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Academic Article
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The interleukin-12 beta subunit (p40) maps to mouse chromosome 11.
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Academic Article
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Increased G-CSF responsiveness of bone marrow cells from hematopoietic cell phosphatase deficient viable motheaten mice.
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Academic Article
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Genetic mapping of the IL-12 alpha chain gene (Il12a) on mouse chromosome 3.
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Academic Article
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LacZ and interleukin-3 expression in vivo after retroviral transduction of marrow-derived human osteogenic mesenchymal progenitors.
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Academic Article
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An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice.
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Academic Article
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Lymphadenopathy, elevated serum IgE levels, autoimmunity, and mast cell accumulation in flaky skin mutant mice.
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Academic Article
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Effects of macrophage colony-stimulating factor on macrophages and their related cell populations in the osteopetrosis mouse defective in production of functional macrophage colony-stimulating factor protein.
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Academic Article
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CSF-1 regulation of Il6 gene expression by murine macrophages: a pivotal role for GM-CSF.
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Academic Article
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Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4.
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Academic Article
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Granulocyte/macrophage colony-stimulating factor and interleukin-3 correct osteopetrosis in mice with osteopetrosis mutation.
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Academic Article
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Critical roles for interleukin-4 and interleukin-5 during respiratory syncytial virus infection in the development of airway hyperresponsiveness after airway sensitization.
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Academic Article
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Interleukin (IL)-5 but not immunoglobulin E reconstitutes airway inflammation and airway hyperresponsiveness in IL-4-deficient mice.
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Academic Article
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Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.
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Academic Article
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Age-related alterations in the lymphohematopoietic and B-lineage precursor populations in NZB mice.
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Academic Article
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Establishment and characterization of pro-B cell lines from motheaten mutant mouse defective in SHP-1 protein tyrosine phosphatase.
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Academic Article
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SHP-1 deficiency in B-lineage cells is associated with heightened lyn protein expression and increased lyn kinase activity.
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Academic Article
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Suppressive effects of monocytic cells and transforming growth factor-beta on natural killer cell differentiation in autoimmune viable motheaten mutant mice.
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Academic Article
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IL-5 and eosinophils are essential for the development of airway hyperresponsiveness following acute respiratory syncytial virus infection.
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Academic Article
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The soluble interleukin-6 (IL-6) receptor/IL-6 fusion protein enhances in vitro maintenance and proliferation of human CD34(+)CD38(-/low) cells capable of repopulating severe combined immunodeficiency mice.
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Academic Article
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Induction of the alpha(1)-antichymotrypsin gene in the brain associated with TGF-beta1 deficiency or systemic administration of endotoxin.
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Academic Article
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Purified human hematopoietic stem cells contribute to the generation of cardiomyocytes through cell fusion.
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Academic Article
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Effect of ex vivo cytokine treatment on human cord blood engraftment in NOD-scid mice.
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Academic Article
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Role of gamma interferon and interleukin-4 in host defense against the human filarial parasite Brugia malayi.
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Academic Article
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Intramedullary and extramedullary B lymphopoiesis in osteopetrotic mice.
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Academic Article
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Lipopolysaccharide-induced cytokine and receptor expression and neutrophil infiltration in the liver of osteopetrosis (op/op) mutant mice.
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Academic Article
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Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research.
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Academic Article
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Creation of "humanized" mice to study human immunity.
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Academic Article
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Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment.
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Academic Article
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Fas deficiency delays the resolution of airway hyperresponsiveness after allergen sensitization and challenge.
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Academic Article
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Improved murine model of malaria using Plasmodium falciparum competent strains and non-myelodepleted NOD-scid IL2Rgammanull mice engrafted with human erythrocytes.
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Academic Article
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Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex.
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Academic Article
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Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice.
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Academic Article
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Interleukin-4 receptor-Stat6 signaling in murine infections with a tissue-dwelling nematode parasite.
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Academic Article
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Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.
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Academic Article
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Humanized mouse models to study human diseases.
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Academic Article
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T cell developmental defects in 'viable motheaten' mice deficient in SHP-1 protein-tyrosine phosphatase. Developmental defects are corrected in vitro in the presence of normal hematopoietic-origin stromal cells and in vivo by exogenous IL-7.
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Academic Article
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Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice.
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Academic Article
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Humanized mouse model of ovarian cancer recapitulates patient solid tumor progression, ascites formation, and metastasis.
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Academic Article
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Antibody repertoires in humanized NOD-scid-IL2R?(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse.
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Academic Article
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Humanized mice for immune system investigation: progress, promise and challenges.
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Academic Article
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The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function.
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Academic Article
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T cells are required for host protection against Brugia malayi but need not produce or respond to interleukin-4.
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Academic Article
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Genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice.
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Academic Article
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Regulation of human short-term repopulating cell (STRC) engraftment in NOD/SCID mice by host CD122+ cells.
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Academic Article
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Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice.
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Academic Article
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Novel B-cell maturation factor from spontaneously autoimmune viable motheaten mice.
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Academic Article
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Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice.
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Academic Article
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SHP-1 regulates STAT6 phosphorylation and IL-4-mediated function in a cell type-specific manner.
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Academic Article
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Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells.
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Academic Article
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Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice.
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Academic Article
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TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts.
