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Shultz, Leonard
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Academic Article Mapping of the flaky skin (fsn) mutation on distal mouse chromosome 17.
Academic Article The interleukin-12 beta subunit (p40) maps to mouse chromosome 11.
Academic Article CD4+ T cell activation and tolerance induction in B cell knockout mice.
Academic Article Effect of the mouse scid mutation on meiotic recombination.
Academic Article Lack of peripherally induced tolerance to established skin allografts in immunologically reconstituted scid mice.
Academic Article The murine thymic microenvironment: changes with age.
Academic Article Follicular development and ovulation in macrophage colony-stimulating factor-deficient mice homozygous for the osteopetrosis (op) mutation.
Academic Article Development, differentiation, and phenotypic heterogeneity of murine tissue macrophages.
Academic Article Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice.
Academic Article Neural and skin cell-specific expression pattern conferred by steel factor regulatory sequence in transgenic mice.
Academic Article Phenotype and function of human hematopoietic cells engrafting immune-deficient CB17-severe combined immunodeficiency mice and nonobese diabetic-severe combined immunodeficiency mice after transplantation of human cord blood mononuclear cells.
Academic Article Neonatal changes of osteoclasts in osteopetrosis (op/op) mice defective in production of functional macrophage colony-stimulating factor (M-CSF) protein and effects of M-CSF on osteoclast development and differentiation.
Academic Article The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency.
Academic Article Macrophage differentiation and granulomatous inflammation in osteopetrotic mice (op/op) defective in the production of CSF-1.
Academic Article Increased G-CSF responsiveness of bone marrow cells from hematopoietic cell phosphatase deficient viable motheaten mice.
Academic Article Improved engraftment of human cord blood stem cells in NOD/LtSz-scid/scid mice after irradiation or multiple-day injections into unirradiated recipients.
Academic Article Enhanced human CD4+ T cell engraftment in beta2-microglobulin-deficient NOD-scid mice.
Academic Article Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent.
Academic Article CD8+ T lymphocytes are not required for murine resistance to human filarial parasites.
Academic Article Genetic mapping of the IL-12 alpha chain gene (Il12a) on mouse chromosome 3.
Academic Article Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris.
Academic Article Engraftment and development of human CD34(+)-enriched cells from umbilical cord blood in NOD/LtSz-scid/scid mice.
Academic Article Macrophages from motheaten and viable motheaten mutant mice show increased proliferative responses to GM-CSF: detection of potential HCP substrates in GM-CSF signal transduction.
Academic Article Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice.
Academic Article LacZ and interleukin-3 expression in vivo after retroviral transduction of marrow-derived human osteogenic mesenchymal progenitors.
Academic Article Role of tumor necrosis factor-alpha in the spontaneous development of pulmonary fibrosis in viable motheaten mutant mice.
Academic Article An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice.
Academic Article Characteristics of long-term human thyroid peroxidase autoantibody secretion in scid mice transplanted with lymphocytes from patients with autoimmune thyroiditis.
Academic Article Development and progression of psoriasiform dermatitis and systemic lesions in the flaky skin (fsn) mouse mutant.
Academic Article Effects of granulocyte/macrophage colony-stimulating factor on the development and differentiation of CD5-positive macrophages and their potential derivation from a CD5-positive B-cell lineage in mice.
Academic Article Abnormal development and differentiation of macrophages and dendritic cells in viable motheaten mutant mice deficient in haematopoietic cell phosphatase.
Academic Article Mature human hematopoietic cells in donor bone marrow complicate interpretation of stem/progenitor cell assays in xenogeneic hematopoietic chimeras.
Academic Article Diethylcarbamazine (DEC) does not induce nitric oxide (NO) synthesis.
Academic Article Lymphadenopathy, elevated serum IgE levels, autoimmunity, and mast cell accumulation in flaky skin mutant mice.
Academic Article Follicular dendritic cell (FDC) precursors in primary lymphoid tissues.
Academic Article A comparative analysis of the murine thymic microenvironment in normal, autoimmune, and immunodeficiency states.
Academic Article SCID mouse models of human stem cell engraftment.
Academic Article Effects of macrophage colony-stimulating factor on macrophages and their related cell populations in the osteopetrosis mouse defective in production of functional macrophage colony-stimulating factor protein.
Academic Article HIV-1 infectivity of human T cells in a human/murine chimeric fetal thymic organ culture system.
Academic Article Role of nitric oxide in host defense against an extracellular, metazoan parasite, Brugia malayi.
Academic Article Animal models for immunodeficiency diseases.
Academic Article CSF-1 regulation of Il6 gene expression by murine macrophages: a pivotal role for GM-CSF.
Academic Article Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4.
Academic Article Granulocyte/macrophage colony-stimulating factor and interleukin-3 correct osteopetrosis in mice with osteopetrosis mutation.
Academic Article Thymic microenvironment and NZB mice: the abnormal thymic microenvironment of New Zealand mice correlates with immunopathology.
Academic Article Tumorigenicity of green turtle fibropapilloma-derived fibroblast lines in immunodeficient mice.
Academic Article NOD mice have a generalized defect in their response to transplantation tolerance induction.
Academic Article Abnormal thymic expression of epithelial cell adhesion molecule (EP-CAM) in New Zealand Black (NZB) mice.
Academic Article NZB mice exhibit a primary T cell defect in fetal thymic organ culture.
Academic Article Growth of the human filarial parasite Brugia malayi in mice lacking major histocompatibility complex class II antigen expression.
Academic Article Evaluation of monoclonal antibody-mediated anti-acute myeloid leukemia immunotherapy in a SCID/hu model.
Academic Article B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice.
Academic Article Regulation of human cell engraftment and development of EBV-related lymphoproliferative disorders in Hu-PBL-scid mice.
Academic Article The plant lectin FRIL supports prolonged in vitro maintenance of quiescent human cord blood CD34(+)CD38(-/low)/SCID repopulating stem cells.
