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Academic Article
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CD8+ T lymphocytes are not required for murine resistance to human filarial parasites.
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Academic Article
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Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris.
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Academic Article
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Characteristics of long-term human thyroid peroxidase autoantibody secretion in scid mice transplanted with lymphocytes from patients with autoimmune thyroiditis.
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Academic Article
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Development and progression of psoriasiform dermatitis and systemic lesions in the flaky skin (fsn) mouse mutant.
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Academic Article
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Animal models for immunodeficiency diseases.
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Academic Article
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The molecular bases of spontaneous immunological mutations in the mouse and their homologous human diseases.
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Academic Article
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Brugian infections in the peritoneal cavities of laboratory mice: kinetics of infection and cellular responses.
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Academic Article
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Mutations at the mouse ichthyosis locus are within the lamin B receptor gene: a single gene model for human Pelger-Hu?t anomaly.
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Academic Article
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A new murine model of humoral immuno-deficiency specifically affects class switching to T-independent antigens.
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Academic Article
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Immunity in experimental murine filariasis: roles of T and B cells revisited.
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Academic Article
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Immunological mutants of the mouse.
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Academic Article
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NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells.
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Academic Article
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Targeting gastrin-releasing peptide receptors on small cell lung cancer cells with a bispecific molecule that activates polyclonal T lymphocytes.
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Academic Article
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Role of gamma interferon and interleukin-4 in host defense against the human filarial parasite Brugia malayi.
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Academic Article
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beta2 microglobulin-deficient (B2m(null)) NOD/SCID mice are excellent recipients for studying human stem cell function.
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Academic Article
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Lanceolate hair-J (lahJ): a mouse model for human hair disorders.
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Academic Article
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Inherited mouse mutations as models of human adnexal, cornification, and papulosquamous dermatoses.
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Academic Article
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Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research.
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Academic Article
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Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment.
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Academic Article
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Improved murine model of malaria using Plasmodium falciparum competent strains and non-myelodepleted NOD-scid IL2Rgammanull mice engrafted with human erythrocytes.
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Academic Article
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Dysferlin deficiency and the development of cardiomyopathy in a mouse model of limb-girdle muscular dystrophy 2B.
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Academic Article
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Humanized mouse models to study human diseases.
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Academic Article
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Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent.
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Academic Article
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Humanized mouse model of ovarian cancer recapitulates patient solid tumor progression, ascites formation, and metastasis.
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Academic Article
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Humanized mouse models of HIV-1 latency.
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Academic Article
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Human allograft rejection in humanized mice: a historical perspective.
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Academic Article
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Dystrophin and dysferlin double mutant mice: a novel model for rhabdomyosarcoma.
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Academic Article
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Humanized mouse model used to monitor MUC gene expression in nasal polyps and to preclinically evaluate the efficacy of montelukast in reducing mucus production.
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Academic Article
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Establishment and characterization of a new osteogenic cell line (MOS-J) from a spontaneous C57BL/6J mouse osteosarcoma.
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Academic Article
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Humanized mice for immune system investigation: progress, promise and challenges.
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Academic Article
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Inflammatory dilated cardiomyopathy in Abcg5-deficient mice.
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Academic Article
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Retrotransposon insertion in the T-cell acute lymphocytic leukemia 1 (Tal1) gene is associated with severe renal disease and patchy alopecia in Hairpatches (Hpt) mice.
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Academic Article
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Changes in ovarian tumor cell number, tumor vasculature, and T cell function monitored in vivo using a novel xenograft model.
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Academic Article
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Mouse models of genetic diseases.
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Academic Article
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Evaluation of the mouse mutant "wasted" as an animal model for ataxia telangiectasia. I. Age-dependent and tissue-specific effects.
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Academic Article
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Hairpatches, a single gene mutation characterized by progressive renal disease and alopecia in the mouse. A potential model for a newly described heritable human disorder.
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Academic Article
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Evaluations of wasted mouse fibroblasts and SV-40 transformed human fibroblasts as models of ataxia telangiectasia in vitro.
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Academic Article
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'Wasted', a new mutant of the mouse with abnormalities characteristic to ataxia telangiectasia.
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Academic Article
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Islet-infiltrating lymphocytes from prediabetic NOD mice rapidly transfer diabetes to NOD-scid/scid mice.
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Academic Article
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Anti-CD11b antibody prevents immunopathologic changes in viable moth-eaten bone marrow chimeric mice.
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Academic Article
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Preservation of functioning human thyroid organoids in the scid mouse: 1. System characterization.
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Academic Article
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Epidermal dendritic cell populations in the flaky skin mutant mouse.
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Academic Article
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Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice.
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Academic Article
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Efficient engraftment of primary adult T-cell leukemia cells in newborn NOD/SCID/beta2-microglobulin(null) mice.
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Academic Article
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The immunodeficient scid mouse as a model for human lymphatic filariasis.
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Academic Article
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Accelerated wound healing of alkali-burned corneas in MRL mice is associated with a reduced inflammatory signature.
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Academic Article
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The SCID-hu mouse and thyroid autoimmunity: characterization of human thyroid autoantibody secretion.
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Academic Article
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Humanized mice in translational biomedical research.
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Academic Article
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Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity.
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Academic Article
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A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.
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Academic Article
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Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice.
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Academic Article
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Humanized SCID mouse models for biomedical research.
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Academic Article
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A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function.
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Academic Article
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Human acute leukemia cells injected in NOD/LtSz-scid/IL-2Rgamma null mice generate a faster and more efficient disease compared to other NOD/scid-related strains.
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Academic Article
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T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice.
