| Item Type | Name |
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Academic Article
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Cytokine gene expression in islets and thyroids of BB rats. IFN-gamma and IL-12p40 mRNA increase with age in both diabetic and insulin-treated nondiabetic BB rats.
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Academic Article
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Oral insulin does not prevent insulin-dependent diabetes mellitus in BB rats.
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Academic Article
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Ontogeny and immunohistochemical localization of thymus-dependent and thymus-independent RT6+ cells in the rat.
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Academic Article
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Anti-endothelial cell autoantibodies in BB rats with spontaneous and induced IDDM.
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Academic Article
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Tolerance to islet xenografts induced by dual manipulation of antigen presentation and co-stimulation.
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Academic Article
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Induction of insulin-dependent diabetes mellitus in PVG.RT1u rats.
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Academic Article
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The T cell marker RT6 in a rat model of autoimmune diabetes.
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Academic Article
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High frequency apoptosis of recent thymic emigrants in the liver of lymphopenic diabetes-prone BioBreeding rats.
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Academic Article
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Induction of immunological tolerance to islet allografts.
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Academic Article
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Rat RT6.2 and mouse Rt6 locus 1 are NAD+: arginine ADP ribosyltransferases with auto-ADP ribosylation activity.
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Academic Article
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Induction of islet transplantation tolerance using donor specific transfusion and anti-CD154 monoclonal antibody.
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Academic Article
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Prolonged skin allograft survival in mice treated with Flt3-ligand-induced dendritic cells and anti-CD154 monoclonal antibody.
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Academic Article
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Recapitulation of normal and abnormal BioBreeding rat T cell development in adult thymus organ culture.
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Academic Article
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Diabetes-prone and diabetes-resistant BB rats share a common major diabetes susceptibility locus, iddm4: additional evidence for a "universal autoimmunity locus" on rat chromosome 4.
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Academic Article
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Treatment of allograft recipients with donor-specific transfusion and anti-CD154 antibody leads to deletion of alloreactive CD8+ T cells and prolonged graft survival in a CTLA4-dependent manner.
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Academic Article
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Virus-induced abrogation of transplantation tolerance induced by donor-specific transfusion and anti-CD154 antibody.
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Academic Article
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The rat T-cell surface protein RT6 is associated with src family tyrosine kinases and generates an activation signal.
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Academic Article
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The BB/Wor rat and the balance hypothesis of autoimmunity.
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Academic Article
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Viral infection abrogates CD8(+) T-cell deletion induced by costimulation blockade.
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Academic Article
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Characterization of mouse Rt6.1 NAD:arginine ADP-ribosyltransferase.
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Academic Article
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Nicotinamide adenine dinucleotide (NAD) and its metabolites inhibit T lymphocyte proliferation: role of cell surface NAD glycohydrolase and pyrophosphatase activities.
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Academic Article
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Expression in BALB/c and C57BL/6 mice of Rt6-1 and Rt6-2 ADP-ribosyltransferases that differ in enzymatic activity: C57BL/6 Rt6-1 is a natural transferase knockout.
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Academic Article
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Morphological and physiological characteristics of pancreas-specific venular permeability induced by Monastral blue B.
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Academic Article
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Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.
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Academic Article
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Altered expression of diabetes in BB/Wor rats by exposure to viral pathogens.
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Academic Article
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Improved skin allograft tolerance induced by treatment with donor splenocytes and an extended course of anti-CD154 monoclonal antibody.
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Academic Article
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NOD congenic mice genetically protected from autoimmune diabetes remain resistant to transplantation tolerance induction.
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Academic Article
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Blockade of CD40-mediated signaling is sufficient for inducing islet but not skin transplantation tolerance.
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Academic Article
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Ian4 is required for mitochondrial integrity and T cell survival.
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Academic Article
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CTLA4 signals are required to optimally induce allograft tolerance with combined donor-specific transfusion and anti-CD154 monoclonal antibody treatment.
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Academic Article
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Intravital dye-labeled diabetogenic rat T cells retain dye, home to the pancreas, and induce diabetes.
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Academic Article
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The RT6 (Art2) family of ADP-ribosyltransferases in rat and mouse.
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Academic Article
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A new isolation method for rat intraepithelial lymphocytes.
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Academic Article
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Regulation of skin and islet allograft survival in mice treated with costimulation blockade is mediated by different CD4+ cell subsets and different mechanisms.
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Academic Article
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Early growth response gene-2, a zinc-finger transcription factor, is required for full induction of clonal anergy in CD4+ T cells.
