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One or more keywords matched the following items that are connected to Mordes, John
Item TypeName
Academic Article Cytokine gene expression in islets and thyroids of BB rats. IFN-gamma and IL-12p40 mRNA increase with age in both diabetic and insulin-treated nondiabetic BB rats.
Academic Article Oral insulin does not prevent insulin-dependent diabetes mellitus in BB rats.
Academic Article Ontogeny and immunohistochemical localization of thymus-dependent and thymus-independent RT6+ cells in the rat.
Academic Article Anti-endothelial cell autoantibodies in BB rats with spontaneous and induced IDDM.
Academic Article Tolerance to islet xenografts induced by dual manipulation of antigen presentation and co-stimulation.
Academic Article Induction of insulin-dependent diabetes mellitus in PVG.RT1u rats.
Academic Article The T cell marker RT6 in a rat model of autoimmune diabetes.
Academic Article High frequency apoptosis of recent thymic emigrants in the liver of lymphopenic diabetes-prone BioBreeding rats.
Academic Article Induction of immunological tolerance to islet allografts.
Academic Article Rat RT6.2 and mouse Rt6 locus 1 are NAD+: arginine ADP ribosyltransferases with auto-ADP ribosylation activity.
Academic Article Induction of islet transplantation tolerance using donor specific transfusion and anti-CD154 monoclonal antibody.
Academic Article Prolonged skin allograft survival in mice treated with Flt3-ligand-induced dendritic cells and anti-CD154 monoclonal antibody.
Academic Article Recapitulation of normal and abnormal BioBreeding rat T cell development in adult thymus organ culture.
Academic Article Diabetes-prone and diabetes-resistant BB rats share a common major diabetes susceptibility locus, iddm4: additional evidence for a "universal autoimmunity locus" on rat chromosome 4.
Academic Article Treatment of allograft recipients with donor-specific transfusion and anti-CD154 antibody leads to deletion of alloreactive CD8+ T cells and prolonged graft survival in a CTLA4-dependent manner.
Academic Article Virus-induced abrogation of transplantation tolerance induced by donor-specific transfusion and anti-CD154 antibody.
Academic Article The rat T-cell surface protein RT6 is associated with src family tyrosine kinases and generates an activation signal.
Academic Article The BB/Wor rat and the balance hypothesis of autoimmunity.
Academic Article Viral infection abrogates CD8(+) T-cell deletion induced by costimulation blockade.
Academic Article Characterization of mouse Rt6.1 NAD:arginine ADP-ribosyltransferase.
Academic Article Nicotinamide adenine dinucleotide (NAD) and its metabolites inhibit T lymphocyte proliferation: role of cell surface NAD glycohydrolase and pyrophosphatase activities.
Academic Article Expression in BALB/c and C57BL/6 mice of Rt6-1 and Rt6-2 ADP-ribosyltransferases that differ in enzymatic activity: C57BL/6 Rt6-1 is a natural transferase knockout.
Academic Article Morphological and physiological characteristics of pancreas-specific venular permeability induced by Monastral blue B.
Academic Article Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.
Academic Article Altered expression of diabetes in BB/Wor rats by exposure to viral pathogens.
Academic Article Improved skin allograft tolerance induced by treatment with donor splenocytes and an extended course of anti-CD154 monoclonal antibody.
Academic Article NOD congenic mice genetically protected from autoimmune diabetes remain resistant to transplantation tolerance induction.
Academic Article Blockade of CD40-mediated signaling is sufficient for inducing islet but not skin transplantation tolerance.
Academic Article Ian4 is required for mitochondrial integrity and T cell survival.
Academic Article CTLA4 signals are required to optimally induce allograft tolerance with combined donor-specific transfusion and anti-CD154 monoclonal antibody treatment.
Academic Article Intravital dye-labeled diabetogenic rat T cells retain dye, home to the pancreas, and induce diabetes.
Academic Article The RT6 (Art2) family of ADP-ribosyltransferases in rat and mouse.
Academic Article A new isolation method for rat intraepithelial lymphocytes.
Academic Article Regulation of skin and islet allograft survival in mice treated with costimulation blockade is mediated by different CD4+ cell subsets and different mechanisms.