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Academic Article
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Humanized mice for the study of type 1 diabetes and beta cell function.
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Academic Article
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Effect of DNA-damaging agents on isolated spleen cells and lung fibroblasts from the mouse mutant "wasted," a putative animal model for ataxia-telangiectasia.
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Academic Article
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The mouse mutant "wasted": an animal model for ataxia-telangiectasia.
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Academic Article
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Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice.
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Academic Article
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Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat.
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Academic Article
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The mouse mutation "thrombocytopenia and cardiomyopathy" (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia.
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Academic Article
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Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease.
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Academic Article
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Human nasal polyp microenvironments maintained in a viable and functional state as xenografts in NOD-scid IL2rgamma(null) mice.
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Academic Article
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Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.
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Academic Article
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Hyperglycemia-induced proliferation of adult human beta cells engrafted into spontaneously diabetic immunodeficient NOD-Rag1null IL2r?null Ins2Akita mice.
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Academic Article
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Human peripheral blood CD4 T cell-engrafted non-obese diabetic-scid IL2r?(null) H2-Ab1 (tm1Gru) Tg (human leucocyte antigen D-related 4) mice: a mouse model of human allogeneic graft-versus-host disease.
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Academic Article
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Humanized mice as a preclinical tool for infectious disease and biomedical research.
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Academic Article
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Humanized mice for the study of type 1 and type 2 diabetes.
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Academic Article
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Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice.
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Academic Article
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Humanized mice for the study of infectious diseases.
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Academic Article
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Engraftment of immune-deficient mice with primitive hematopoietic cells from beta-thalassemia and sickle cell anemia patients: implications for evaluating human gene therapy protocols.
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Academic Article
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B lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi.
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Academic Article
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The role of macrophage colony-stimulating factor in hepatic glucan-induced granuloma formation in the osteopetrosis mutant mouse defective in the production of macrophage colony-stimulating factor.
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Concept
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Disease Models, Animal
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Academic Article
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Overcoming current limitations in humanized mouse research.
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Academic Article
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NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer.
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Academic Article
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Human cancer growth and therapy in immunodeficient mouse models.
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Academic Article
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Generation of improved humanized mouse models for human infectious diseases.
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Academic Article
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Dengue virus infection induces broadly cross-reactive human IgM antibodies that recognize intact virions in humanized BLT-NSG mice.
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Academic Article
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Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors.
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Academic Article
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Humanized Mouse Models for Transplant Immunology.
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Academic Article
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Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary.
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Academic Article
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Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells.
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Academic Article
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A Salmonella nanoparticle mimic overcomes multidrug resistance in tumours.
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Academic Article
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Humanized mouse model of mast cell-mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis.
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Academic Article
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Distinct Differences on Neointima Formation in Immunodeficient and Humanized Mice after Carotid or Femoral Arterial Injury.
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Academic Article
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Humanized Mouse Models of Clinical Disease.
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Academic Article
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Early induction of NRF2 antioxidant pathway by RHBDF2 mediates rapid cutaneous wound healing.
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Academic Article
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Development of Humanized Mice in the Age of Genome Editing.
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Academic Article
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A novel hemolytic complement-sufficient NSG mouse model supports studies of complement-mediated antitumor activity in vivo.
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Academic Article
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Tissue-specific role of RHBDF2 in cutaneous wound healing and hyperproliferative skin disease.
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Academic Article
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Genetic Models of Macrophage Depletion.
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Academic Article
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Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery.
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Academic Article
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Human immune system development and survival of non-obese diabetic (NOD)-scid IL2r?(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells.
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Academic Article
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Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics.
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Academic Article
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Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of a-1 Antitrypsin Deficiency.
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Academic Article
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Co-activation of macrophages and T cells contribute to chronic GVHD in human IL-6 transgenic humanised mouse model.
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Academic Article
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Humanized mouse models of immunological diseases and precision medicine.
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Academic Article
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Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop.
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Academic Article
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Humanized immune system mouse models: progress, challenges and opportunities.
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Academic Article
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Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice Reveals Key Virulence Features.
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Academic Article
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Improved mouse models and advanced genetic and genomic technologies for the study of neutrophils.
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Academic Article
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Innovations, challenges, and minimal information for standardization of humanized mice.
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Academic Article
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Understanding Normal and Malignant Human Hematopoiesis Using Next-Generation Humanized Mice.
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Academic Article
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A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic-related cytokine release syndrome.
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Academic Article
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Dual roles of neutrophils in metastatic colonization are governed by the host NK cell status.
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Academic Article
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Targeting critical kinases and anti-apoptotic molecules overcomes steroid resistance in MLL-rearranged leukaemia.
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Academic Article
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A novel clinically relevant graft-versus-leukemia model in humanized mice.
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Academic Article
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Inactive rhomboid proteins RHBDF1 and RHBDF2 (iRhoms): a decade of research in murine models.
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Academic Article
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Role of MicroRNA in Inflammatory Bowel Disease: Clinical Evidence and the Development of Preclinical Animal Models.
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Academic Article
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Analysis of Salmonella Typhi Pathogenesis in a Humanized Mouse Model.
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Academic Article
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Enhanced development of functional human NK cells in NOD-scid-IL2rgnull mice expressing human IL15.
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Academic Article
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Humanized mouse models for immuno-oncology research.
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Academic Article
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Generation of the NeoThy mouse model for human immune system studies.
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Academic Article
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Simultaneous evaluation of treatment efficacy and toxicity for bispecific T-cell engager therapeutics in a humanized mouse model.
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Academic Article
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Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response.
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Academic Article
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Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice.
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