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Academic Article
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Evaluation of donor-specific transfusion sources: unique failure of bone marrow cells to induce prolonged skin allograft survival with anti-CD154 monoclonal antibody.
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Academic Article
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The rat diabetes susceptibility locus Iddm4 and at least one additional gene are required for autoimmune diabetes induced by viral infection.
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Academic Article
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Autoimmune destruction of islets transplanted into RT6-depleted diabetes-resistant BB/Wor rats.
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Academic Article
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Diabetes prone BB rats are severely deficient in natural killer T cells.
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Academic Article
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Rat xenograft survival in mice treated with donor-specific transfusion and anti-CD154 antibody is enhanced by elimination of host CD4+ cells.
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Academic Article
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Costimulatory blockade induces hyporesponsiveness in T cells that recognize alloantigen via indirect antigen presentation.
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Academic Article
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TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat.
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Academic Article
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Fetal thymi from diabetes-prone but not diabetes-resistant BB/Wor rats fail to generate mature ART2+ T-cells in organ culture.
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Academic Article
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Intrinsic cytotoxicity of natural killer cells to pancreatic islets in vitro.
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Academic Article
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BB rat thymocytes cultured in the presence of islets lose their ability to transfer autoimmune diabetes.
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Academic Article
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Different mechanisms control peripheral and central tolerance in hematopoietic chimeric mice.
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Academic Article
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Type 1 IFN mediates cross-talk between innate and adaptive immunity that abrogates transplantation tolerance.
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Academic Article
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An atypical population of NK cells that spontaneously secrete IFN-gamma and IL-4 is present in the intraepithelial lymphoid compartment of the rat.
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Academic Article
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Depletion of the programmed death-1 receptor completely reverses established clonal anergy in CD4(+) T lymphocytes via an interleukin-2-dependent mechanism.
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Academic Article
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Levels of Art2+ cells but not soluble Art2 protein correlate with expression of autoimmune diabetes in the BB rat.
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Academic Article
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Skin allograft maintenance in a new synchimeric model system of tolerance.
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Academic Article
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Effects of irradiation on diabetes in the BB/Wor rat.
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Academic Article
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Islet cell transplantation tolerance.
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Academic Article
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The pathogenesis of autoimmune diabetes mellitus.
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Academic Article
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Implications of using hemoglobin A1C for diagnosing diabetes mellitus.
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Academic Article
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Prevention of type 1 diabetes in the rat with an allele-specific anti-T-cell receptor antibody: V?13 as a therapeutic target and biomarker.
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Academic Article
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Viral abrogation of stem cell transplantation tolerance causes graft rejection and host death by different mechanisms.
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Academic Article
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T-lymphocyte requirement for diabetes in RT6-depleted diabetes-resistant BB rats.
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Academic Article
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Type 1 cytokines polarize thymocytes during T cell development in adult thymus organ cultures.
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Academic Article
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Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations.
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Academic Article
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Absence of RT6+ T cells in diabetes-prone biobreeding/Worcester rats is due to genetic and cell developmental defects.
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Academic Article
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Absence of the RT-6 T cell subset in diabetes-prone BB/W rats.
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Academic Article
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Prothymocyte development in diabetes-prone BB rats: description of a defect that predisposes to immune abnormalities.
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Academic Article
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Genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice.
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Academic Article
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Irradiated lymphocytes do not adoptively transfer diabetes or prevent spontaneous disease in the BB/W rat.
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Academic Article
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Immunology of insulin-dependent diabetes mellitus.
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Academic Article
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Hematopoietic chimerism and central tolerance created by peripheral-tolerance induction without myeloablative conditioning.
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Academic Article
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Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice.
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Academic Article
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Total lymphoid irradiation prevents diabetes mellitus in the Bio-Breeding/Worcester (BB/W) rat.
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Academic Article
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Lymphocyte transfusions prevent diabetes in the Bio-Breeding/Worcester rat.
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Academic Article
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Insulin treatment prevents diabetes mellitus but not thyroiditis in RT6-depleted diabetes resistant BB/Wor rats.
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Academic Article
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Recapitulation of normal and abnormal BB rat immune system development in scid mouse/rat lymphohemopoietic chimeras.
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Academic Article
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High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to human immunodeficiency virus type 1 infection in NOD/LtSz-scid/scid mice.
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Academic Article
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An RT6a gene is transcribed and translated in lymphopenic diabetes-prone BB rats.
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Academic Article
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Adoptive transfer of autoimmune diabetes mellitus to athymic rats: synergy of CD4+ and CD8+ T cells and prevention by RT6+ T cells.
