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Khvorova, Anastasia
One or more keywords matched the following items that are connected to
Khvorova, Anastasia
Item Type
Name
Concept
Huntington Disease
Academic Article
Nuclear Localization of Huntingtin mRNA Is Specific to Cells of Neuronal Origin.
Academic Article
Rac1 Activity Is Modulated by Huntingtin and Dysregulated in Models of Huntington's Disease.
Academic Article
Loss of huntingtin function slows synaptic vesicle endocytosis in striatal neurons from the httQ140/Q140 mouse model of Huntington's disease.
Academic Article
Enriched chitosan nanoparticles loaded with siRNA are effective in lowering Huntington's disease gene expression following intranasal administration.
Academic Article
Structurally constrained phosphonate internucleotide linkage impacts oligonucleotide-enzyme interaction, and modulates siRNA activity and allele specificity.
Academic Article
Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington's disease models.
Academic Article
Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.
Academic Article
Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.
Academic Article
More than 185 CAG repeats: a point of no return in Huntington's disease biology.
Academic Article
A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system.
Academic Article
mRNA Nuclear Clustering Leads to a Difference in Mutant Huntingtin mRNA and Protein Silencing by siRNAs In Vivo.
Academic Article
Suppression of Huntington's Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding.
Search Criteria
Huntington Disease