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Academic Article
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Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.
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Academic Article
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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
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Academic Article
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The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
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Academic Article
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The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.
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Academic Article
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The role of the interleukin-1/Toll-like receptor superfamily in inflammation and host defence.
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Academic Article
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Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.
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Academic Article
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Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.
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Academic Article
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Immunology. The shape of things to come.
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Academic Article
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Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance.
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Academic Article
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Herpesvirus tegument protein activates NF-kappaB signaling through the TRAF6 adaptor protein.
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Academic Article
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Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens.
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Academic Article
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Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.
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Academic Article
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A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.
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Academic Article
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Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling.
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Academic Article
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Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling.
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Academic Article
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TLR4 is a negative regulator in noninfectious lung inflammation.
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Academic Article
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TLR9 provokes inflammation in response to fetal DNA: mechanism for fetal loss in preterm birth and preeclampsia.
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Academic Article
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DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation.
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Academic Article
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The Toll-IL-1 receptor adaptor family grows to five members.
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Academic Article
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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
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Academic Article
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TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
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Academic Article
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Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1.
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Academic Article
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Endotoxin recognition and signal transduction by the TLR4/MD2-complex.
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Academic Article
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Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence.
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Academic Article
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Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation.
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Academic Article
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Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex.
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Academic Article
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The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.
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Academic Article
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Sorting out Toll signals.
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Academic Article
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Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling.
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Academic Article
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Toll-like receptor-dependent and -independent viperin gene expression and counter-regulation by PRDI-binding factor-1/BLIMP1.
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Academic Article
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NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.
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Academic Article
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Salmonella-induced SipB-independent cell death requires Toll-like receptor-4 signalling via the adapter proteins Tram and Trif.
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Academic Article
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Superior immunogenicity of inactivated whole virus H5N1 influenza vaccine is primarily controlled by Toll-like receptor signalling.
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Academic Article
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Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes.
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Academic Article
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Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.
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Academic Article
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Cell type-specific recognition of human metapneumoviruses (HMPVs) by retinoic acid-inducible gene I (RIG-I) and TLR7 and viral interference of RIG-I ligand recognition by HMPV-B1 phosphoprotein.
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Academic Article
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Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling.
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Academic Article
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Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.
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Academic Article
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Absence of MyD88 results in enhanced TLR3-dependent phosphorylation of IRF3 and increased IFN-? and RANTES production.
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Academic Article
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Regulation of lipopolysaccharide-induced translation of tumor necrosis factor-alpha by the toll-like receptor 4 adaptor protein TRAM.
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Academic Article
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Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice.
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Academic Article
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Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway.
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Academic Article
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Immunology: Lipopolysaccharide sensing on the inside.
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Concept
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Toll-Like Receptor 6
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Concept
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Toll-Like Receptor 4
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Concept
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Toll-Like Receptor 9
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Concept
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Toll-Like Receptor 3
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Concept
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Toll-Like Receptor 2
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Concept
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Toll-Like Receptor 7
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Concept
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Toll-Like Receptor 1
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Concept
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Toll-Like Receptor 8
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Academic Article
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Antiviral autophagy restrictsRift Valley fever virus infection and is conserved from flies to mammals.
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Academic Article
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Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
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Academic Article
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TRIF signaling is essential for TLR4-driven IgE class switching.
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Academic Article
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TRIL is involved in cytokine production in the brain following Escherichia coli infection.
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Academic Article
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A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling.
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Academic Article
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Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3.
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Academic Article
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An unexpected role for RNA-sensing toll-like receptors in a murine model of DNA accrual.
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Academic Article
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Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4.
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Academic Article
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miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN).
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Academic Article
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Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-? Synthesis Induced by Lipopolysaccharide.
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Academic Article
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Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation.
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Academic Article
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STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1? expression.
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Academic Article
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TLR2 Dimerization Blockade Allows Generation of Homeostatic Intestinal Macrophages under Acute Colitis Challenge.
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Academic Article
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Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer.
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