| Item Type | Name |
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Academic Article
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Neural and skin cell-specific expression pattern conferred by steel factor regulatory sequence in transgenic mice.
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Academic Article
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Phenotype and function of human hematopoietic cells engrafting immune-deficient CB17-severe combined immunodeficiency mice and nonobese diabetic-severe combined immunodeficiency mice after transplantation of human cord blood mononuclear cells.
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Academic Article
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Neonatal changes of osteoclasts in osteopetrosis (op/op) mice defective in production of functional macrophage colony-stimulating factor (M-CSF) protein and effects of M-CSF on osteoclast development and differentiation.
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Academic Article
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Increased G-CSF responsiveness of bone marrow cells from hematopoietic cell phosphatase deficient viable motheaten mice.
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Academic Article
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Improved engraftment of human cord blood stem cells in NOD/LtSz-scid/scid mice after irradiation or multiple-day injections into unirradiated recipients.
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Academic Article
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Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris.
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Academic Article
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Engraftment and development of human CD34(+)-enriched cells from umbilical cord blood in NOD/LtSz-scid/scid mice.
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Academic Article
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LacZ and interleukin-3 expression in vivo after retroviral transduction of marrow-derived human osteogenic mesenchymal progenitors.
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Academic Article
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Mature human hematopoietic cells in donor bone marrow complicate interpretation of stem/progenitor cell assays in xenogeneic hematopoietic chimeras.
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Academic Article
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Follicular dendritic cell (FDC) precursors in primary lymphoid tissues.
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Academic Article
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SCID mouse models of human stem cell engraftment.
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Academic Article
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Effects of macrophage colony-stimulating factor on macrophages and their related cell populations in the osteopetrosis mouse defective in production of functional macrophage colony-stimulating factor protein.
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Academic Article
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Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4.
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Academic Article
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NZB mice exhibit a primary T cell defect in fetal thymic organ culture.
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Academic Article
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The plant lectin FRIL supports prolonged in vitro maintenance of quiescent human cord blood CD34(+)CD38(-/low)/SCID repopulating stem cells.
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Academic Article
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Variables to predict engraftment of umbilical cord blood into immunodeficient mice: usefulness of the non-obese diabetic--severe combined immunodeficient assay.
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Academic Article
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Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice.
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Academic Article
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Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand.
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Academic Article
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Age-related alterations in the lymphohematopoietic and B-lineage precursor populations in NZB mice.
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Academic Article
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Transgene expression of steel factor in the basal layer of epidermis promotes survival, proliferation, differentiation and migration of melanocyte precursors.
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Academic Article
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Establishment and characterization of pro-B cell lines from motheaten mutant mouse defective in SHP-1 protein tyrosine phosphatase.
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Academic Article
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Suppressive effects of monocytic cells and transforming growth factor-beta on natural killer cell differentiation in autoimmune viable motheaten mutant mice.
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Academic Article
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Continuous infusion of endostatin inhibits differentiation, mobilization, and clonogenic potential of endothelial cell progenitors.
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Academic Article
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Lipopolysaccharide-induced osteoclastogenesis in Src homology 2-domain phosphatase-1-deficient viable motheaten mice.
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Academic Article
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The soluble interleukin-6 (IL-6) receptor/IL-6 fusion protein enhances in vitro maintenance and proliferation of human CD34(+)CD38(-/low) cells capable of repopulating severe combined immunodeficiency mice.
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Academic Article
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An assay for human hematopoietic stem cells based on transplantation into nonobese diabetic recombination activating gene-null perforin-null mice.
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Academic Article
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Human cord blood--derived cells generate insulin-producing cells in vivo.
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Academic Article
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NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells.
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Academic Article
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Purified human hematopoietic stem cells contribute to the generation of cardiomyocytes through cell fusion.
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Academic Article
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Isolation of permanent clonal bone marrow stromal cell lines derived from "viable moth-eaten" and "severe combined immunodeficiency" mutant mice.
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Academic Article
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Effect of ex vivo cytokine treatment on human cord blood engraftment in NOD-scid mice.
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Academic Article
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beta2 microglobulin-deficient (B2m(null)) NOD/SCID mice are excellent recipients for studying human stem cell function.
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Academic Article
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Intramedullary and extramedullary B lymphopoiesis in osteopetrotic mice.
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Academic Article
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Previously undetected human hematopoietic cell populations with short-term repopulating activity selectively engraft NOD/SCID-beta2 microglobulin-null mice.
