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Heneka, Michael

One or more keywords matched the following items that are connected to Heneka, Michael

Item Type	Name
Academic Article	PPARgamma as a therapeutic target in central nervous system diseases.
Academic Article	Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease.
Academic Article	Long-term cognitive impairment, neuronal loss and reduced cortical cholinergic innervation after recovery from sepsis in a rodent model.
Academic Article	Microglial activation in a neuroinflammational animal model of schizophrenia--a pilot study.
Academic Article	Nitration of tyrosine 10 critically enhances amyloid ? aggregation and plaque formation.
Academic Article	Nitric oxide decreases the enzymatic activity of insulin degrading enzyme in APP/PS1 mice.
Academic Article	PPAR?/RXRa-induced and CD36-mediated microglial amyloid-? phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice.
Academic Article	Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation.
Academic Article	Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice.
Academic Article	Systemic inflammation induces apoptosis with variable vulnerability of different brain regions.
Academic Article	PPARgamma and RXRgamma ligands act synergistically as potent antineoplastic agents in vitro and in vivo glioma models.
Academic Article	Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.
Academic Article	Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson's disease.
Academic Article	Extracellular phosphorylation of the amyloid ?-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease.
Academic Article	Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.
Academic Article	Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease.
Academic Article	Mrp14 deficiency ameliorates amyloid ? burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing.
Concept	Disease Models, Animal
Academic Article	Neuroinflammation in Alzheimer's disease.
Academic Article	?-Secretase processing of APP inhibits neuronal activity in the hippocampus.
Academic Article	Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer's Disease.
Academic Article	Inflammasome activation and innate immunity in Alzheimer's disease.
Academic Article	IL-17A Promotes Granulocyte Infiltration, Myelin Loss, Microglia Activation, and Behavioral Deficits During Cuprizone-Induced Demyelination.
Academic Article	Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-? plaques: A potential role in shaping plaque pathology?
Academic Article	CNS-Specific Synthesis of Interleukin 23 Induces a Progressive Cerebellar Ataxia and the Accumulation of Both T and B Cells in the Brain: Characterization of a Novel Transgenic Mouse Model.
Academic Article	Systemic inflammation impairs microglial A? clearance through NLRP3 inflammasome.
Academic Article	Quantitative proteomics of synaptosome S-nitrosylation in Alzheimer's disease.
Academic Article	Vaccination with (1-11)E2 in alum efficiently induces an antibody response to ?-amyloid without affecting brain ?-amyloid load and microglia activation in 3xTg mice.
Academic Article	Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease.
Academic Article	Deletion of the inflammatory S100-A9/MRP14 protein does not influence survival in hSOD1G93A ALS mice.
Academic Article	Differential interaction with TREM2 modulates microglial uptake of modified A? species.
Academic Article	Proteopathic tau primes and activates interleukin-1? via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway.
Academic Article	Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology.
Academic Article	Reactive microglia are the major source of tumor necrosis factor alpha and contribute to astrocyte dysfunction and acute seizures in experimental temporal lobe epilepsy.

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Disease Models Animal