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Heneka, Michael

One or more keywords matched the following items that are connected to Heneka, Michael

Item Type	Name
Academic Article	The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice.
Academic Article	Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease.
Academic Article	Reduction of amyloid angiopathy and Abeta plaque burden after enriched housing in TgCRND8 mice: involvement of multiple pathways.
Academic Article	Restraint stress increases neuroinflammation independently of amyloid ? levels in amyloid precursor protein/PS1 transgenic mice.
Academic Article	Nitration of tyrosine 10 critically enhances amyloid ? aggregation and plaque formation.
Academic Article	TLR2 is a primary receptor for Alzheimer's amyloid ? peptide to trigger neuroinflammatory activation.
Academic Article	Nitric oxide decreases the enzymatic activity of insulin degrading enzyme in APP/PS1 mice.
Academic Article	NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Academic Article	Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice.
Academic Article	Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice.
Academic Article	Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice.
Academic Article	Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits.
Academic Article	Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.
Academic Article	Locus coeruleus degeneration exacerbates olfactory deficits in APP/PS1 transgenic mice.
Academic Article	Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson's disease.
Academic Article	Extracellular phosphorylation of the amyloid ?-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease.
Academic Article	Critical role of astroglial apolipoprotein E and liver X receptor-a expression for microglial A? phagocytosis.
Academic Article	Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.
Academic Article	Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease.
Academic Article	Mrp14 deficiency ameliorates amyloid ? burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing.
Academic Article	CNS-targeted production of IL-17A induces glial activation, microvascular pathology and enhances the neuroinflammatory response to systemic endotoxemia.
Academic Article	Studying M1 and M2 states in adult microglia.
Concept	Mice, Transgenic
Academic Article	Ear2 deletion causes early memory and learning deficits in APP/PS1 mice.
Academic Article	CXCR3 modulates glial accumulation and activation in cuprizone-induced demyelination of the central nervous system.
Academic Article	Pan-PPAR modulation effectively protects APP/PS1 mice from amyloid deposition and cognitive deficits.
Academic Article	Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson's Disease.
Academic Article	Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer's Disease.
Academic Article	IL-17A Promotes Granulocyte Infiltration, Myelin Loss, Microglia Activation, and Behavioral Deficits During Cuprizone-Induced Demyelination.
Academic Article	Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-? plaques: A potential role in shaping plaque pathology?
Academic Article	CNS-Specific Synthesis of Interleukin 23 Induces a Progressive Cerebellar Ataxia and the Accumulation of Both T and B Cells in the Brain: Characterization of a Novel Transgenic Mouse Model.
Academic Article	Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis.
Academic Article	Quantitative proteomics of synaptosome S-nitrosylation in Alzheimer's disease.
Academic Article	Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease.
Academic Article	mTOR-dependent translation amplifies microglia priming in aging mice.
Academic Article	Astrocyte-specific expression of interleukin 23 leads to an aggravated phenotype and enhanced inflammatory response with B cell accumulation in the EAE model.
Academic Article	Differential interaction with TREM2 modulates microglial uptake of modified A? species.
Academic Article	Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology.
Academic Article	ApoE4 makes microglia trem2bling.
Academic Article	Characterizing microglial senescence: Tau as a key player.
Academic Article	Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease.

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Mice Transgenic