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Shultz, Leonard

One or more keywords matched the following items that are connected to Shultz, Leonard

Item Type	Name
Academic Article	Neonatal changes of osteoclasts in osteopetrosis (op/op) mice defective in production of functional macrophage colony-stimulating factor (M-CSF) protein and effects of M-CSF on osteoclast development and differentiation.
Academic Article	Macrophage differentiation and granulomatous inflammation in osteopetrotic mice (op/op) defective in the production of CSF-1.
Academic Article	Increased G-CSF responsiveness of bone marrow cells from hematopoietic cell phosphatase deficient viable motheaten mice.
Academic Article	CD8+ T lymphocytes are not required for murine resistance to human filarial parasites.
Academic Article	Macrophages from motheaten and viable motheaten mutant mice show increased proliferative responses to GM-CSF: detection of potential HCP substrates in GM-CSF signal transduction.
Academic Article	Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice.
Academic Article	Role of tumor necrosis factor-alpha in the spontaneous development of pulmonary fibrosis in viable motheaten mutant mice.
Academic Article	An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice.
Academic Article	Development and progression of psoriasiform dermatitis and systemic lesions in the flaky skin (fsn) mouse mutant.
Academic Article	Abnormal development and differentiation of macrophages and dendritic cells in viable motheaten mutant mice deficient in haematopoietic cell phosphatase.
Academic Article	Lymphadenopathy, elevated serum IgE levels, autoimmunity, and mast cell accumulation in flaky skin mutant mice.
Academic Article	Effects of macrophage colony-stimulating factor on macrophages and their related cell populations in the osteopetrosis mouse defective in production of functional macrophage colony-stimulating factor protein.
Academic Article	Granulocyte/macrophage colony-stimulating factor and interleukin-3 correct osteopetrosis in mice with osteopetrosis mutation.
Academic Article	B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice.
Academic Article	Mutation of the hematopoietic cell phosphatase (Hcph) gene is associated with resistance to gamma-irradiation-induced apoptosis in Src homology protein tyrosine phosphatase (SHP)-1-deficient "motheaten" mutant mice.
Academic Article	Thymic involution in viable motheaten (me(v)) mice is associated with a loss of intrathymic precursor activity.
Academic Article	Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice.
Academic Article	The molecular bases of spontaneous immunological mutations in the mouse and their homologous human diseases.
Academic Article	DNA-binding antibodies from viable motheaten mutant mice: implications for B cell tolerance.
Academic Article	Differentiation of epidermal Langerhans cells in macrophage colony-stimulating-factor-deficient mice homozygous for the osteopetrosis (op) mutation.
Academic Article	Presence of intestinal intraepithelial lymphocytes in mice with severe combined immunodeficiency disease.
Academic Article	Aberrant regulation of bone trace elements in motheaten and osteopetrosis mutant mice.
Academic Article	Bone remodeling and macrophage differentiation in osteopetrosis (op) mutant mice defective in the production of macrophage colony-stimulating factor.
Academic Article	Suppressive effects of monocytic cells and transforming growth factor-beta on natural killer cell differentiation in autoimmune viable motheaten mutant mice.
Academic Article	Isolation and characterization of a monoclonal anti-quadruplex DNA antibody from autoimmune "viable motheaten" mice.
Academic Article	Lipopolysaccharide-induced osteoclastogenesis in Src homology 2-domain phosphatase-1-deficient viable motheaten mice.
Academic Article	Deficiency of SHP-1 protein-tyrosine phosphatase activity results in heightened osteoclast function and decreased bone density.
Academic Article	Immunological mutants of the mouse.
Academic Article	Induction of the alpha(1)-antichymotrypsin gene in the brain associated with TGF-beta1 deficiency or systemic administration of endotoxin.
Academic Article	Phorbol ester responsiveness of murine Ly-1-lineage B cells from normal and viable motheaten mutant mice.
Academic Article	Isolation of permanent clonal bone marrow stromal cell lines derived from "viable moth-eaten" and "severe combined immunodeficiency" mutant mice.
Academic Article	Lanceolate hair-J (lahJ): a mouse model for human hair disorders.
Academic Article	Inherited mouse mutations as models of human adnexal, cornification, and papulosquamous dermatoses.
Academic Article	The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene.
Academic Article	Macrophage colony-stimulating factor is indispensable for repopulation and differentiation of Kupffer cells but not for splenic red pulp macrophages in osteopetrotic (op/op) mice after macrophage depletion.
Academic Article	Fas deficiency delays the resolution of airway hyperresponsiveness after allergen sensitization and challenge.
Academic Article	Lymphohemopoiesis in culture is prevented by interaction with adherent bone marrow cells from mutant viable motheaten mice.
Academic Article	Synthesis of abnormal immunoglobulins by hybridomas from autoimmune "viable motheaten" mutant mice.
Academic Article	Interleukin-4 receptor-Stat6 signaling in murine infections with a tissue-dwelling nematode parasite.
Academic Article	Absence of CD5 dramatically reduces progression of pulmonary inflammatory lesions in SHP-1 protein-tyrosine phosphatase-deficient 'viable motheaten' mice.
Academic Article	T cell developmental defects in 'viable motheaten' mice deficient in SHP-1 protein-tyrosine phosphatase. Developmental defects are corrected in vitro in the presence of normal hematopoietic-origin stromal cells and in vivo by exogenous IL-7.
Academic Article	Defective in vitro migratory capacity of bone marrow cells from viable motheaten mice in response to normal thymus culture supernatants.
Academic Article	Pneumocystis carinii pneumonia in scid/scid mice.
