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Lipopolysaccharide-induced osteoclastogenesis in Src homology 2-domain phosphatase-1-deficient viable motheaten mice.
In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties.
Cancer stem cells are enriched in the side population cells in a mouse model of glioma.
Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate.
GLI1 regulates a novel neuropilin-2/a6?1 integrin based autocrine pathway that contributes to breast cancer initiation.
A pyrrolo-pyrimidine derivative targets human primary AML stem cells in vivo.
Distinct osteoclast precursors in the bone marrow and extramedullary organs characterized by responsiveness to Toll-like receptor ligands and TNF-alpha.
Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.
CD34+CD38+CD19+ as well as CD34+CD38-CD19+ cells are leukemia-initiating cells with self-renewal capacity in human B-precursor ALL.
Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.
Identification of therapeutic targets for quiescent, chemotherapy-resistant human leukemia stem cells.
Microenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt-?-catenin signaling.
Neoplastic Stem Cells
Regulated splicing of the a6 integrin cytoplasmic domain determines the fate of breast cancer stem cells.
c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.
A laminin 511 matrix is regulated by TAZ and functions as the ligand for the a6B?1 integrin to sustain breast cancer stem cells.
IMP3 promotes stem-like properties in triple-negative breast cancer by regulating SLUG.
P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer.
Neoplastic Stem Cells