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Academic Article
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The leukotriene B4 receptor (BLT1) is required for effector CD8+ T cell-mediated, mast cell-dependent airway hyperresponsiveness.
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Academic Article
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A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.
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Academic Article
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Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice.
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Academic Article
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Humanized SCID mouse models for biomedical research.
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Academic Article
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A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function.
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Academic Article
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Expanded CD34+ human umbilical cord blood cells generate multiple lymphohematopoietic lineages in NOD-scid IL2rgamma(null) mice.
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Academic Article
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Human acute leukemia cells injected in NOD/LtSz-scid/IL-2Rgamma null mice generate a faster and more efficient disease compared to other NOD/scid-related strains.
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Academic Article
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Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger.
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Academic Article
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Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat.
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Academic Article
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Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease.
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Academic Article
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Human nasal polyp microenvironments maintained in a viable and functional state as xenografts in NOD-scid IL2rgamma(null) mice.
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Academic Article
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NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection.
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Academic Article
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Identification of therapeutic targets for quiescent, chemotherapy-resistant human leukemia stem cells.
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Academic Article
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Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice.
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Academic Article
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Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection.
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Academic Article
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Hyperglycemia-induced proliferation of adult human beta cells engrafted into spontaneously diabetic immunodeficient NOD-Rag1null IL2r?null Ins2Akita mice.
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Academic Article
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Human peripheral blood CD4 T cell-engrafted non-obese diabetic-scid IL2r?(null) H2-Ab1 (tm1Gru) Tg (human leucocyte antigen D-related 4) mice: a mouse model of human allogeneic graft-versus-host disease.
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Academic Article
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Humanized mice as a preclinical tool for infectious disease and biomedical research.
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Academic Article
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Humanized mice for the study of type 1 and type 2 diabetes.
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Academic Article
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Ex?vivo fucosylation improves human cord blood engraftment in NOD-SCID IL-2R?(null) mice.
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Academic Article
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Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice.
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Academic Article
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Development of mature and functional human myeloid subsets in hematopoietic stem cell-engrafted NOD/SCID/IL2r?KO mice.
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Academic Article
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A serum-derived molecule from autoimmune viable motheaten mice potentiates the action of a B cell maturation factor.
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Academic Article
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Maintenance of CD5+ B cells at an early developmental stage by interleukin-5: evidence from immunoglobulin gene usage in interleukin-5 transgenic mice.
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Academic Article
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Increased B lymphopoiesis in genetically sex steroid-deficient hypogonadal (hpg) mice.
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Concept
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Receptors, Interleukin-1
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Concept
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Receptors, Interleukin-4
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Concept
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Interleukin-2 Receptor alpha Subunit
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Concept
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Interleukin-13
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Concept
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Interleukin-15
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Concept
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Receptors, Interleukin-2
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Concept
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Interleukin-11
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Concept
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Interleukin-1 Receptor-Associated Kinases
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Concept
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Interleukin-5
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Concept
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Interleukin-7
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Concept
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Interleukin-2
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Concept
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Interleukin-1
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Concept
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Receptors, Interleukin-7
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Concept
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Receptors, Interleukin-12
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Concept
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Receptors, Interleukin-6
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Concept
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Interleukin-8
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Concept
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Interleukin-4
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Concept
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Interleukin Receptor Common gamma Subunit
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Concept
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Interleukin-6
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Concept
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Receptors, Interleukin
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Concept
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Interleukin-12
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Concept
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Interleukin-3
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Academic Article
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Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice.
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Academic Article
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Chronic proliferative dermatitis in Sharpin null mice: development of an autoinflammatory disease in the absence of B and T lymphocytes and IL4/IL13 signaling.
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Academic Article
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NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer.
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Academic Article
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Generation of improved humanized mouse models for human infectious diseases.
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Academic Article
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Generation of ? cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice.
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Academic Article
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Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD-scid IL-2rg(null) RIP-DTR mice engrafted with human islets.
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Academic Article
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The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice.
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Academic Article
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Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance.
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Academic Article
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Induction of WT1-specific human CD8+ T cells from human HSCs in HLA class I Tg NOD/SCID/IL2rgKO mice.
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Academic Article
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Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice.
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Academic Article
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Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells.
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Academic Article
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Improved B cell development in humanized NOD-scid IL2R?null mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3.
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Academic Article
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Gene Therapy with an Adeno-Associated Viral Vector Expressing Human Interleukin-2 Alters Immune System Homeostasis in Humanized Mice.
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Academic Article
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Human immune system development and survival of non-obese diabetic (NOD)-scid IL2r?(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells.
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Academic Article
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Co-activation of macrophages and T cells contribute to chronic GVHD in human IL-6 transgenic humanised mouse model.
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Academic Article
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Human NK cell development in hIL-7 and hIL-15 knockin NOD/SCID/IL2rgKO mice.
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Academic Article
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Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice Reveals Key Virulence Features.
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Academic Article
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Enhanced development of functional human NK cells in NOD-scid-IL2rgnull mice expressing human IL15.
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Academic Article
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Human Hematopoietic Stem Cell Engrafted IL-15 Transgenic NSG Mice Support Robust NK Cell Responses and Sustained HIV-1 Infection.
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Academic Article
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Human IL-6 fosters long-term engraftment of patient derived disease-driving myeloma cells in immunodeficient mice.
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Academic Article
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Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice.
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