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Academic Article
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The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways.
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Academic Article
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The differentiative and regenerative properties of human hematopoietic stem/progenitor cells in NOD-SCID/IL2rgamma(null) mice.
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Academic Article
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Creation of "humanized" mice to study human immunity.
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Academic Article
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In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties.
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Academic Article
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Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment.
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Academic Article
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Cancer stem cells are enriched in the side population cells in a mouse model of glioma.
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Academic Article
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Relatively normal human lymphopoiesis but rapid turnover of newly formed B cells in transplanted nonobese diabetic/SCID mice.
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Academic Article
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Lymphohemopoiesis in culture is prevented by interaction with adherent bone marrow cells from mutant viable motheaten mice.
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Academic Article
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Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice.
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Academic Article
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In vivo selection of human embryonic stem cell-derived cells expressing methotrexate-resistant dihydrofolate reductase.
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Academic Article
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Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.
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Academic Article
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Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate.
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Academic Article
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Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice.
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Academic Article
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Defective in vitro migratory capacity of bone marrow cells from viable motheaten mice in response to normal thymus culture supernatants.
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Academic Article
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Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2r? null mice is enhanced by transgenic expression of membrane-bound human SCF.
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Academic Article
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Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation.
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Academic Article
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Antibody repertoires in humanized NOD-scid-IL2R?(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse.
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Academic Article
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In vitro and in vivo hematopoietic potential of human stem cells residing in muscle tissue.
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Academic Article
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Humanized mice for immune system investigation: progress, promise and challenges.
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Academic Article
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Increased frequency of pre-pro B cells in the bone marrow of New Zealand Black (NZB) mice: implications for a developmental block in B cell differentiation.
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Academic Article
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GLI1 regulates a novel neuropilin-2/a6?1 integrin based autocrine pathway that contributes to breast cancer initiation.
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Academic Article
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A pyrrolo-pyrimidine derivative targets human primary AML stem cells in vivo.
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Academic Article
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The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function.
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Academic Article
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Pleiotropic effects of deleterious alleles at the "motheaten" locus.
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Academic Article
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Regulation of human short-term repopulating cell (STRC) engraftment in NOD/SCID mice by host CD122+ cells.
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Academic Article
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Hematopoiesis and models of immunodeficiency.
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Academic Article
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NOD/LtSz-Rag1nullPfpnull mice: a new model system with increased levels of human peripheral leukocyte and hematopoietic stem-cell engraftment.
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Academic Article
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Distinct osteoclast precursors in the bone marrow and extramedullary organs characterized by responsiveness to Toll-like receptor ligands and TNF-alpha.
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Academic Article
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Hematopoietic stem cell function in motheaten mice.
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Academic Article
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Transgenic mice expressing either bovine growth hormone (bGH) or human GH releasing hormone (hGRH) have increased splenic progenitor cell colony formation and DNA synthesis in vitro and in vivo.
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Academic Article
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Emv30null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells.
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Academic Article
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Cellular origin of follicular dendritic cells.
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Academic Article
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Human cord blood- and bone marrow-derived CD34+ cells regenerate gastrointestinal epithelial cells.
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Academic Article
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Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells.
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Academic Article
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Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice.
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Academic Article
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Treatment and transfer of emphysema by a new bone marrow transplantation method from normal mice to Tsk mice and vice versa.
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Academic Article
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In vivo distribution of human adipose-derived mesenchymal stem cells in novel xenotransplantation models.
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Academic Article
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Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.
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Academic Article
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CD34+CD38+CD19+ as well as CD34+CD38-CD19+ cells are leukemia-initiating cells with self-renewal capacity in human B-precursor ALL.
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Academic Article
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A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function.
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Academic Article
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Expanded CD34+ human umbilical cord blood cells generate multiple lymphohematopoietic lineages in NOD-scid IL2rgamma(null) mice.
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Academic Article
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Humanized mice for the study of type 1 diabetes and beta cell function.
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Academic Article
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Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice.
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Academic Article
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TLR agonists prevent the establishment of allogeneic hematopoietic chimerism in mice treated with costimulation blockade.
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Academic Article
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Bioluminescent imaging demonstrates that transplanted human embryonic stem cell-derived CD34(+) cells preferentially develop into endothelial cells.
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Academic Article
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The mouse mutation "thrombocytopenia and cardiomyopathy" (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia.
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Academic Article
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Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.
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Academic Article
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Identification of therapeutic targets for quiescent, chemotherapy-resistant human leukemia stem cells.
