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One or more keywords matched the following items that are connected to Khvorova, Anastasia
Item TypeName
Concept Huntington Disease
Academic Article Nuclear Localization of Huntingtin mRNA Is Specific to Cells of Neuronal Origin.
Academic Article Rac1 Activity Is Modulated by Huntingtin and Dysregulated in Models of Huntington's Disease.
Academic Article Loss of huntingtin function slows synaptic vesicle endocytosis in striatal neurons from the httQ140/Q140 mouse model of Huntington's disease.
Academic Article Enriched chitosan nanoparticles loaded with siRNA are effective in lowering Huntington's disease gene expression following intranasal administration.
Academic Article Structurally constrained phosphonate internucleotide linkage impacts oligonucleotide-enzyme interaction, and modulates siRNA activity and allele specificity.
Academic Article Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington's disease models.
Academic Article Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.
Academic Article Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.
Academic Article More than 185 CAG repeats: a point of no return in Huntington's disease biology.
Academic Article A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system.
Academic Article mRNA Nuclear Clustering Leads to a Difference in Mutant Huntingtin mRNA and Protein Silencing by siRNAs In Vivo.
Academic Article Suppression of Huntington's Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding.
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  • Huntington Disease