Academic Article Early growth response gene-2, a zinc-finger transcription factor, is required for full induction of clonal anergy in CD4+ T cells.
Academic Article Evaluation of donor-specific transfusion sources: unique failure of bone marrow cells to induce prolonged skin allograft survival with anti-CD154 monoclonal antibody.
Academic Article The rat diabetes susceptibility locus Iddm4 and at least one additional gene are required for autoimmune diabetes induced by viral infection.
Academic Article Autoimmune destruction of islets transplanted into RT6-depleted diabetes-resistant BB/Wor rats.
Academic Article Diabetes prone BB rats are severely deficient in natural killer T cells.
Academic Article Rat xenograft survival in mice treated with donor-specific transfusion and anti-CD154 antibody is enhanced by elimination of host CD4+ cells.
Academic Article Costimulatory blockade induces hyporesponsiveness in T cells that recognize alloantigen via indirect antigen presentation.
Academic Article TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat.
Academic Article Fetal thymi from diabetes-prone but not diabetes-resistant BB/Wor rats fail to generate mature ART2+ T-cells in organ culture.
Academic Article Intrinsic cytotoxicity of natural killer cells to pancreatic islets in vitro.
Academic Article BB rat thymocytes cultured in the presence of islets lose their ability to transfer autoimmune diabetes.
Academic Article Different mechanisms control peripheral and central tolerance in hematopoietic chimeric mice.
Academic Article Type 1 IFN mediates cross-talk between innate and adaptive immunity that abrogates transplantation tolerance.
Academic Article An atypical population of NK cells that spontaneously secrete IFN-gamma and IL-4 is present in the intraepithelial lymphoid compartment of the rat.
Academic Article Depletion of the programmed death-1 receptor completely reverses established clonal anergy in CD4(+) T lymphocytes via an interleukin-2-dependent mechanism.
Academic Article Levels of Art2+ cells but not soluble Art2 protein correlate with expression of autoimmune diabetes in the BB rat.
Academic Article Skin allograft maintenance in a new synchimeric model system of tolerance.
Academic Article Effects of irradiation on diabetes in the BB/Wor rat.
Academic Article Islet cell transplantation tolerance.
Academic Article The pathogenesis of autoimmune diabetes mellitus.
Academic Article Implications of using hemoglobin A1C for diagnosing diabetes mellitus.
Academic Article Prevention of type 1 diabetes in the rat with an allele-specific anti-T-cell receptor antibody: V?13 as a therapeutic target and biomarker.
Academic Article Viral abrogation of stem cell transplantation tolerance causes graft rejection and host death by different mechanisms.
Academic Article T-lymphocyte requirement for diabetes in RT6-depleted diabetes-resistant BB rats.
Academic Article Type 1 cytokines polarize thymocytes during T cell development in adult thymus organ cultures.
Academic Article Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations.
Academic Article Absence of RT6+ T cells in diabetes-prone biobreeding/Worcester rats is due to genetic and cell developmental defects.
Academic Article Absence of the RT-6 T cell subset in diabetes-prone BB/W rats.
Academic Article Prothymocyte development in diabetes-prone BB rats: description of a defect that predisposes to immune abnormalities.
Academic Article Genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice.
Academic Article Irradiated lymphocytes do not adoptively transfer diabetes or prevent spontaneous disease in the BB/W rat.
Academic Article Immunology of insulin-dependent diabetes mellitus.
Academic Article Hematopoietic chimerism and central tolerance created by peripheral-tolerance induction without myeloablative conditioning.
Academic Article Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice.
Academic Article Total lymphoid irradiation prevents diabetes mellitus in the Bio-Breeding/Worcester (BB/W) rat.
Academic Article Lymphocyte transfusions prevent diabetes in the Bio-Breeding/Worcester rat.
Academic Article Insulin treatment prevents diabetes mellitus but not thyroiditis in RT6-depleted diabetes resistant BB/Wor rats.
Academic Article Recapitulation of normal and abnormal BB rat immune system development in scid mouse/rat lymphohemopoietic chimeras.
Academic Article High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to human immunodeficiency virus type 1 infection in NOD/LtSz-scid/scid mice.
Academic Article An RT6a gene is transcribed and translated in lymphopenic diabetes-prone BB rats.
