| Item Type | Name |
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Academic Article
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Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide.
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Academic Article
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The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice.
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Academic Article
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Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease.
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Academic Article
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Reduction of amyloid angiopathy and Abeta plaque burden after enriched housing in TgCRND8 mice: involvement of multiple pathways.
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Academic Article
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Inhibition of in vivo glioma growth and invasion by peroxisome proliferator-activated receptor gamma agonist treatment.
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Academic Article
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Switching on the lights for gene therapy.
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Academic Article
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Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
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Academic Article
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NOS2 gene deficiency protects from sepsis-induced long-term cognitive deficits.
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Academic Article
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Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion.
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Academic Article
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Restraint stress increases neuroinflammation independently of amyloid ? levels in amyloid precursor protein/PS1 transgenic mice.
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Academic Article
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Microglial activation in a neuroinflammational animal model of schizophrenia--a pilot study.
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Academic Article
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Nitration of tyrosine 10 critically enhances amyloid ? aggregation and plaque formation.
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Academic Article
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Opposing roles for CXCR3 signaling in central nervous system versus ocular inflammation mediated by the astrocyte-targeted production of IL-12.
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Academic Article
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TLR2 is a primary receptor for Alzheimer's amyloid ? peptide to trigger neuroinflammatory activation.
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Academic Article
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Nitric oxide decreases the enzymatic activity of insulin degrading enzyme in APP/PS1 mice.
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Academic Article
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Selective loss of noradrenaline exacerbates early cognitive dysfunction and synaptic deficits in APP/PS1 mice.
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Academic Article
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Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis.
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Academic Article
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PPAR?/RXRa-induced and CD36-mediated microglial amyloid-? phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice.
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Academic Article
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NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
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Academic Article
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Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons.
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Academic Article
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Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase.
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Academic Article
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Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation.
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Academic Article
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Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice.
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Academic Article
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Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice.
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Academic Article
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Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma.
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Academic Article
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Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice.
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Academic Article
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Imaging-guided gene therapy of experimental gliomas.
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Academic Article
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Multitracer positron emission tomographic imaging of exogenous gene expression mediated by a universal herpes simplex virus 1 amplicon vector.
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Academic Article
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Noradrenergic denervation facilitates the release of acetylcholine and serotonin in the hippocampus: towards a mechanism underlying upregulations described in MCI patients.
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Academic Article
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PPARgamma and RXRgamma ligands act synergistically as potent antineoplastic agents in vitro and in vivo glioma models.
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Academic Article
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Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits.
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Academic Article
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Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.
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Academic Article
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Distinct modulation of microglial amyloid ? phagocytosis and migration by neuropeptides (i).
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Academic Article
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Locus coeruleus degeneration exacerbates olfactory deficits in APP/PS1 transgenic mice.
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Academic Article
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Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson's disease.
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Academic Article
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Extracellular phosphorylation of the amyloid ?-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease.
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Academic Article
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Critical role of astroglial apolipoprotein E and liver X receptor-a expression for microglial A? phagocytosis.
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Academic Article
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Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.
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Academic Article
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Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease.
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Academic Article
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A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis.
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Academic Article
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Mrp14 deficiency ameliorates amyloid ? burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing.
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Academic Article
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CNS-targeted production of IL-17A induces glial activation, microvascular pathology and enhances the neuroinflammatory response to systemic endotoxemia.
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Academic Article
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Studying M1 and M2 states in adult microglia.
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Concept
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Mice, Inbred BALB C
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Concept
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Mice, Knockout
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Concept
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Mice, Inbred C3H
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Concept
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Mice
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Concept
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Mice, Inbred C57BL
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Concept
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Mice, Transgenic
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Concept
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Mice, Nude
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Academic Article
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Ear2 deletion causes early memory and learning deficits in APP/PS1 mice.
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Academic Article
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CXCR3 modulates glial accumulation and activation in cuprizone-induced demyelination of the central nervous system.
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Academic Article
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CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model.
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Academic Article
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Pan-PPAR modulation effectively protects APP/PS1 mice from amyloid deposition and cognitive deficits.
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Academic Article
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Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson's Disease.
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Academic Article
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?-Secretase processing of APP inhibits neuronal activity in the hippocampus.
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Academic Article
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Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
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Academic Article
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Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer's Disease.
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Academic Article
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Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised.
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Academic Article
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Inflammasome activation and innate immunity in Alzheimer's disease.