Academic Article Critical roles for interleukin-4 and interleukin-5 during respiratory syncytial virus infection in the development of airway hyperresponsiveness after airway sensitization.
Academic Article Interleukin (IL)-5 but not immunoglobulin E reconstitutes airway inflammation and airway hyperresponsiveness in IL-4-deficient mice.
Academic Article Mutation of the hematopoietic cell phosphatase (Hcph) gene is associated with resistance to gamma-irradiation-induced apoptosis in Src homology protein tyrosine phosphatase (SHP)-1-deficient "motheaten" mutant mice.
Academic Article Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase.
Academic Article B cells are selectively associated with thymic cortical but not medullary pathology in NZB mice.
Academic Article Increased expression of mXBP-1 (TREB-5) in thymic B cells in New Zealand mice.
Academic Article Macrophage differentiation and expression of macrophage colony-stimulating factor in murine milky spots and omentum after macrophage elimination.
Academic Article Thymic involution in viable motheaten (me(v)) mice is associated with a loss of intrathymic precursor activity.
Academic Article Variables to predict engraftment of umbilical cord blood into immunodeficient mice: usefulness of the non-obese diabetic--severe combined immunodeficient assay.
Academic Article Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice.
Academic Article The molecular bases of spontaneous immunological mutations in the mouse and their homologous human diseases.
Academic Article A null mutation in inositol polyphosphate 4-phosphatase type I causes selective neuronal loss in weeble mutant mice.
Academic Article Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand.
Academic Article DNA-binding antibodies from viable motheaten mutant mice: implications for B cell tolerance.
Academic Article Preservation of functioning human thyroid "organoids" in the scid mouse. IV. In vivo selection of an intrathyroidal T cell receptor repertoire.
Academic Article Blockade of CD40-CD154 interferes with human T cell engraftment in scid mice.
Academic Article Differentiation of epidermal Langerhans cells in macrophage colony-stimulating-factor-deficient mice homozygous for the osteopetrosis (op) mutation.
Academic Article Presence of intestinal intraepithelial lymphocytes in mice with severe combined immunodeficiency disease.
Academic Article Aberrant regulation of bone trace elements in motheaten and osteopetrosis mutant mice.
Academic Article Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.
Academic Article Age-related alterations in the lymphohematopoietic and B-lineage precursor populations in NZB mice.
Academic Article Brugian infections in the peritoneal cavities of laboratory mice: kinetics of infection and cellular responses.
Academic Article Bone remodeling and macrophage differentiation in osteopetrosis (op) mutant mice defective in the production of macrophage colony-stimulating factor.
Academic Article Transgene expression of steel factor in the basal layer of epidermis promotes survival, proliferation, differentiation and migration of melanocyte precursors.
Academic Article Host NK cells are required for the growth of the human filarial parasite Brugia malayi in mice.
Academic Article Prolonged survival of rat islet and skin xenografts in mice treated with donor splenocytes and anti-CD154 monoclonal antibody.
Academic Article The pathophysiological significance of nondesmoglein targets of pemphigus autoimmunity. Development of antibodies against keratinocyte cholinergic receptors in patients with pemphigus vulgaris and pemphigus foliaceus.
Academic Article Establishment and characterization of pro-B cell lines from motheaten mutant mouse defective in SHP-1 protein tyrosine phosphatase.
Academic Article SHP-1 deficiency in B-lineage cells is associated with heightened lyn protein expression and increased lyn kinase activity.
Academic Article Suppressive effects of monocytic cells and transforming growth factor-beta on natural killer cell differentiation in autoimmune viable motheaten mutant mice.
Academic Article Isolation and characterization of a monoclonal anti-quadruplex DNA antibody from autoimmune "viable motheaten" mice.
Academic Article Mutations at the mouse ichthyosis locus are within the lamin B receptor gene: a single gene model for human Pelger-Hu?t anomaly.
Academic Article Continuous infusion of endostatin inhibits differentiation, mobilization, and clonogenic potential of endothelial cell progenitors.
Academic Article Curly bare (cub), a new mouse mutation on chromosome 11 causing skin and hair abnormalities, and a modifier gene (mcub) on chromosome 5.
Academic Article IL-5 and eosinophils are essential for the development of airway hyperresponsiveness following acute respiratory syncytial virus infection.
Academic Article Genetic separation of the transplantation tolerance and autoimmune phenotypes in NOD mice.
Academic Article T cell receptor expression is not required for the localization and differentiation of intraepithelial lymphocytes.
Academic Article Bombesin/gastrin-releasing peptide receptor: a potential target for antibody-mediated therapy of small cell lung cancer.
Academic Article Islet cell autoimmunity and transplantation tolerance: two distinct mechanisms?
Academic Article Roles of a macrophage receptor with collagenous structure (MARCO) in host defense and heterogeneity of splenic marginal zone macrophages.
Academic Article Appearance of human plasma cells following differentiation of human B cells in NOD/SCID mouse spleen.
Academic Article Lipopolysaccharide-induced osteoclastogenesis in Src homology 2-domain phosphatase-1-deficient viable motheaten mice.
Academic Article A new murine model of humoral immuno-deficiency specifically affects class switching to T-independent antigens.
Academic Article Immunity in experimental murine filariasis: roles of T and B cells revisited.
Academic Article Islet allograft survival induced by costimulation blockade in NOD mice is controlled by allelic variants of Idd3.
Academic Article Deficiency of SHP-1 protein-tyrosine phosphatase activity results in heightened osteoclast function and decreased bone density.
Academic Article The soluble interleukin-6 (IL-6) receptor/IL-6 fusion protein enhances in vitro maintenance and proliferation of human CD34(+)CD38(-/low) cells capable of repopulating severe combined immunodeficiency mice.
Academic Article Regulation of skin and islet allograft survival in mice treated with costimulation blockade is mediated by different CD4+ cell subsets and different mechanisms.
Academic Article Immunological mutants of the mouse.
