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Schrader, Carol
One or more keywords matched the following items that are connected to Schrader, Carol
Item TypeName
Academic Article Inducible DNA breaks in Ig S regions are dependent on AID and UNG.
Academic Article Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair.
Academic Article AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].
Academic Article Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination.
Academic Article Mechanism and regulation of class switch recombination.
Academic Article p53 represses class switch recombination to IgG2a through its antioxidant function.
Concept Cytidine Deaminase
Academic Article ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination.
Academic Article Apurinic/apyrimidinic endonuclease 2 regulates the expansion of germinal centers by protecting against activation-induced cytidine deaminase-independent DNA damage in B cells.
Academic Article Mismatch repair proteins and AID activity are required for the dominant negative function of C-terminally deleted AID in class switching.
Academic Article IgH chain class switch recombination: mechanism and regulation.
Academic Article Response to comment on "IgH chain class switch recombination: mechanism and regulation".
Academic Article Nbs1 ChIP-Seq Identifies Off-Target DNA Double-Strand Breaks Induced by AID in Activated Splenic B Cells.
Academic Article Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination.
Academic Article APE2 Promotes AID-Dependent Somatic Hypermutation in Primary B Cell Cultures That Is Suppressed by APE1.
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  • Cytidine Deaminase