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The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice.
A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration.
A distinct clinical phenotype in a German kindred with motor neuron disease carrying a CHCHD10 mutation.
TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.
Innate Immunity and Neurodegeneration.
Safety and efficacy of rasagiline as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomised, double-blind, parallel-group, placebo-controlled, phase 2 trial.
A novel CHCHD10 mutation implicates a Mia40-dependent mitochondrial import deficit in ALS.
Deletion of the inflammatory S100-A9/MRP14 protein does not influence survival in hSOD1G93A ALS mice.
Teaching an old dog new tricks: serum troponin T as a biomarker in amyotrophic lateral sclerosis.
CNS Superficial Siderosis Mimicking a Motor Neuron Disease.
Motor Neuron Disease