Academic Article Evaluation of donor-specific transfusion sources: unique failure of bone marrow cells to induce prolonged skin allograft survival with anti-CD154 monoclonal antibody.
Academic Article T cells facilitate Brugia malayi development in TCRalpha(null) mice.
Academic Article Induction of the alpha(1)-antichymotrypsin gene in the brain associated with TGF-beta1 deficiency or systemic administration of endotoxin.
Academic Article Apoptosis and the thymic microenvironment in murine lupus.
Academic Article Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes.
Academic Article An assay for human hematopoietic stem cells based on transplantation into nonobese diabetic recombination activating gene-null perforin-null mice.
Academic Article Phorbol ester responsiveness of murine Ly-1-lineage B cells from normal and viable motheaten mutant mice.
Academic Article The Tetratricopeptide repeat domain 7 gene is mutated in flaky skin mice: a model for psoriasis, autoimmunity, and anemia.
Academic Article Human cord blood--derived cells generate insulin-producing cells in vivo.
Academic Article NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells.
Academic Article B1 B lymphocytes play a critical role in host protection against lymphatic filarial parasites.
Academic Article TGF-beta1 inhibits T-bet induction by IFN-gamma in murine CD4+ T cells through the protein tyrosine phosphatase Src homology region 2 domain-containing phosphatase-1.
Academic Article Humanized mice: are we there yet?
Academic Article Expression of terminal differentiation proteins defines stages of mouse mammary gland development.
Academic Article Purified human hematopoietic stem cells contribute to the generation of cardiomyocytes through cell fusion.
Academic Article Isolation of permanent clonal bone marrow stromal cell lines derived from "viable moth-eaten" and "severe combined immunodeficiency" mutant mice.
Academic Article Targeting gastrin-releasing peptide receptors on small cell lung cancer cells with a bispecific molecule that activates polyclonal T lymphocytes.
Academic Article Effect of ex vivo cytokine treatment on human cord blood engraftment in NOD-scid mice.
Academic Article Role of gamma interferon and interleukin-4 in host defense against the human filarial parasite Brugia malayi.
Academic Article beta2 microglobulin-deficient (B2m(null)) NOD/SCID mice are excellent recipients for studying human stem cell function.
Academic Article Intramedullary and extramedullary B lymphopoiesis in osteopetrotic mice.
Academic Article Lanceolate hair-J (lahJ): a mouse model for human hair disorders.
Academic Article Transplantation analysis of B cell destruction in (NOD x CBA)F1 mouse bone marrow chimeras.
Academic Article Inherited mouse mutations as models of human adnexal, cornification, and papulosquamous dermatoses.
Academic Article Effects of macrophage-colony-stimulating factor deficiency on the maturation of microglia and brain macrophages and on their expression of scavenger receptor.
Academic Article Defective macrophage recruitment and clearance of apoptotic cells in the uterus of osteopetrotic mutant mice lacking macrophage colony-stimulating factor (M-CSF).
Academic Article Antibodies against keratinocyte antigens other than desmogleins 1 and 3 can induce pemphigus vulgaris-like lesions.
Academic Article Previously undetected human hematopoietic cell populations with short-term repopulating activity selectively engraft NOD/SCID-beta2 microglobulin-null mice.
Academic Article Lipopolysaccharide-induced cytokine and receptor expression and neutrophil infiltration in the liver of osteopetrosis (op/op) mutant mice.
Academic Article Classification, clinical manifestations, and immunopathological mechanisms of the epithelial variant of paraneoplastic autoimmune multiorgan syndrome: a reappraisal of paraneoplastic pemphigus.
Academic Article Rat xenograft survival in mice treated with donor-specific transfusion and anti-CD154 antibody is enhanced by elimination of host CD4+ cells.
Academic Article Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research.
Academic Article The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene.
Academic Article Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis.
Academic Article Different mechanisms control peripheral and central tolerance in hematopoietic chimeric mice.
Academic Article The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways.
Academic Article Type 1 IFN mediates cross-talk between innate and adaptive immunity that abrogates transplantation tolerance.
Academic Article Effect of aging on epidermal dendritic cell populations in C57BL/6J mice.
Academic Article Macrophage colony-stimulating factor is indispensable for repopulation and differentiation of Kupffer cells but not for splenic red pulp macrophages in osteopetrotic (op/op) mice after macrophage depletion.
Academic Article The differentiative and regenerative properties of human hematopoietic stem/progenitor cells in NOD-SCID/IL2rgamma(null) mice.
Academic Article Creation of "humanized" mice to study human immunity.
Academic Article Mouse neutrophils lacking lamin B-receptor expression exhibit aberrant development and lack critical functional responses.
Academic Article In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties.
Academic Article Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment.
Academic Article The mouse mutant "motheaten". I. Development of lymphocyte populations.
Academic Article Conditioned media from mouse osteosarcoma cells promote MC3T3-E1 cell proliferation using JAKs and PI3-K/Akt signal crosstalk.
Academic Article The mouse mutant "motheaten." II. Functional studies of the immune system.
Academic Article Idd loci synergize to prolong islet allograft survival induced by costimulation blockade in NOD mice.
Academic Article Cancer stem cells are enriched in the side population cells in a mouse model of glioma.
Academic Article Relatively normal human lymphopoiesis but rapid turnover of newly formed B cells in transplanted nonobese diabetic/SCID mice.
Academic Article Fas deficiency delays the resolution of airway hyperresponsiveness after allergen sensitization and challenge.
Academic Article Lymphohemopoiesis in culture is prevented by interaction with adherent bone marrow cells from mutant viable motheaten mice.
Academic Article Improved murine model of malaria using Plasmodium falciparum competent strains and non-myelodepleted NOD-scid IL2Rgammanull mice engrafted with human erythrocytes.
Academic Article Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex.
Academic Article Synthesis of abnormal immunoglobulins by hybridomas from autoimmune "viable motheaten" mutant mice.
Academic Article Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice.