Academic Article	Human allograft rejection in humanized mice: a historical perspective.
Academic Article	Characterization of Mott cell hybridomas from autoimmune "viable motheaten" mutant mice.
Academic Article	The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function.
Academic Article	Mechanisms of anemia in SHP-1 protein tyrosine phosphatase-deficient "viable motheaten" mice.
Academic Article	Development of plasmacytoid cells with Russell bodies in autoimmune "viable motheaten" mice.
Academic Article	Defective lymphopoiesis in the bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. II. Description of a microenvironmental defect for the generation of terminal deoxynucleotidyltransferase-positive bone marrow cells in vitro.
Academic Article	Pleiotropic mutations causing abnormalities in the murine immune system and the skin.
Academic Article	Evaluation of the mouse mutant "wasted" as an animal model for ataxia telangiectasia. I. Age-dependent and tissue-specific effects.
Academic Article	Hairpatches, a single gene mutation characterized by progressive renal disease and alopecia in the mouse. A potential model for a newly described heritable human disorder.
Academic Article	Evaluations of wasted mouse fibroblasts and SV-40 transformed human fibroblasts as models of ataxia telangiectasia in vitro.
Academic Article	Novel B-cell maturation factor from spontaneously autoimmune viable motheaten mice.
Academic Article	Hematopoietic stem cell function in motheaten mice.
Academic Article	'Wasted', a new mutant of the mouse with abnormalities characteristic to ataxia telangiectasia.
Academic Article	The contribution of mast cells to the histamine content of the central nervous system: a regional analysis.
Academic Article	Recapitulation of normal and abnormal BB rat immune system development in scid mouse/rat lymphohemopoietic chimeras.
Academic Article	The flaky skin (fsn) mutation in mice: map location and description of the anemia.
Academic Article	Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice.
Academic Article	Anti-CD11b antibody prevents immunopathologic changes in viable moth-eaten bone marrow chimeric mice.
Academic Article	Epidermal dendritic cell populations in the flaky skin mutant mouse.
Academic Article	Differentiation of dendritic cell populations in macrophage colony-stimulating factor-deficient mice homozygous for the osteopetrosis (op) mutation.
Academic Article	Abnormal differentiation of tissue macrophage populations in 'osteopetrosis' (op) mice defective in the production of macrophage colony-stimulating factor.
Academic Article	The immunodeficient scid mouse as a model for human lymphatic filariasis.
Academic Article	Deficiency of SHP-1 protein-tyrosine phosphatase in "viable motheaten" mice results in retinal degeneration.
Academic Article	Constant rate of steady-state self-antigen trafficking from skin to regional lymph nodes.
Academic Article	Effect of genetically determined immunodeficiency on epidermal dendritic cell populations in C57BL/6J mice.
Academic Article	Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.
Academic Article	Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger.
Academic Article	Effect of DNA-damaging agents on isolated spleen cells and lung fibroblasts from the mouse mutant "wasted," a putative animal model for ataxia-telangiectasia.
Academic Article	The mouse mutant "wasted": an animal model for ataxia-telangiectasia.
Academic Article	Outbreaks of Pneumocystis carinii pneumonia in colonies of immunodeficient mice.
Academic Article	Hematologic abnormalities of the immunodeficient mouse mutant, viable motheaten (mev).
Academic Article	The mouse mutation severe combined immune deficiency (scid) is on chromosome 16.
Academic Article	Non-germ-line elements (NGE) are present in the T cell receptor beta-chain genes isolated from the mutant mouse, motheaten (me/me).
Academic Article	NOD marrow stem cells adoptively transfer diabetes to resistant (NOD x NON)F1 mice.
Academic Article	The immunological mouse mutants nude (nu) and rhino (hrrh) generate cytotoxic effector cells following adoptive immunotherapy but fail to reject a transplanted tumor.
Academic Article	Adenosine deaminase activity in recipients of bone marrow from immunodeficient mice homozygous for the wasted mutation.
Academic Article	Genetically determined murine models of immunodeficiency.
Academic Article	Production of immunoglobulin isotypes by Ly-1+ B cells in viable motheaten and normal mice.
Academic Article	Defective lymphopoiesis in the bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. III. Normal mouse bone marrow cells enable mev/mev prothymocytes to generate thymocytes after intravenous transfer.
Academic Article	Effect of immunodeficiency on diabetogenesis in genetically diabetic (db/db) mice.
Academic Article	A serum-derived molecule from autoimmune viable motheaten mice potentiates the action of a B cell maturation factor.
Academic Article	B lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi.
Academic Article	Localization of prothymocytes from wild-type and viable motheaten mice following intravenous injection into irradiated adoptive recipients.
Academic Article	Ultrastructure of macrophages and dendritic cells in osteopetrosis (op) mutant mice lacking macrophage colony-stimulating factor (M-CSF/CSF-1) activity.
Academic Article	Effects of macrophage colony-stimulating factor (M-CSF) on the development, differentiation, and maturation of marginal metallophilic macrophages and marginal zone macrophages in the spleen of osteopetrosis (op) mutant mice lacking functional M-CSF activity.
Academic Article	The role of macrophage colony-stimulating factor in hepatic glucan-induced granuloma formation in the osteopetrosis mutant mouse defective in the production of macrophage colony-stimulating factor.
Concept	Mice, Mutant Strains
Academic Article	Generation of improved humanized mouse models for human infectious diseases.
Academic Article	Genes adapt to outsmart gene-targeting strategies in mutant mouse strains by skipping exons to reinitiate transcription and translation.

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Mice Mutant Strains