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Academic Article
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Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection.
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Academic Article
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High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias.
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Academic Article
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Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids.
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Academic Article
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Hematologic abnormalities of the immunodeficient mouse mutant, viable motheaten (mev).
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Academic Article
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Humanized mice for the study of type 1 and type 2 diabetes.
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Academic Article
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Development of mature and functional human myeloid subsets in hematopoietic stem cell-engrafted NOD/SCID/IL2r?KO mice.
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Academic Article
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Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo.
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Academic Article
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Microenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt-?-catenin signaling.
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Academic Article
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Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming.
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Academic Article
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NOD marrow stem cells adoptively transfer diabetes to resistant (NOD x NON)F1 mice.
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Academic Article
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Engraftment of immune-deficient mice with primitive hematopoietic cells from beta-thalassemia and sickle cell anemia patients: implications for evaluating human gene therapy protocols.
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Academic Article
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Programmed differentiation of murine thymocytes during fetal thymus organ culture.
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Academic Article
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Localization of prothymocytes from wild-type and viable motheaten mice following intravenous injection into irradiated adoptive recipients.
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Academic Article
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Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene.
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Concept
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Neoplastic Stem Cells
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Concept
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Hematopoietic Stem Cell Transplantation
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Concept
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Mesenchymal Stem Cell Transplantation
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Concept
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Hematopoietic Stem Cell Mobilization
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Concept
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Lymphoid Progenitor Cells
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Concept
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Colony-Forming Units Assay
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Concept
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Stem Cells
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Concept
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Hematopoietic Stem Cells
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Concept
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Cord Blood Stem Cell Transplantation
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Concept
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Stem Cell Factor
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Concept
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Peripheral Blood Stem Cell Transplantation
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Concept
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Myeloid Progenitor Cells
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Concept
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Induced Pluripotent Stem Cells
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Concept
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Stem Cell Transplantation
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Concept
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Embryonic Stem Cells
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Concept
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Pluripotent Stem Cells
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Academic Article
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Regulated splicing of the a6 integrin cytoplasmic domain determines the fate of breast cancer stem cells.
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Academic Article
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c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.
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Academic Article
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Immunodeficient mouse model for human hematopoietic stem cell engraftment and immune system development.
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Academic Article
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A laminin 511 matrix is regulated by TAZ and functions as the ligand for the a6B?1 integrin to sustain breast cancer stem cells.
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Academic Article
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Identification of CD34+ and CD34- leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemia.
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Academic Article
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IMP3 promotes stem-like properties in triple-negative breast cancer by regulating SLUG.
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Academic Article
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P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer.
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Academic Article
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Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary.
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Academic Article
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Induction of WT1-specific human CD8+ T cells from human HSCs in HLA class I Tg NOD/SCID/IL2rgKO mice.
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Academic Article
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Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice.
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Academic Article
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Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells.
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Academic Article
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Cell-Extrinsic MHC Class I Molecule Engagement Augments Human NK Cell Education Programmed by Cell-Intrinsic MHC Class I.
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Academic Article
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Humanized mouse model of mast cell-mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis.
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Academic Article
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Improved B cell development in humanized NOD-scid IL2R?null mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3.
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Academic Article
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Analysis of parameters that affect human hematopoietic cell outputs in mutant c-kit-immunodeficient mice.
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Academic Article
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mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell-derived hematopoietic progenitors.
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Academic Article
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Human immune system development and survival of non-obese diabetic (NOD)-scid IL2r?(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells.
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Academic Article
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Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics.
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Academic Article
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Co-activation of macrophages and T cells contribute to chronic GVHD in human IL-6 transgenic humanised mouse model.
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Academic Article
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Mesenchymal stem cells: From regeneration to cancer.
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Academic Article
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Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells.
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Academic Article
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Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain.
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Academic Article
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Lung mesenchymal cells elicit lipid storage in neutrophils that fuel breast cancer lung metastasis.
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Academic Article
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A novel clinically relevant graft-versus-leukemia model in humanized mice.
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Academic Article
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Human Hematopoietic Stem Cell Engrafted IL-15 Transgenic NSG Mice Support Robust NK Cell Responses and Sustained HIV-1 Infection.
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Academic Article
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Long-Term Human Immune Reconstitution, T-Cell Development, and Immune Reactivity in Mice Lacking the Murine Major Histocompatibility Complex: Validation with Cellular and Gene Expression Profiles.
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