Academic Article In vivo selection of human embryonic stem cell-derived cells expressing methotrexate-resistant dihydrofolate reductase.
Academic Article Dysferlin deficiency and the development of cardiomyopathy in a mouse model of limb-girdle muscular dystrophy 2B.
Academic Article Interleukin-4 receptor-Stat6 signaling in murine infections with a tissue-dwelling nematode parasite.
Academic Article Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.
Academic Article Humanized mouse models to study human diseases.
Academic Article Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent.
Academic Article Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate.
Academic Article Absence of CD5 dramatically reduces progression of pulmonary inflammatory lesions in SHP-1 protein-tyrosine phosphatase-deficient 'viable motheaten' mice.
Academic Article T cell developmental defects in 'viable motheaten' mice deficient in SHP-1 protein-tyrosine phosphatase. Developmental defects are corrected in vitro in the presence of normal hematopoietic-origin stromal cells and in vivo by exogenous IL-7.
Academic Article Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice.
Academic Article Defective in vitro migratory capacity of bone marrow cells from viable motheaten mice in response to normal thymus culture supernatants.
Academic Article Opportunistic bacterial infections in breeding colonies of the NSG mouse strain.
Academic Article Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process.
Academic Article Granuloma formation around filarial larvae triggered by host responses to an excretory/secretory antigen.
Academic Article Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model.
Academic Article Isolation of mouse pancreatic alpha, beta, duct and acinar populations with cell surface markers.
Academic Article Humanized mouse model of ovarian cancer recapitulates patient solid tumor progression, ascites formation, and metastasis.
Academic Article Epidermal growth factor receptors in spontaneous ovarian granulosa cell tumors of SWR-derived mice.
Academic Article Humanized mouse models of HIV-1 latency.
Academic Article Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2r? null mice is enhanced by transgenic expression of membrane-bound human SCF.
Academic Article Pneumocystis carinii pneumonia in scid/scid mice.
Academic Article Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation.
Academic Article Pretargeting vs. direct targeting of human betalox5 islet cells subcutaneously implanted in mice using an anti-human islet cell antibody.
Academic Article Human allograft rejection in humanized mice: a historical perspective.
Academic Article Enhanced humoral and HLA-A2-restricted dengue virus-specific T-cell responses in humanized BLT NSG mice.
Academic Article Characterization of Mott cell hybridomas from autoimmune "viable motheaten" mutant mice.
Academic Article Antibody repertoires in humanized NOD-scid-IL2R?(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse.
Academic Article Dystrophin and dysferlin double mutant mice: a novel model for rhabdomyosarcoma.
Academic Article Humanized mouse model used to monitor MUC gene expression in nasal polyps and to preclinically evaluate the efficacy of montelukast in reducing mucus production.
Academic Article In vitro and in vivo hematopoietic potential of human stem cells residing in muscle tissue.
Academic Article Establishment and characterization of a new osteogenic cell line (MOS-J) from a spontaneous C57BL/6J mouse osteosarcoma.
Academic Article Humanized mice for immune system investigation: progress, promise and challenges.
Academic Article Inflammatory dilated cardiomyopathy in Abcg5-deficient mice.
Academic Article Increased frequency of pre-pro B cells in the bone marrow of New Zealand Black (NZB) mice: implications for a developmental block in B cell differentiation.
Academic Article Defective repair of radiation-induced chromosomal damage in scid/scid mice.
Academic Article Retrotransposon insertion in the T-cell acute lymphocytic leukemia 1 (Tal1) gene is associated with severe renal disease and patchy alopecia in Hairpatches (Hpt) mice.
Academic Article GLI1 regulates a novel neuropilin-2/a6?1 integrin based autocrine pathway that contributes to breast cancer initiation.
Academic Article Primed peritoneal B lymphocytes are sufficient to transfer protection against Brugia pahangi infection in mice.
Academic Article A pyrrolo-pyrimidine derivative targets human primary AML stem cells in vivo.
Academic Article Gene for ovarian granulosa cell tumor susceptibility, Gct, in SWXJ recombinant inbred strains of mice revealed by dehydroepiandrosterone.
Academic Article The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function.
Academic Article Mechanisms of anemia in SHP-1 protein tyrosine phosphatase-deficient "viable motheaten" mice.
Academic Article Changes in ovarian tumor cell number, tumor vasculature, and T cell function monitored in vivo using a novel xenograft model.
Academic Article T cells are required for host protection against Brugia malayi but need not produce or respond to interleukin-4.
Academic Article Mouse models of genetic diseases.
Academic Article Pleiotropic effects of deleterious alleles at the "motheaten" locus.
Academic Article Development of plasmacytoid cells with Russell bodies in autoimmune "viable motheaten" mice.
Academic Article Defective lymphopoiesis in the bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. II. Description of a microenvironmental defect for the generation of terminal deoxynucleotidyltransferase-positive bone marrow cells in vitro.
Academic Article Pleiotropic mutations causing abnormalities in the murine immune system and the skin.
Academic Article Genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice.
Academic Article Regulation of human short-term repopulating cell (STRC) engraftment in NOD/SCID mice by host CD122+ cells.
Academic Article Hematopoiesis and models of immunodeficiency.
Academic Article Evaluation of the mouse mutant "wasted" as an animal model for ataxia telangiectasia. I. Age-dependent and tissue-specific effects.
Academic Article Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice.
Academic Article NOD/LtSz-Rag1nullPfpnull mice: a new model system with increased levels of human peripheral leukocyte and hematopoietic stem-cell engraftment.
Academic Article Hairpatches, a single gene mutation characterized by progressive renal disease and alopecia in the mouse. A potential model for a newly described heritable human disorder.
Academic Article Distinct osteoclast precursors in the bone marrow and extramedullary organs characterized by responsiveness to Toll-like receptor ligands and TNF-alpha.
Academic Article Evaluations of wasted mouse fibroblasts and SV-40 transformed human fibroblasts as models of ataxia telangiectasia in vitro.
