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Academic Article
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Cytokine gene expression in islets and thyroids of BB rats. IFN-gamma and IL-12p40 mRNA increase with age in both diabetic and insulin-treated nondiabetic BB rats.
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Academic Article
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Oral insulin does not prevent insulin-dependent diabetes mellitus in BB rats.
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Academic Article
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Anti-endothelial cell autoantibodies in BB rats with spontaneous and induced IDDM.
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Academic Article
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Tolerance to islet xenografts induced by dual manipulation of antigen presentation and co-stimulation.
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Academic Article
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Induction of insulin-dependent diabetes mellitus in PVG.RT1u rats.
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Academic Article
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The T cell marker RT6 in a rat model of autoimmune diabetes.
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Academic Article
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High frequency apoptosis of recent thymic emigrants in the liver of lymphopenic diabetes-prone BioBreeding rats.
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Academic Article
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Induction of immunological tolerance to islet allografts.
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Academic Article
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Induction of islet transplantation tolerance using donor specific transfusion and anti-CD154 monoclonal antibody.
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Academic Article
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Recapitulation of normal and abnormal BioBreeding rat T cell development in adult thymus organ culture.
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Academic Article
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NOD mice have a generalized defect in their response to transplantation tolerance induction.
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Academic Article
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Diabetes-prone and diabetes-resistant BB rats share a common major diabetes susceptibility locus, iddm4: additional evidence for a "universal autoimmunity locus" on rat chromosome 4.
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Academic Article
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The rat T-cell surface protein RT6 is associated with src family tyrosine kinases and generates an activation signal.
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Academic Article
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The BB/Wor rat and the balance hypothesis of autoimmunity.
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Academic Article
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Dietary cow's milk protein does not alter the frequency of diabetes in the BB rat.
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Academic Article
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Altered expression of diabetes in BB/Wor rats by exposure to viral pathogens.
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Academic Article
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NOD congenic mice genetically protected from autoimmune diabetes remain resistant to transplantation tolerance induction.
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Academic Article
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Induction of tolerance for islet transplantation for type 1 diabetes.
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Academic Article
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Non-major histocompatibility complex-linked diabetes susceptibility loci on chromosomes 4 and 13 in a backcross of the DP-BB/Wor rat to the WF rat.
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Academic Article
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Comparative mapping of rat Iddm4 to segments on HSA7 and MMU6.
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Academic Article
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Intravital dye-labeled diabetogenic rat T cells retain dye, home to the pancreas, and induce diabetes.
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Academic Article
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Islet allograft survival induced by costimulation blockade in NOD mice is controlled by allelic variants of Idd3.
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Academic Article
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Regulation of skin and islet allograft survival in mice treated with costimulation blockade is mediated by different CD4+ cell subsets and different mechanisms.
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Academic Article
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Insulin dependent diabetes mellitus hypothesis of autoimmunity.
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Academic Article
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TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats.
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Academic Article
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The rat diabetes susceptibility locus Iddm4 and at least one additional gene are required for autoimmune diabetes induced by viral infection.
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Academic Article
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Autoimmune destruction of islets transplanted into RT6-depleted diabetes-resistant BB/Wor rats.
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Academic Article
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Diabetes prone BB rats are severely deficient in natural killer T cells.
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Academic Article
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Allogeneic hematopoietic chimerism in mice treated with sublethal myeloablation and anti-CD154 antibody: absence of graft-versus-host disease, induction of skin allograft tolerance, and prevention of recurrent autoimmunity in islet-allografted NOD/Lt mice.
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Academic Article
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Costimulation and autoimmune diabetes in BB rats.
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Academic Article
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TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat.
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Academic Article
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Fetal thymi from diabetes-prone but not diabetes-resistant BB/Wor rats fail to generate mature ART2+ T-cells in organ culture.
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Academic Article
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Lack of systematically found insulin autoantibodies in spontaneously diabetic BB rats.
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Academic Article
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BB rat thymocytes cultured in the presence of islets lose their ability to transfer autoimmune diabetes.
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Academic Article
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Translating data from animal models into methods for preventing human autoimmune diabetes mellitus: caveat emptor and primum non nocere.
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Academic Article
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Autoimmune diabetes mellitus in the BB rat.
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Academic Article
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The effect of ciamexone on lymphocytic thyroiditis and insulin-dependent diabetes mellitus in the BB/Wor rat.
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Academic Article
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Genetic dissection reveals diabetes loci proximal to the gimap5 lymphopenia gene.
