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Schrader, Carol
One or more keywords matched the following items that are connected to Schrader, Carol
Item TypeName
Academic Article The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA.
Academic Article Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions.
Academic Article Inducible DNA breaks in Ig S regions are dependent on AID and UNG.
Academic Article Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair.
Academic Article APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination.
Academic Article The roles of APE1, APE2, DNA polymerase beta and mismatch repair in creating S region DNA breaks during antibody class switch.
Academic Article Reassessment of the role of Mut S homolog 5 in Ig class switch recombination shows lack of involvement in cis- and trans-switching.
Academic Article Class switch recombination efficiency and junction microhomology patterns in Msh2-, Mlh1-, and Exo1-deficient mice depend on the presence of mu switch region tandem repeats.
Academic Article The role of Apex2 in class-switch recombination of immunoglobulin genes.
Academic Article Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions.
Academic Article AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].
Academic Article The DNA glycosylases Ogg1 and Nth1 do not contribute to Ig class switching in activated mouse splenic B cells.
Academic Article Mlh1 can function in antibody class switch recombination independently of Msh2.
Academic Article The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2.
Academic Article Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination.
Academic Article Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2.
Academic Article Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination.
Academic Article Mechanism and regulation of class switch recombination.
Academic Article p53 represses class switch recombination to IgG2a through its antioxidant function.
Concept Immunoglobulin Variable Region
Concept Somatic Hypermutation, Immunoglobulin
Concept Immunoglobulin alpha-Chains
Concept Genes, Immunoglobulin
Concept Immunoglobulin G
Concept Immunoglobulin A
Concept Immunoglobulin Switch Region
Concept Immunoglobulin Heavy Chains
Concept Immunoglobulin Isotypes
Concept Immunoglobulin Constant Regions
Concept Immunoglobulin Class Switching
Concept Immunoglobulin mu-Chains
Academic Article DNA polymerases ? and ? do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations.
Academic Article Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation.
Academic Article Apurinic/apyrimidinic endonuclease 2 regulates the expansion of germinal centers by protecting against activation-induced cytidine deaminase-independent DNA damage in B cells.
Academic Article IgH chain class switch recombination: mechanism and regulation.
Academic Article Response to comment on "IgH chain class switch recombination: mechanism and regulation".
Academic Article Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination.
Academic Article APE2 Promotes AID-Dependent Somatic Hypermutation in Primary B Cell Cultures That Is Suppressed by APE1.
Search Criteria
  • Immunoglobulin Variable Region