Academic Article Adoptive transfer of autoimmune diabetes mellitus to athymic rats: synergy of CD4+ and CD8+ T cells and prevention by RT6+ T cells.
Academic Article Loss of RT6 message and most circulating T cells after thymectomy of diabetes prone BB rats.
Academic Article Evidence that intrathymic islet transplantation does not prevent diabetes or subsequent islet graft destruction in RT6-depleted, diabetes-resistant BioBreeding/Worcester rats.
Academic Article T lymphocytes capable of activating endothelial cells in vitro are present in rats with autoimmune diabetes.
Academic Article Deficiencies in gut NK cell number and function precede diabetes onset in BB rats.
Academic Article Prolonged survival of neonatal porcine islet xenografts in mice treated with a donor-specific transfusion and anti-CD154 antibody.
Academic Article TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts.
Academic Article ART2, a T cell surface mono-ADP-ribosyltransferase, generates extracellular poly(ADP-ribose).
Academic Article A regulatory CD4+ T cell subset in the BB rat model of autoimmune diabetes expresses neither CD25 nor Foxp3.
Academic Article Biochemical studies of RT6 alloantigens in BB/Wor and normal rats. Evidence for intact unexpressed RT6a structural gene in diabetes-prone BB rats.
Academic Article Adoptive transfer of autoimmune diabetes and thyroiditis to athymic rats.
Academic Article Protein kinase C signaling during T cell activation induces the endoplasmic reticulum stress response.
Academic Article Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat.
Academic Article CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells.
Academic Article Prevention of diabetes in BB/Wor rat by single transfusion of spleen cells. Parameters that affect degree of protection.
Academic Article Transfusions enriched for W3/25+ helper/inducer T lymphocytes prevent spontaneous diabetes in the BB/W rat.
Academic Article Regulatory T cell control of autoimmune destruction of beta cells in the BB rat.
Academic Article Depletion of RT6.1+ T lymphocytes induces diabetes in resistant biobreeding/Worcester (BB/W) rats.
Academic Article Effect of interleukin-2 on diabetes in the BB/Wor rat.
Academic Article Diabetes in the Bio-Breeding/Worcester rat. Induction and acceleration by spleen cell-conditioned media.
Academic Article Pancreatic polypeptide causes diarrhea and weight loss in obese mice but not in lean littermates.
Academic Article Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand.
Academic Article DR-BB rat thymus contains thymocyte populations predisposed to autoreactivity.
Academic Article Thymic epithelial defects and predisposition to autoimmune disease in BB rats.
Academic Article The RT6 rat lymphocyte alloantigen circulates in soluble form.
Academic Article Cytolysin gene expression in the islets of diabetic BioBreeding/Worcester rats.
Academic Article Pancreas-specific venular labeling by monastral blue B in the BB rat: modulation by prostaglandins and their inhibitors.
Academic Article High stimulatory activity of dendritic cells from diabetes-prone BioBreeding/Worcester rats exposed to macrophage-derived factors.
Concept T-Lymphocytes, Cytotoxic
Concept CD8-Positive T-Lymphocytes
Concept Lymphocyte Count
Concept Sensitivity and Specificity
Concept Antigens, Differentiation, T-Lymphocyte
Concept T-Lymphocytes, Helper-Inducer
Concept T-Lymphocytes, Regulatory
Concept Specific Pathogen-Free Organisms
Concept T-Lymphocyte Subsets
Concept Epitopes, T-Lymphocyte
Concept Organ Specificity
Concept Species Specificity
Concept T-Lymphocytes
Concept Lymphocyte Culture Test, Mixed
Concept Lymphocytes
Concept Lymphocyte Activation
Concept Lymphocyte Depletion
Concept Antibody Specificity
Concept CD4-Positive T-Lymphocytes
Concept B-Lymphocytes
Concept Lymphocyte Subsets
Concept Lymphocyte Transfusion
Academic Article Autoantigen-induced focusing of V?13+ T cells precedes onset of autoimmune diabetes in the LEW.1WR1 rat.
Academic Article The Vbeta13 T Cell Receptor Monoclonal Antibody Reduces Hyaluronan and CD68+, CD3+, and CD8+ Cell Infiltrations to Delay Diabetes in Congenic BB DRLyp/Lyp Rats.
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