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Academic Article
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Virus-induced autoimmune diabetes in the LEW.1WR1 rat requires Iddm14 and a genetic locus proximal to the major histocompatibility complex.
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Academic Article
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Levels of Art2+ cells but not soluble Art2 protein correlate with expression of autoimmune diabetes in the BB rat.
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Academic Article
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Infection with viruses from several families triggers autoimmune diabetes in LEW*1WR1 rats: prevention of diabetes by maternal immunization.
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Academic Article
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Effects of irradiation on diabetes in the BB/Wor rat.
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Academic Article
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Islet cell transplantation tolerance.
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Academic Article
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The pathogenesis of autoimmune diabetes mellitus.
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Academic Article
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Implications of using hemoglobin A1C for diagnosing diabetes mellitus.
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Academic Article
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Prevention of type 1 diabetes in the rat with an allele-specific anti-T-cell receptor antibody: V?13 as a therapeutic target and biomarker.
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Academic Article
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Outcomes of a Latino community-based intervention for the prevention of diabetes: the Lawrence Latino Diabetes Prevention Project.
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Academic Article
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T-lymphocyte requirement for diabetes in RT6-depleted diabetes-resistant BB rats.
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Academic Article
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A420983, a novel, small molecule inhibitor of LCK prevents allograft rejection.
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Academic Article
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The iddm4 locus segregates with diabetes susceptibility in congenic WF.iddm4 rats.
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Academic Article
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Abnormal cardiac biochemistry in spontaneously diabetic Bio-Breeding/Worcester rat.
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Academic Article
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Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations.
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Academic Article
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Absence of RT6+ T cells in diabetes-prone biobreeding/Worcester rats is due to genetic and cell developmental defects.
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Academic Article
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Approaches to prevention and treatment of IDDM in animal models.
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Academic Article
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Absence of the RT-6 T cell subset in diabetes-prone BB/W rats.
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Academic Article
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Prothymocyte development in diabetes-prone BB rats: description of a defect that predisposes to immune abnormalities.
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Academic Article
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A pancreatic venular defect in the BB/Wor rat.
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Academic Article
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Genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice.
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Academic Article
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Irradiated lymphocytes do not adoptively transfer diabetes or prevent spontaneous disease in the BB/W rat.
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Academic Article
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Immunology of insulin-dependent diabetes mellitus.
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Academic Article
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Spleen cell transfusion in the Bio-Breeding/Worcester rat. Prevention of diabetes, major histocompatibility complex restriction, and long-term persistence of transfused cells.
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Academic Article
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Hormonal and environmental factors in the pathogenesis of BB rat diabetes.
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Academic Article
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Surgery in the diabetic patient.
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Academic Article
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Failure to transfer insulitis to athymic recipients using BB/W rat lymphoid tissue transplants.
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Academic Article
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Total lymphoid irradiation prevents diabetes mellitus in the Bio-Breeding/Worcester (BB/W) rat.
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Academic Article
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Animal models of diabetes.
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Academic Article
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Lymphocyte transfusions prevent diabetes in the Bio-Breeding/Worcester rat.
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Academic Article
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Insulin treatment prevents diabetes mellitus but not thyroiditis in RT6-depleted diabetes resistant BB/Wor rats.
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Academic Article
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An RT6a gene is transcribed and translated in lymphopenic diabetes-prone BB rats.
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Academic Article
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Adoptive transfer of autoimmune diabetes mellitus to athymic rats: synergy of CD4+ and CD8+ T cells and prevention by RT6+ T cells.
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Academic Article
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Loss of RT6 message and most circulating T cells after thymectomy of diabetes prone BB rats.
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Academic Article
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Evidence that intrathymic islet transplantation does not prevent diabetes or subsequent islet graft destruction in RT6-depleted, diabetes-resistant BioBreeding/Worcester rats.
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Academic Article
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T lymphocytes capable of activating endothelial cells in vitro are present in rats with autoimmune diabetes.
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Academic Article
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Deficiencies in gut NK cell number and function precede diabetes onset in BB rats.
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Academic Article
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Prolonged survival of neonatal porcine islet xenografts in mice treated with a donor-specific transfusion and anti-CD154 antibody.
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Academic Article
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Rat models of type 1 diabetes: genetics, environment, and autoimmunity.
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Academic Article
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Autoimmune diabetes and resistance to xenograft transplantation tolerance in NOD mice.
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Academic Article
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A regulatory CD4+ T cell subset in the BB rat model of autoimmune diabetes expresses neither CD25 nor Foxp3.