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Academic Article
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IL-17A Promotes Granulocyte Infiltration, Myelin Loss, Microglia Activation, and Behavioral Deficits During Cuprizone-Induced Demyelination.
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Academic Article
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Intramembranous processing by ?-secretase regulates reverse signaling of ephrin-B2 in migration of microglia.
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Academic Article
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Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice.
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Academic Article
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Activation of the NLRP3 inflammasome in microglia: the role of ceramide.
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Academic Article
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United Again: STING and the Police.
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Academic Article
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Microglia-derived ASC specks cross-seed amyloid-? in Alzheimer's disease.
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Academic Article
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Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer's Disease.
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Academic Article
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Proteome profiling of s-nitrosylated synaptosomal proteins by isobaric mass tags.
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Academic Article
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Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-? plaques: A potential role in shaping plaque pathology?
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Academic Article
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Variability and temporal dynamics of novel object recognition in aging male C57BL/6 mice.
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Academic Article
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The NMDA receptor antagonist Radiprodil reverses the synaptotoxic effects of different amyloid-beta (A?) species on long-term potentiation (LTP).
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Academic Article
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Microglia in Alzheimer's disease.
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Academic Article
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CNS-Specific Synthesis of Interleukin 23 Induces a Progressive Cerebellar Ataxia and the Accumulation of Both T and B Cells in the Brain: Characterization of a Novel Transgenic Mouse Model.
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Academic Article
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Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis.
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Academic Article
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Systemic inflammation impairs microglial A? clearance through NLRP3 inflammasome.
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Academic Article
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In Vivo Phagocytosis Analysis of Amyloid Beta.
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Academic Article
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Quantitative proteomics of synaptosome S-nitrosylation in Alzheimer's disease.
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Academic Article
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The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease.
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Academic Article
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Norepinephrine as a modulator of microglial dynamics.
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Academic Article
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NLRP3 inflammasome activation drives tau pathology.
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Academic Article
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Vaccination with (1-11)E2 in alum efficiently induces an antibody response to ?-amyloid without affecting brain ?-amyloid load and microglia activation in 3xTg mice.
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Academic Article
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Soluble A? oligomers and protofibrils induce NLRP3 inflammasome activation in microglia.
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Academic Article
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?-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia.
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Academic Article
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Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease.
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Academic Article
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Enduring Changes in Neuronal Function upon Systemic Inflammation Are NLRP3 Inflammasome Dependent.
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Academic Article
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mTOR-dependent translation amplifies microglia priming in aging mice.
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Academic Article
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Novel Phosphorylation-State Specific Antibodies Reveal Differential Deposition of Ser26 Phosphorylated A? Species in a Mouse Model of Alzheimer's Disease.
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Academic Article
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Deletion of the inflammatory S100-A9/MRP14 protein does not influence survival in hSOD1G93A ALS mice.
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Academic Article
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Astrocyte-specific expression of interleukin 23 leads to an aggravated phenotype and enhanced inflammatory response with B cell accumulation in the EAE model.
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Academic Article
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In vivo mechanisms of cortical network dysfunction induced by systemic inflammation.
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Academic Article
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Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing.
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Academic Article
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Differential interaction with TREM2 modulates microglial uptake of modified A? species.
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Academic Article
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Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct a-Synuclein Assemblies.
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Academic Article
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Proteopathic tau primes and activates interleukin-1? via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway.
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Academic Article
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Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.
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Academic Article
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SFRP1 modulates astrocyte-to-microglia crosstalk in acute and chronic neuroinflammation.
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Academic Article
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mTOR-dependent translation amplifies microglia priming in aging mice.
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Academic Article
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TREM2 modulates differential deposition of modified and non-modified A? species in extracellular plaques and intraneuronal deposits.
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Academic Article
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Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology.
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Academic Article
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Inflammasome activation in neurodegenerative diseases.
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Academic Article
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Reactive microglia are the major source of tumor necrosis factor alpha and contribute to astrocyte dysfunction and acute seizures in experimental temporal lobe epilepsy.
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Academic Article
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ApoE4 makes microglia trem2bling.
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Academic Article
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NLRP3-directed antisense oligonucleotides reduce microglial immunoactivities in vitro.
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Academic Article
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ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain.
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Academic Article
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Characterizing microglial senescence: Tau as a key player.
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Academic Article
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Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease.
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Academic Article
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The endotoxin hypothesis of Alzheimer's disease.
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Academic Article
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TREM1 is the new kid on the block for the aging-associated innate immune response and Alzheimer's disease.
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Academic Article
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Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes.
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