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Khvorova, Anastasia
One or more keywords matched the following items that are connected to Khvorova, Anastasia
Item TypeName
Academic Article Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing.
Academic Article Synthesis and Evaluation of Parenchymal Retention and Efficacy of a Metabolically Stable O-Phosphocholine-N-docosahexaenoyl-l-serine siRNA Conjugate in Mouse Brain.
Academic Article Optimized Cholesterol-siRNA Chemistry Improves Productive Loading onto Extracellular Vesicles.
Academic Article Transvascular Delivery of Hydrophobically Modified siRNAs: Gene Silencing in the Rat Brain upon Disruption of the Blood-Brain Barrier.
Academic Article Rac1 Activity Is Modulated by Huntingtin and Dysregulated in Models of Huntington's Disease.
Academic Article A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system.
Academic Article Loss of huntingtin function slows synaptic vesicle endocytosis in striatal neurons from the httQ140/Q140 mouse model of Huntington's disease.
Academic Article Enriched chitosan nanoparticles loaded with siRNA are effective in lowering Huntington's disease gene expression following intranasal administration.
Concept Huntingtin Protein
Academic Article Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington's disease models.
Academic Article Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.
Academic Article More than 185 CAG repeats: a point of no return in Huntington's disease biology.
Academic Article A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system.
Academic Article mRNA Nuclear Clustering Leads to a Difference in Mutant Huntingtin mRNA and Protein Silencing by siRNAs In Vivo.
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  • Huntingtin Protein