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Search Results to Michael Thomas Heneka MD

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One or more keywords matched the following items that are connected to Heneka, Michael

Item TypeName
Academic Article Intrinsic regulation of brain inflammatory responses.
Academic Article Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide.
Academic Article PPARgamma as a therapeutic target in central nervous system diseases.
Academic Article Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease.
Academic Article Inflammatory processes in Alzheimer's disease.
Academic Article Long-term cognitive impairment, neuronal loss and reduced cortical cholinergic innervation after recovery from sepsis in a rodent model.
Academic Article PPARs in the brain.
Academic Article The role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in Alzheimer's disease: therapeutic implications.
Academic Article Neuroglia in neurodegeneration.
Academic Article Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease.
Academic Article Neuroinflammatory processes in Alzheimer's disease.
Academic Article Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion.
Academic Article Restraint stress increases neuroinflammation independently of amyloid ß levels in amyloid precursor protein/PS1 transgenic mice.
Academic Article Microglial activation in a neuroinflammational animal model of schizophrenia--a pilot study.
Academic Article The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers.
Academic Article Nitration of tyrosine 10 critically enhances amyloid ß aggregation and plaque formation.
Academic Article Opposing roles for CXCR3 signaling in central nervous system versus ocular inflammation mediated by the astrocyte-targeted production of IL-12.
Academic Article TLR2 is a primary receptor for Alzheimer's amyloid ß peptide to trigger neuroinflammatory activation.
Academic Article Nitric oxide decreases the enzymatic activity of insulin degrading enzyme in APP/PS1 mice.
Academic Article PPAR?/RXRa-induced and CD36-mediated microglial amyloid-ß phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice.
Academic Article NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Academic Article The AD-CSF-index discriminates Alzheimer's disease patients from healthy controls: a validation study.
Academic Article Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons.
Academic Article Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation.
Academic Article Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice.
Academic Article Systemic inflammation induces apoptosis with variable vulnerability of different brain regions.
Academic Article Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma.
Academic Article Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice.
Academic Article Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms.
Academic Article Disease-modifying therapies in Alzheimer's disease: how far have we come?
Academic Article Drug insight: effects mediated by peroxisome proliferator-activated receptor-gamma in CNS disorders.
Academic Article PPARgamma agonists as therapeutics for the treatment of Alzheimer's disease.
Academic Article PPARs in Alzheimer's Disease.
Academic Article PPARgamma and RXRgamma ligands act synergistically as potent antineoplastic agents in vitro and in vivo glioma models.
Academic Article Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.
Academic Article Locus coeruleus degeneration exacerbates olfactory deficits in APP/PS1 transgenic mice.
Academic Article Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson's disease.
Academic Article Extracellular phosphorylation of the amyloid ß-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease.
Academic Article Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.
Academic Article Glial cells in (patho)physiology.
Academic Article Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease.
Academic Article Impact and Therapeutic Potential of PPARs in Alzheimer's Disease.
Academic Article A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis.
Academic Article Long-term neuromuscular sequelae of critical illness.
Academic Article A pan-European study of the C9orf72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats.
Academic Article Mrp14 deficiency ameliorates amyloid ß burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing.
Academic Article Clinical symptoms and risk factors in cerebral microangiopathy patients.
Concept Disease Models, Animal
Concept Central Nervous System Diseases
Concept Mitochondrial Diseases
Concept Eye Diseases
Concept Brain Diseases
Concept Communicable Diseases
Concept Disease Progression
Concept Neurodegenerative Diseases
Concept Chronic Disease
Concept Disease-Free Survival
Concept Acute Disease
Concept Genetic Predisposition to Disease
Concept Nervous System Diseases
Concept Demyelinating Diseases
Concept Alzheimer Disease
Concept Neuromuscular Diseases
Concept Parkinson Disease
Academic Article ADO: a disease ontology representing the domain knowledge specific to Alzheimer's disease.
Academic Article Long-term cerebral consequences of sepsis.
Academic Article Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease.
Academic Article Innate immune activation in neurodegenerative disease.