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Academic Article
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Loss of RT6 message and most circulating T cells after thymectomy of diabetes prone BB rats.
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Academic Article
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Evidence that intrathymic islet transplantation does not prevent diabetes or subsequent islet graft destruction in RT6-depleted, diabetes-resistant BioBreeding/Worcester rats.
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Academic Article
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T lymphocytes capable of activating endothelial cells in vitro are present in rats with autoimmune diabetes.
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Academic Article
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Deficiencies in gut NK cell number and function precede diabetes onset in BB rats.
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Academic Article
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Prolonged survival of neonatal porcine islet xenografts in mice treated with a donor-specific transfusion and anti-CD154 antibody.
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Academic Article
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TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts.
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Academic Article
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ART2, a T cell surface mono-ADP-ribosyltransferase, generates extracellular poly(ADP-ribose).
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Academic Article
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A regulatory CD4+ T cell subset in the BB rat model of autoimmune diabetes expresses neither CD25 nor Foxp3.
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Academic Article
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Biochemical studies of RT6 alloantigens in BB/Wor and normal rats. Evidence for intact unexpressed RT6a structural gene in diabetes-prone BB rats.
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Academic Article
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Adoptive transfer of autoimmune diabetes and thyroiditis to athymic rats.
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Academic Article
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Protein kinase C signaling during T cell activation induces the endoplasmic reticulum stress response.
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Academic Article
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Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat.
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Academic Article
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CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells.
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Academic Article
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Prevention of diabetes in BB/Wor rat by single transfusion of spleen cells. Parameters that affect degree of protection.
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Academic Article
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Transfusions enriched for W3/25+ helper/inducer T lymphocytes prevent spontaneous diabetes in the BB/W rat.
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Academic Article
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Regulatory T cell control of autoimmune destruction of beta cells in the BB rat.
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Academic Article
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Depletion of RT6.1+ T lymphocytes induces diabetes in resistant biobreeding/Worcester (BB/W) rats.
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Academic Article
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Effect of interleukin-2 on diabetes in the BB/Wor rat.
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Academic Article
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Diabetes in the Bio-Breeding/Worcester rat. Induction and acceleration by spleen cell-conditioned media.
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Academic Article
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Pancreatic polypeptide causes diarrhea and weight loss in obese mice but not in lean littermates.
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Academic Article
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Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand.
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Academic Article
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DR-BB rat thymus contains thymocyte populations predisposed to autoreactivity.
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Academic Article
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Thymic epithelial defects and predisposition to autoimmune disease in BB rats.
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Academic Article
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The RT6 rat lymphocyte alloantigen circulates in soluble form.
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Academic Article
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Cytolysin gene expression in the islets of diabetic BioBreeding/Worcester rats.
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Academic Article
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Pancreas-specific venular labeling by monastral blue B in the BB rat: modulation by prostaglandins and their inhibitors.
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Academic Article
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High stimulatory activity of dendritic cells from diabetes-prone BioBreeding/Worcester rats exposed to macrophage-derived factors.
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Concept
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T-Lymphocytes, Cytotoxic
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Concept
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CD8-Positive T-Lymphocytes
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Concept
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Lymphocyte Count
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Concept
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Sensitivity and Specificity
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Concept
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Antigens, Differentiation, T-Lymphocyte
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Concept
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T-Lymphocytes, Helper-Inducer
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Concept
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T-Lymphocytes, Regulatory
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Concept
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Specific Pathogen-Free Organisms
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Concept
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T-Lymphocyte Subsets
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Concept
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Epitopes, T-Lymphocyte
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Concept
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Organ Specificity
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Concept
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Species Specificity
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Concept
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T-Lymphocytes
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Concept
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Lymphocyte Culture Test, Mixed
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Concept
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Lymphocytes
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Concept
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Lymphocyte Activation
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Concept
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Lymphocyte Depletion
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Concept
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Antibody Specificity
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Concept
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CD4-Positive T-Lymphocytes
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Concept
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B-Lymphocytes
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Concept
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Lymphocyte Subsets
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Concept
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Lymphocyte Transfusion
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Academic Article
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Autoantigen-induced focusing of V?13+ T cells precedes onset of autoimmune diabetes in the LEW.1WR1 rat.
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Academic Article
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The Vbeta13 T Cell Receptor Monoclonal Antibody Reduces Hyaluronan and CD68+, CD3+, and CD8+ Cell Infiltrations to Delay Diabetes in Congenic BB DRLyp/Lyp Rats.
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