DNA Vaccines.
The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons.
Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4.
Cyclic GMP-AMP Synthase Is the Cytosolic Sensor of Plasmodium falciparum Genomic DNA and Activates Type I IFN in Malaria.
Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS.
cGAS Micro-Manages Genotoxic Stress.
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration.
DNA sensing by the cGAS-STING pathway in health and disease.
Constitutive interferon signaling maintains critical threshold of MLKL expression to license necroptosis.
Loosening the grip on nuclear cGAS.
cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE.
Type-1 interferon-dependent and -independent mechanisms in cyclic GMP-AMP synthase-stimulator of interferon genes-driven auto-inflammation.
Targeting STING oligomerization with small-molecule inhibitors.
Development of LB244, an Irreversible STING Antagonist.
STING channels its proton power.