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Rock, Kenneth

One or more keywords matched the following items that are connected to Rock, Kenneth

Item Type	Name
Academic Article	Proteasome subunits X and Y alter peptidase activities in opposite ways to the interferon-gamma-induced subunits LMP2 and LMP7.
Academic Article	Sequences that flank subdominant and cryptic epitopes influence the proteolytic generation of MHC class I-presented peptides.
Academic Article	Functions of the proteasome in antigen presentation.
Academic Article	Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules.
Academic Article	Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation.
Academic Article	Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide.
Academic Article	The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides.
Academic Article	Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase.
Academic Article	The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation.
Academic Article	Degradation of cell proteins and the generation of MHC class I-presented peptides.
Academic Article	Distinct proteolytic processes generate the C and N termini of MHC class I-binding peptides.
Academic Article	Proteolysis and class I major histocompatibility complex antigen presentation.
Academic Article	Not just research tools--proteasome inhibitors offer therapeutic promise.
Academic Article	Protein degradation and the generation of MHC class I-presented peptides.
Academic Article	Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7.
Academic Article	Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes.
Academic Article	Post-proteasomal antigen processing for major histocompatibility complex class I presentation.
Academic Article	Analysis of the role of bleomycin hydrolase in antigen presentation and the generation of CD8 T cell responses.
Academic Article	Altered peptidase and viral-specific T cell response in LMP2 mutant mice.
Academic Article	Role of proteasomes in antigen presentation.
Academic Article	Gamma-interferon causes a selective induction of the lysosomal proteases, cathepsins B and L, in macrophages.
Academic Article	A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules.
Academic Article	Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules.
Concept	Cysteine Endopeptidases
Concept	Cysteine Proteinase Inhibitors
Academic Article	Specialized proteasome subunits have an essential role in the thymic selection of CD8(+) T cells.

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