Academic Article The effect of immunosuppression on streptozotocin-induced diabetes in C57BL/KsJ mice.
Academic Article Immunodeficiency and reticulum cell sarcoma in mice segregating for HRS/J and SJL/J genes.
Academic Article Novel B-cell maturation factor from spontaneously autoimmune viable motheaten mice.
Academic Article Hematopoietic stem cell function in motheaten mice.
Academic Article "Viable motheaten," a new allele at the motheaten locus. I. Pathology.
Academic Article 'Wasted', a new mutant of the mouse with abnormalities characteristic to ataxia telangiectasia.
Academic Article The contribution of mast cells to the histamine content of the central nervous system: a regional analysis.
Academic Article Transgenic mice expressing either bovine growth hormone (bGH) or human GH releasing hormone (hGRH) have increased splenic progenitor cell colony formation and DNA synthesis in vitro and in vivo.
Academic Article Recapitulation of normal and abnormal BB rat immune system development in scid mouse/rat lymphohemopoietic chimeras.
Academic Article High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to human immunodeficiency virus type 1 infection in NOD/LtSz-scid/scid mice.
Academic Article Graves' disease thyroid tissue transplants in scid mice: persistent selectivity in hTcR Va gene family use.
Academic Article The flaky skin (fsn) mutation in mice: map location and description of the anemia.
Academic Article Emv30null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells.
Academic Article Cellular origin of follicular dendritic cells.
Academic Article Maternal influence on susceptibility of offspring to Brugia malayi infection in a murine model of filariasis.
Academic Article Islet-infiltrating lymphocytes from prediabetic NOD mice rapidly transfer diabetes to NOD-scid/scid mice.
Academic Article Abnormal nuclear morphology of leukocytes in the mouse mutant ichthyosis.
Academic Article Human bone marrow and umbilical cord blood cells generate CD4+ and CD8+ single-positive T cells in murine fetal thymus organ culture.
Academic Article CD4+ T-lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi.
Academic Article Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice.
Academic Article Influence of gonadal steroids on susceptibility to Brugia malayi in scid mice.
Academic Article Engraftment of human lymphocytes and thyroid tissue into scid and rag2-deficient mice: absent progression of lymphocytic infiltration.
Academic Article Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors.
Academic Article Preservation of functioning human thyroid "organoids" in the severe combined immunodeficient mouse. III. Thyrotropin independence of thyroid follicle formation.
Academic Article Anti-CD11b antibody prevents immunopathologic changes in viable moth-eaten bone marrow chimeric mice.
Academic Article Granulosa cell tumorigenesis in genetically hypogonadal-immunodeficient mice grafted with ovaries from tumor-susceptible donors.
Academic Article Preservation of functioning human thyroid organoids in the scid mouse: 1. System characterization.
Academic Article Preservation of functioning human thyroid organoids in the scid mouse: II. Biased use of intrathyroidal T cell receptor V genes.
Academic Article Cellular requirements for functional reconstitution of follicular dendritic cells in SCID mice.
Academic Article Epidermal dendritic cell populations in the flaky skin mutant mouse.
Academic Article Differentiation of dendritic cell populations in macrophage colony-stimulating factor-deficient mice homozygous for the osteopetrosis (op) mutation.
Academic Article Abnormal differentiation of tissue macrophage populations in 'osteopetrosis' (op) mice defective in the production of macrophage colony-stimulating factor.
Academic Article Prolonged survival of neonatal porcine islet xenografts in mice treated with a donor-specific transfusion and anti-CD154 antibody.
Academic Article Immunodeficient mice as hosts for hemoparasitic infections.
Academic Article Rejection of human islets and human HLA-A2.1 transgenic mouse islets by alloreactive human lymphocytes in immunodeficient NOD-scid and NOD-Rag1(null)Prf1(null) mice.
Academic Article Human cord blood- and bone marrow-derived CD34+ cells regenerate gastrointestinal epithelial cells.
Academic Article SHP-1 regulates STAT6 phosphorylation and IL-4-mediated function in a cell type-specific manner.
Academic Article Autoimmune diabetes and resistance to xenograft transplantation tolerance in NOD mice.
Academic Article Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells.
Academic Article Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice.
Academic Article Efficient engraftment of primary adult T-cell leukemia cells in newborn NOD/SCID/beta2-microglobulin(null) mice.
Academic Article The immunodeficient scid mouse as a model for human lymphatic filariasis.
Academic Article Accelerated wound healing of alkali-burned corneas in MRL mice is associated with a reduced inflammatory signature.
Academic Article TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts.
Academic Article The leukotriene B4 receptor (BLT1) is required for effector CD8+ T cell-mediated, mast cell-dependent airway hyperresponsiveness.
Academic Article Deficiency of SHP-1 protein-tyrosine phosphatase in "viable motheaten" mice results in retinal degeneration.
Academic Article The SCID-hu mouse and thyroid autoimmunity: characterization of human thyroid autoantibody secretion.
Academic Article Treatment and transfer of emphysema by a new bone marrow transplantation method from normal mice to Tsk mice and vice versa.
Academic Article Anti-mouse CD154 antibody treatment facilitates generation of mixed xenogeneic rat hematopoietic chimerism, prevents wasting disease and prolongs xenograft survival in mice.
Academic Article In vivo distribution of human adipose-derived mesenchymal stem cells in novel xenotransplantation models.
Academic Article Constant rate of steady-state self-antigen trafficking from skin to regional lymph nodes.
Academic Article Humanized mice in translational biomedical research.
Academic Article Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity.
Academic Article Effect of genetically determined immunodeficiency on epidermal dendritic cell populations in C57BL/6J mice.
Academic Article Acute but not chronic macrophage recruitment in filarial infections in mice is dependent on C-C chemokine ligand 2.
Academic Article Determinants of memory in experimental filarial infections in mice.
Academic Article Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.
Academic Article A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.
