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Heneka, Michael

One or more keywords matched the following items that are connected to Heneka, Michael

Item Type	Name
Academic Article	Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide.
Academic Article	Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease.
Academic Article	Reduction of amyloid angiopathy and Abeta plaque burden after enriched housing in TgCRND8 mice: involvement of multiple pathways.
Academic Article	Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
Academic Article	Neuroinflammatory processes in Alzheimer's disease.
Academic Article	Restraint stress increases neuroinflammation independently of amyloid ? levels in amyloid precursor protein/PS1 transgenic mice.
Academic Article	Nitration of tyrosine 10 critically enhances amyloid ? aggregation and plaque formation.
Academic Article	Selective loss of noradrenaline exacerbates early cognitive dysfunction and synaptic deficits in APP/PS1 mice.
Academic Article	PPAR?/RXRa-induced and CD36-mediated microglial amyloid-? phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice.
Academic Article	Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase.
Academic Article	Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice.
Academic Article	Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma.
Academic Article	Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice.
Academic Article	Disease-modifying therapies in Alzheimer's disease: how far have we come?
Academic Article	alpha-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Abeta generation.
Academic Article	Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits.
Academic Article	Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.
Academic Article	Critical role of astroglial apolipoprotein E and liver X receptor-a expression for microglial A? phagocytosis.
Academic Article	Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.
Academic Article	Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease.
Academic Article	Mrp14 deficiency ameliorates amyloid ? burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing.
Concept	Amyloid beta-Protein Precursor
Concept	Amyloid Precursor Protein Secretases
Academic Article	Ear2 deletion causes early memory and learning deficits in APP/PS1 mice.
Academic Article	Pan-PPAR modulation effectively protects APP/PS1 mice from amyloid deposition and cognitive deficits.
Academic Article	?-Secretase processing of APP inhibits neuronal activity in the hippocampus.
Academic Article	Intramembranous processing by ?-secretase regulates reverse signaling of ephrin-B2 in migration of microglia.
Academic Article	Microglia-derived ASC specks cross-seed amyloid-? in Alzheimer's disease.
Academic Article	Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease.
Academic Article	Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis.
Academic Article	Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
Academic Article	Differential interaction with TREM2 modulates microglial uptake of modified A? species.
Academic Article	Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology.
Academic Article	Association of Neurogranin and BACE1 With Clinical Cognitive Decline in Individuals With Subjective Cognitive Decline.
Academic Article	Proliferating Microglia Exhibit Unique Transcriptional and Functional Alterations in Alzheimer's Disease.

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Serum Amyloid A Protein