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Academic Article
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Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity.
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Academic Article
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Refinement of the Iddm4 diabetes susceptibility locus reveals TCRVbeta4 as a candidate gene.
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Academic Article
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A novel susceptibility locus on rat chromosome 8 affects spontaneous but not experimentally induced type 1 diabetes.
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Academic Article
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Biochemical studies of RT6 alloantigens in BB/Wor and normal rats. Evidence for intact unexpressed RT6a structural gene in diabetes-prone BB rats.
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Academic Article
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Adoptive transfer of autoimmune diabetes and thyroiditis to athymic rats.
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Academic Article
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Prevention of diabetes in the BB rat by essential fatty acid deficiency. Relationship between physiological and biochemical changes.
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Academic Article
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The BB rat as a model of human insulin-dependent diabetes mellitus.
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Academic Article
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Plasma from BB/Wor rats increases insulin secretion by perfused rat pancreas.
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Academic Article
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Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus.
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Academic Article
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Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat.
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Academic Article
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CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells.
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Academic Article
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Haptoglobin as an early serum biomarker of virus-induced autoimmune type 1 diabetes in biobreeding diabetes resistant and LEW1.WR1 rats.
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Academic Article
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Prevention of diabetes in BB/Wor rat by single transfusion of spleen cells. Parameters that affect degree of protection.
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Academic Article
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Transfusions enriched for W3/25+ helper/inducer T lymphocytes prevent spontaneous diabetes in the BB/W rat.
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Academic Article
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Temporal induction of immunoregulatory processes coincides with age-dependent resistance to viral-induced type 1 diabetes.
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Academic Article
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Regulatory T cell control of autoimmune destruction of beta cells in the BB rat.
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Academic Article
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Role of host immune system in BB/Wor rat. Predisposition to diabetes resides in bone marrow.
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Academic Article
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The BB rat.
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Academic Article
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Speculations on etiology of diabetes mellitus. Tumbler hypothesis.
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Academic Article
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Depletion of RT6.1+ T lymphocytes induces diabetes in resistant biobreeding/Worcester (BB/W) rats.
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Academic Article
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Effect of interleukin-2 on diabetes in the BB/Wor rat.
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Academic Article
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Diabetes in the Bio-Breeding/Worcester rat. Induction and acceleration by spleen cell-conditioned media.
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Academic Article
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Transfusions of whole blood prevent spontaneous diabetes mellitus in the BB/W rat.
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Academic Article
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Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand.
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Academic Article
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DR-BB rat thymus contains thymocyte populations predisposed to autoreactivity.
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Academic Article
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Human autoimmune diabetes mellitus: lessons from BB rats and NOD mice--Caveat emptor.
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Academic Article
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Cytolysin gene expression in the islets of diabetic BioBreeding/Worcester rats.
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Academic Article
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Pancreas-specific venular labeling by monastral blue B in the BB rat: modulation by prostaglandins and their inhibitors.
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Concept
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Diabetes Mellitus
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Concept
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Diabetes Mellitus, Type 2
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Concept
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Diabetes Mellitus, Type 1
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Concept
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Diabetes Mellitus, Experimental
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Academic Article
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Autoantigen-induced focusing of V?13+ T cells precedes onset of autoimmune diabetes in the LEW.1WR1 rat.
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Academic Article
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Diubiquitin (Ubd) is a susceptibility gene for virus-triggered autoimmune diabetes in rats.
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Academic Article
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Management status and its predictive factors in patients with type 2 diabetes in China: A Nationwide Multicenter Study: A Nationwide Multicenter Study.
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Academic Article
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A Critical Role for the Type I Interferon Receptor in Virus-Induced Autoimmune Diabetes in Rats.
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Academic Article
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Autoimmunity after islet-cell allotransplantation.
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Academic Article
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Genetic Variation Within the HLA-DRA1 Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes.
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Academic Article
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Comparing the effects of 6 months aerobic exercise and resistance training on metabolic control and ?-cell function in Chinese patients with prediabetes: A multicenter randomized controlled trial.
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Academic Article
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The Vbeta13 T Cell Receptor Monoclonal Antibody Reduces Hyaluronan and CD68+, CD3+, and CD8+ Cell Infiltrations to Delay Diabetes in Congenic BB DRLyp/Lyp Rats.
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Academic Article
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T Cell Receptor Genotype and Ubash3a Determine Susceptibility to Rat Autoimmune Diabetes.
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