Academic Article CD34+CD38+CD19+ as well as CD34+CD38-CD19+ cells are leukemia-initiating cells with self-renewal capacity in human B-precursor ALL.
Academic Article Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice.
Academic Article Humanized SCID mouse models for biomedical research.
Academic Article A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function.
Academic Article Expanded CD34+ human umbilical cord blood cells generate multiple lymphohematopoietic lineages in NOD-scid IL2rgamma(null) mice.
Academic Article Human acute leukemia cells injected in NOD/LtSz-scid/IL-2Rgamma null mice generate a faster and more efficient disease compared to other NOD/scid-related strains.
Academic Article T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice.
Academic Article Human BLyS facilitates engraftment of human PBL derived B cells in immunodeficient mice.
Academic Article Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger.
Academic Article Humanized mice for the study of type 1 diabetes and beta cell function.
Academic Article Effect of DNA-damaging agents on isolated spleen cells and lung fibroblasts from the mouse mutant "wasted," a putative animal model for ataxia-telangiectasia.
Academic Article The mouse mutant "wasted": an animal model for ataxia-telangiectasia.
Academic Article Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice.
Academic Article TLR agonists prevent the establishment of allogeneic hematopoietic chimerism in mice treated with costimulation blockade.
Academic Article Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat.
Academic Article Bioluminescent imaging demonstrates that transplanted human embryonic stem cell-derived CD34(+) cells preferentially develop into endothelial cells.
Academic Article Identification of Pneumocystis carinii in immunodeficient mice.
Academic Article The mouse mutation "thrombocytopenia and cardiomyopathy" (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia.
Academic Article Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease.
Academic Article Targeted delivery of small interfering RNA to human dendritic cells to suppress dengue virus infection and associated proinflammatory cytokine production.
Academic Article Human nasal polyp microenvironments maintained in a viable and functional state as xenografts in NOD-scid IL2rgamma(null) mice.
Academic Article NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection.
Academic Article Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.
Academic Article Identification of therapeutic targets for quiescent, chemotherapy-resistant human leukemia stem cells.
Academic Article Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice.
Academic Article Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection.
Academic Article High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias.
Academic Article Adenosine deaminase activity in recipients of bone marrow from immunodeficient mice homozygous for the wasted mutation.
Academic Article Outbreaks of Pneumocystis carinii pneumonia in colonies of immunodeficient mice.
Academic Article HLA-A2-matched peripheral blood mononuclear cells from type 1 diabetic patients, but not nondiabetic donors, transfer insulitis to NOD-scid/?c(null)/HLA-A2 transgenic mice concurrent with the expansion of islet-specific CD8+ T cells.
Academic Article A deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulation.
Academic Article Hyperglycemia-induced proliferation of adult human beta cells engrafted into spontaneously diabetic immunodeficient NOD-Rag1null IL2r?null Ins2Akita mice.
Academic Article Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids.
Academic Article Human peripheral blood CD4 T cell-engrafted non-obese diabetic-scid IL2r?(null) H2-Ab1 (tm1Gru) Tg (human leucocyte antigen D-related 4) mice: a mouse model of human allogeneic graft-versus-host disease.
Academic Article Hematologic abnormalities of the immunodeficient mouse mutant, viable motheaten (mev).
Academic Article Humanized mice as a preclinical tool for infectious disease and biomedical research.
Academic Article Humanized mice for the study of type 1 and type 2 diabetes.
Academic Article Ex?vivo fucosylation improves human cord blood engraftment in NOD-SCID IL-2R?(null) mice.
Academic Article Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice.
Academic Article Development of mature and functional human myeloid subsets in hematopoietic stem cell-engrafted NOD/SCID/IL2r?KO mice.
Academic Article The mouse mutation severe combined immune deficiency (scid) is on chromosome 16.
Academic Article Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo.
Academic Article Islet-specific CTL cloned from a type 1 diabetes patient cause beta-cell destruction after engraftment into HLA-A2 transgenic NOD/scid/IL2RG null mice.
Academic Article Microenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt-?-catenin signaling.
Academic Article Loss of function of the mouse Sharpin gene results in Peyer's patch regression.
Academic Article Suppression of SHP-1 promotes corticospinal tract sprouting and functional recovery after brain injury.
Academic Article Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming.
Academic Article Humanized mice for the study of infectious diseases.
Academic Article A new in vivo screening paradigm to accelerate antimalarial drug discovery.
Academic Article Attenuation of exogenous murine mammary tumor virus virulence in the C3H/HeJ mouse substrain bearing the Lps mutation.
Academic Article Non-germ-line elements (NGE) are present in the T cell receptor beta-chain genes isolated from the mutant mouse, motheaten (me/me).
Academic Article NOD marrow stem cells adoptively transfer diabetes to resistant (NOD x NON)F1 mice.
Academic Article The immunological mouse mutants nude (nu) and rhino (hrrh) generate cytotoxic effector cells following adoptive immunotherapy but fail to reject a transplanted tumor.
Academic Article Adenosine deaminase activity in recipients of bone marrow from immunodeficient mice homozygous for the wasted mutation.
Academic Article Genetically determined murine models of immunodeficiency.
Academic Article Production of immunoglobulin isotypes by Ly-1+ B cells in viable motheaten and normal mice.
Academic Article Defective lymphopoiesis in the bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. III. Normal mouse bone marrow cells enable mev/mev prothymocytes to generate thymocytes after intravenous transfer.
Academic Article Effect of immunodeficiency on diabetogenesis in genetically diabetic (db/db) mice.
Academic Article Motheaten, an immunodeficient mutant of the mouse. II. Depressed immune competence and elevated serum immunoglobulins.
Academic Article A serum-derived molecule from autoimmune viable motheaten mice potentiates the action of a B cell maturation factor.
Academic Article Gamma-interferon is one of several direct B cell-maturing lymphokines.
Academic Article Mutations in mice that influence natural killer (NK) cell activity.