Academic Article TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.
Academic Article CXCR3 modulates glial accumulation and activation in cuprizone-induced demyelination of the central nervous system.
Academic Article Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia.
Academic Article Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration.
Academic Article Body fluid cytokine levels in mild cognitive impairment and Alzheimer's disease: a comparative overview.
Academic Article SUCLG2 identified as both a determinator of CSF Aß1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.
Academic Article Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes.
Academic Article Sepsis-associated encephalopathy versus sepsis-induced encephalopathy--authors' reply.
Academic Article CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model.
Academic Article PLD3 in non-familial Alzheimer's disease.
Academic Article Innate immunity in Alzheimer's disease.
Academic Article Neuroinflammation in Alzheimer's disease.
Academic Article Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson's Disease.
Academic Article A distinct clinical phenotype in a German kindred with motor neuron disease carrying a CHCHD10 mutation.
Academic Article ?-Secretase processing of APP inhibits neuronal activity in the hippocampus.
Academic Article Microglia in Alzheimer's disease: the good, the bad and the ugly.
Academic Article sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers.
Academic Article Thoughts on Obesity and Brain Glucose.
Academic Article Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer's Disease.
Academic Article Inflammasome activation and innate immunity in Alzheimer's disease.
Academic Article Danger-associated molecular patterns in Alzheimer's disease.
Academic Article Microglia-derived ASC specks cross-seed amyloid-ß in Alzheimer's disease.
Academic Article Multicenter Resting State Functional Connectivity in Prodromal and Dementia Stages of Alzheimer's Disease.
Academic Article Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer's Disease.
Academic Article Screening for Niemann-Pick Type C Disease in a Memory Clinic Cohort.
Academic Article A guiding map for inflammation.
Academic Article Inflammasome signalling in brain function and neurodegenerative disease.
Academic Article Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease.
Academic Article Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer's disease.
Academic Article The ERICA Score: An MR Imaging-based Visual Scoring System for the Assessment of Entorhinal Cortex Atrophy in Alzheimer Disease.
Academic Article Targeting Neuroinflammation to Treat Alzheimer's Disease.
Academic Article Microglia modulation through external vagus nerve stimulation in a murine model of Alzheimer's disease.
Academic Article Neuroinflammatory responses in Alzheimer's disease.
Academic Article Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE).
Academic Article Smaller medial temporal lobe volumes in individuals with subjective cognitive decline and biomarker evidence of Alzheimer's disease-Data from three memory clinic studies.
Academic Article Microglia in Alzheimer's disease.
Academic Article Microglia take centre stage in neurodegenerative disease.
Academic Article Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples.
Academic Article Author Correction: Inflammasome signalling in brain function and neurodegenerative disease.
Academic Article Dysregulation of TLR5 and TAM Ligands in the Alzheimer's Brain as Contributors to Disease Progression.
Academic Article The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.
Academic Article Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis.
Academic Article [Neuroinflammation as motor of Alzheimer's disease].
Academic Article Quantitative proteomics of synaptosome S-nitrosylation in Alzheimer's disease.
Academic Article Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer's Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness.
Academic Article The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease.
Academic Article Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study.
Academic Article Inflammasome-mediated innate immunity in Alzheimer's disease.
Academic Article An immune-cell signature marks the brain in Alzheimer's disease.
Academic Article Microglia in Alzheimer's disease: Local heroes!
Academic Article Do infections have a role in the pathogenesis of Alzheimer disease?
Academic Article Neuroimmune Connections in Aging and Neurodegenerative Diseases.
Academic Article PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment.
Academic Article T cells in Alzheimer's disease: space invaders.
Academic Article Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease.
Academic Article Immediate and long-term consequences of COVID-19 infections for the development of neurological disease.
Academic Article Small vessel disease more than Alzheimer's disease determines diffusion MRI alterations in memory clinic patients.
Academic Article Interrelations of Alzheimer´s disease candidate biomarkers neurogranin, fatty acid-binding protein 3 and ferritin to neurodegeneration and neuroinflammation.
Academic Article Multimodal MRI analysis of basal forebrain structure and function across the Alzheimer's disease spectrum.

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