Academic Article In the absence of a CD40 signal, B cells are tolerogenic.
Academic Article Thymic epithelial cell abnormalities in (NZB x H-2u)F1 mice.
Academic Article Maintenance of CD5+ B cells at an early developmental stage by interleukin-5: evidence from immunoglobulin gene usage in interleukin-5 transgenic mice.
Academic Article Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with C.B-17-scid/scid mice.
Academic Article Engraftment of immune-deficient mice with primitive hematopoietic cells from beta-thalassemia and sickle cell anemia patients: implications for evaluating human gene therapy protocols.
Academic Article Maintenance of the human malarial parasite, Plasmodium falciparum, in scid mice and transmission of gametocytes to mosquitoes.
Academic Article B lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi.
Academic Article Programmed differentiation of murine thymocytes during fetal thymus organ culture.
Academic Article Antiviral activity of NK 1.1+ natural killer cells in C57BL/6 scid mice infected with murine cytomegalovirus.
Academic Article Motheaten, an immunodeficient mutant of the mouse. I. Genetics and pathology.
Academic Article Increased B lymphopoiesis in genetically sex steroid-deficient hypogonadal (hpg) mice.
Academic Article Localization of prothymocytes from wild-type and viable motheaten mice following intravenous injection into irradiated adoptive recipients.
Academic Article Ultrastructure of macrophages and dendritic cells in osteopetrosis (op) mutant mice lacking macrophage colony-stimulating factor (M-CSF/CSF-1) activity.
Academic Article Effects of macrophage colony-stimulating factor (M-CSF) on the development, differentiation, and maturation of marginal metallophilic macrophages and marginal zone macrophages in the spleen of osteopetrosis (op) mutant mice lacking functional M-CSF activity.
Academic Article The role of macrophage colony-stimulating factor in hepatic glucan-induced granuloma formation in the osteopetrosis mutant mouse defective in the production of macrophage colony-stimulating factor.
Academic Article Acute, lethal, natural killer cell-resistant myeloproliferative disease induced by polyomavirus in severe combined immunodeficient mice.
Academic Article Multiple low-dose streptozocin-induced diabetes in NOD-scid/scid mice in the absence of functional lymphocytes.
Academic Article Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene.
Academic Article Induction of functional follicular dendritic cell development in severe combined immunodeficiency mice. Influence of B and T cells.
Concept Mice, Inbred CBA
Concept Mice, Inbred BALB C
Concept Mice, Obese
Concept Mice, Inbred MRL lpr
Concept Mice, Hairless
Concept Mice, Knockout
Concept Mice, Inbred C3H
Concept Mice, Inbred SENCAR
Concept Mice
Concept Mice, Inbred ICR
Concept Mice, Inbred C57BL
Concept Mice, Transgenic
Concept Mammary Tumor Virus, Mouse
Concept Mice, Inbred NOD
Concept Mice, Inbred A
Concept Mice, Inbred AKR
Concept Mice, Nude
Concept Mice, SCID
Concept Mice, Congenic
Concept Mice, Inbred Strains
Concept Mice, Inbred NZB
Concept Mice, Neurologic Mutants
Concept Mice, Inbred DBA
Concept Mice, Mutant Strains
Academic Article Overcoming current limitations in humanized mouse research.
Academic Article Comparison between two labeled agents in mice using a coinjection-ratio approach in contrast to a conventional group approach.
Academic Article Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice.
Academic Article Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice.
Academic Article Improved function and proliferation of adult human beta cells engrafted in diabetic immunodeficient NOD-scid IL2r?(null) mice treated with alogliptin.
Academic Article c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.
Academic Article Chronic proliferative dermatitis in Sharpin null mice: development of an autoinflammatory disease in the absence of B and T lymphocytes and IL4/IL13 signaling.
Academic Article An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
Academic Article NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer.
Academic Article Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.
Academic Article Subcapsular transplantation of tissue in the kidney.
Academic Article Human cancer growth and therapy in immunodeficient mouse models.
Academic Article Immunodeficient mouse model for human hematopoietic stem cell engraftment and immune system development.
Academic Article Viral infection of engrafted human islets leads to diabetes.
Academic Article Generation of improved humanized mouse models for human infectious diseases.
Academic Article Inhibition of bromodomain proteins for the treatment of human diffuse large B-cell lymphoma.
Academic Article Dengue virus infection induces broadly cross-reactive human IgM antibodies that recognize intact virions in humanized BLT-NSG mice.
Academic Article Generation of ? cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice.
Academic Article Identification of CD34+ and CD34- leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemia.
Academic Article MEK guards proteome stability and inhibits tumor-suppressive amyloidogenesis via HSF1.
Academic Article Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.
Academic Article Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD-scid IL-2rg(null) RIP-DTR mice engrafted with human islets.
Academic Article The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice.
Academic Article Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection.
Academic Article Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors.
Academic Article P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer.
Academic Article Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic ?-cell function via glycogen synthase kinase-3?.
Academic Article Humanized Mouse Models for Transplant Immunology.
Academic Article Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance.
Academic Article Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary.
Academic Article Induction of WT1-specific human CD8+ T cells from human HSCs in HLA class I Tg NOD/SCID/IL2rgKO mice.
Academic Article Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice.
Academic Article Stress-impaired transcription factor expression and insulin secretion in transplanted human islets.
Academic Article Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells.
Academic Article Genetically modified human CD4(+) T cells can be evaluated in?vivo without lethal graft-versus-host disease.
Academic Article Cell-Extrinsic MHC Class I Molecule Engagement Augments Human NK Cell Education Programmed by Cell-Intrinsic MHC Class I.
Academic Article Combined B, T and NK Cell Deficiency Accelerates Atherosclerosis in BALB/c Mice.
Academic Article Humanized mouse model of mast cell-mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis.
Academic Article Distinct Differences on Neointima Formation in Immunodeficient and Humanized Mice after Carotid or Femoral Arterial Injury.
Academic Article Humanized Mouse Models of Clinical Disease.
Academic Article Improved B cell development in humanized NOD-scid IL2R?null mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3.
Academic Article Analysis of parameters that affect human hematopoietic cell outputs in mutant c-kit-immunodeficient mice.
Academic Article Engraftment of Human Primary Acute Myeloid Leukemia Defined by Integrated Genetic Profiling in NOD/SCID/IL2r?null Mice for Preclinical Ceramide-Based Therapeutic Evaluation.
Academic Article Early induction of NRF2 antioxidant pathway by RHBDF2 mediates rapid cutaneous wound healing.
Academic Article Development of Humanized Mice in the Age of Genome Editing.
Academic Article A novel hemolytic complement-sufficient NSG mouse model supports studies of complement-mediated antitumor activity in vivo.
Academic Article mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell-derived hematopoietic progenitors.
Academic Article Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosis.
Academic Article Age-dependent human ? cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.
Academic Article Overcoming mutational complexity in acute myeloid leukemia by inhibition of critical pathways.
Academic Article a Cell Function and Gene Expression Are Compromised in Type 1 Diabetes.
Academic Article Gene Therapy with an Adeno-Associated Viral Vector Expressing Human Interleukin-2 Alters Immune System Homeostasis in Humanized Mice.
Academic Article Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression.
Academic Article Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy.
Academic Article Tissue-specific role of RHBDF2 in cutaneous wound healing and hyperproliferative skin disease.
Academic Article Genetic Models of Macrophage Depletion.
Academic Article Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic ? Cells for In?Vitro and In?Vivo Analysis.
Academic Article Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery.
Academic Article A novel patient-derived tumorgraft model with TRAF1-ALK anaplastic large-cell lymphoma translocation.
Academic Article Human immune system development and survival of non-obese diabetic (NOD)-scid IL2r?(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells.
Academic Article Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics.
Academic Article Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of a-1 Antitrypsin Deficiency.
Academic Article Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1.
Academic Article Co-activation of macrophages and T cells contribute to chronic GVHD in human IL-6 transgenic humanised mouse model.
Academic Article Humanized mouse models of immunological diseases and precision medicine.
Academic Article Human NK cell development in hIL-7 and hIL-15 knockin NOD/SCID/IL2rgKO mice.
Academic Article Humanized immune system mouse models: progress, challenges and opportunities.
Academic Article AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice.
Academic Article Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice Reveals Key Virulence Features.
Academic Article Identification of a tumor-specific allo-HLA-restricted ?dTCR.
Academic Article Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells.
Academic Article Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain.
Academic Article Recovery of viable endocrine-specific cells and transcriptomes from human pancreatic islet-engrafted mice.
Academic Article Tacrolimus- and sirolimus-induced human ? cell dysfunction is reversible and preventable.
Academic Article TEG011 persistence averts extramedullary tumor growth without exerting off-target toxicity against healthy tissues in a humanized HLA-A*24:02 transgenic mice.
Academic Article Improved mouse models and advanced genetic and genomic technologies for the study of neutrophils.
Academic Article Dapagliflozin Does Not Directly Affect Human a or ? Cells.
Academic Article Innovations, challenges, and minimal information for standardization of humanized mice.
Academic Article Genes adapt to outsmart gene-targeting strategies in mutant mouse strains by skipping exons to reinitiate transcription and translation.
Academic Article Understanding Normal and Malignant Human Hematopoiesis Using Next-Generation Humanized Mice.
Academic Article A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic-related cytokine release syndrome.
Academic Article Dual roles of neutrophils in metastatic colonization are governed by the host NK cell status.
Academic Article Lung mesenchymal cells elicit lipid storage in neutrophils that fuel breast cancer lung metastasis.
Academic Article Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy.
Academic Article Targeting critical kinases and anti-apoptotic molecules overcomes steroid resistance in MLL-rearranged leukaemia.
Academic Article A novel clinically relevant graft-versus-leukemia model in humanized mice.
Academic Article Inactive rhomboid proteins RHBDF1 and RHBDF2 (iRhoms): a decade of research in murine models.
Academic Article Role of MicroRNA in Inflammatory Bowel Disease: Clinical Evidence and the Development of Preclinical Animal Models.
Academic Article Novel phosphatidylserine-binding molecule enhances antitumor T-cell responses by targeting immunosuppressive exosomes in human tumor microenvironments.
Academic Article Circulating CD34+?cells of primary myelofibrosis patients contribute to myeloid-dominant hematopoiesis and bone marrow fibrosis in immunodeficient mice.
Academic Article Analysis of Salmonella Typhi Pathogenesis in a Humanized Mouse Model.
Academic Article Enhanced development of functional human NK cells in NOD-scid-IL2rgnull mice expressing human IL15.
Academic Article Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells.
Academic Article Humanized mouse models for immuno-oncology research.
Academic Article Immunosuppressive reprogramming of neutrophils by lung mesenchymal cells promotes breast cancer metastasis.
Academic Article NOD-scid IL2r?null mice lacking TLR4 support human immune system development and the study of human-specific innate immunity.
Academic Article Human Hematopoietic Stem Cell Engrafted IL-15 Transgenic NSG Mice Support Robust NK Cell Responses and Sustained HIV-1 Infection.
Academic Article Generation of the NeoThy mouse model for human immune system studies.
Academic Article Simultaneous evaluation of treatment efficacy and toxicity for bispecific T-cell engager therapeutics in a humanized mouse model.
Academic Article Characterization and isolation of melanocyte progenitors from mouse embryos.
Academic Article Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response.
Academic Article Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma.
Academic Article Expression of endogenous murine leukaemia viruses in AKR/J streaker mice.
Academic Article Human IL-6 fosters long-term engraftment of patient derived disease-driving myeloma cells in immunodeficient mice.
Academic Article Nuclear factor kappa B-dependent persistence of Salmonella Typhi and Paratyphi in human macrophages.
Academic Article Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice.
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