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One or more keywords matched the following items that are connected to Golenbock, Douglas
Item TypeName
Academic Article Engagement of the Lewis X antigen (CD15) results in monocyte activation.
Academic Article Effects of interleukin-10 on human peripheral blood mononuclear cell responses to Cryptococcus neoformans, Candida albicans, and lipopolysaccharide.
Academic Article Targeted deletion of the lipopolysaccharide (LPS)-binding protein gene leads to profound suppression of LPS responses ex vivo, whereas in vivo responses remain intact.
Academic Article Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers.
Academic Article Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses.
Academic Article Membrane-associated proteins of a lipopolysaccharide-deficient mutant of Neisseria meningitidis activate the inflammatory response through toll-like receptor 2.
Academic Article Characterization of proinflammatory cytokine production and CD14 expression by murine alveolar macrophage cell lines.
Academic Article Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent.
Academic Article Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-kappaB activation and TNF production induced by lipopolysaccharide and group B streptococcal cell walls.
Academic Article Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus.
Academic Article Construction of a lipopolysaccharide reporter cell line and its use in identifying mutants defective in endotoxin, but not TNF-alpha, signal transduction.
Academic Article Lipopolysaccharide-induced stimulation of CD11b/CD18 expression on neutrophils. Evidence of specific receptor-based response and inhibition by lipid A-based antagonists.
Academic Article Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
Academic Article Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice.
Academic Article Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells.
Academic Article IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
Academic Article Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi.
Academic Article Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation.
Academic Article The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
Academic Article MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection.
Academic Article Human cardiac inflammatory responses triggered by Coxsackie B viruses are mainly Toll-like receptor (TLR) 8-dependent.
Academic Article Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes.
Academic Article Comparative toll-like receptor 4-mediated innate host defense to Bordetella infection.
Academic Article MyD88-dependent pathways mediate resistance to Cryptosporidium parvum infection in mice.
Academic Article c-Jun kinase is a critical signaling molecule in a neonatal model of group B streptococcal sepsis.
Academic Article The biology of Toll-like receptors.
Academic Article A mechanism for neurodegeneration induced by group B streptococci through activation of the TLR2/MyD88 pathway in microglia.
Academic Article Toll-like receptor 4 mediates intracellular signaling without TNF-alpha release in response to Cryptococcus neoformans polysaccharide capsule.
Academic Article Toll-like receptor-dependent discrimination of streptococci.
Academic Article A bacterial carbohydrate links innate and adaptive responses through Toll-like receptor 2.
Academic Article Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.
Academic Article Identification of a key pathway required for the sterile inflammatory response triggered by dying cells.
Academic Article YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction.
Academic Article Activation of TLR2 and TLR4 by glycosylphosphatidylinositols derived from Toxoplasma gondii.
Academic Article Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling.
Academic Article Lipoteichoic acid-induced lung inflammation depends on TLR2 and the concerted action of TLR4 and the platelet-activating factor receptor.
Academic Article Comparative study of lipopolysaccharide-, lipid IVa-, and lipid X-induced tumor necrosis factor production in murine macrophage-like cell lines.
Academic Article Lipopolysaccharide, but not lethal infection, releases tumor necrosis factor in mice.
Academic Article TIRAP: how Toll receptors fraternize.
Academic Article TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA.
Academic Article Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function.
Academic Article Role of p38 and early growth response factor 1 in the macrophage response to group B streptococcus.
Academic Article Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide.
Academic Article A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.
Academic Article Mal connects TLR2 to PI3Kinase activation and phagocyte polarization.
Academic Article Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.
Academic Article Natural loss-of-function mutation of myeloid differentiation protein 88 disrupts its ability to form Myddosomes.
Academic Article Activation of the NLRP3 inflammasome by group B streptococci.
Academic Article Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production.
Academic Article DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation.
Academic Article Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation.
Academic Article Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers.
Academic Article Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways.
Academic Article The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism.
Academic Article Heat-killed Brucella abortus induces TNF and IL-12p40 by distinct MyD88-dependent pathways: TNF, unlike IL-12p40 secretion, is Toll-like receptor 2 dependent.
Academic Article LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
Academic Article IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts.
Academic Article TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Academic Article CD14-mediated translocation of nuclear factor-kappa B induced by lipopolysaccharide does not require tyrosine kinase activity.
Academic Article Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity.
Academic Article Acyclic analogue of lipid A stimulates TNF-alpha and arachidonate release via a unique LPS-signaling pathway.
Academic Article The inflammatory cytokine response to Chlamydia trachomatis infection is endotoxin mediated.
Academic Article Neither CD14 nor serum is absolutely necessary for activation of mononuclear phagocytes by bacterial lipopolysaccharide.
Academic Article Production of tumor necrosis factor alpha in human leukocytes stimulated by Cryptococcus neoformans.
Academic Article Dual role of TLR2 and myeloid differentiation factor 88 in a mouse model of invasive group B streptococcal disease.
Academic Article Innate immune responses to Rhodococcus equi.
Academic Article The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades.
Academic Article Lipid A-like molecules that antagonize the effects of endotoxins on human monocytes.
Academic Article Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection.
Academic Article HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.
Academic Article MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals.
Academic Article Combinatorial pattern recognition receptor signaling alters the balance of life and death in macrophages.
Academic Article NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.
Academic Article MyD88-dependent activation of dendritic cells and CD4(+) T lymphocytes mediates symptoms, but is not required for the immunological control of parasites during rodent malaria.
Academic Article Plasmodium falciparum infection causes proinflammatory priming of human TLR responses.
Academic Article MUC1 mucin is a negative regulator of toll-like receptor signaling.
Academic Article Lymphocytic choriomeningitis virus (LCMV) infection of CNS glial cells results in TLR2-MyD88/Mal-dependent inflammatory responses.
Academic Article TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway.
Academic Article MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.
Academic Article TLR3-mediated IFN-? gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like.
Academic Article Macrophages recognize streptococci through bacterial single-stranded RNA.
Academic Article MyD88-dependent pathway is essential for the innate immunity to Enterocytozoon bieneusi.
Academic Article Toll-like receptors participate in macrophage activation and intracellular control of Leishmania (Viannia) panamensis.
Academic Article Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi.
Academic Article Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome.
Academic Article NO is a macrophage autonomous modifier of the cytokine response to streptococcal single-stranded RNA.
Academic Article Interferon-? and granulocyte/monocyte colony-stimulating factor production by natural killer cells involves different signaling pathways and the adaptor stimulator of interferon genes (STING).
Academic Article The history of Toll-like receptors - redefining innate immunity.
Academic Article SDZ MRL 953, a lipid A analog as selective cytokine inducer.
Concept TNF Receptor-Associated Factor 6
Concept TNF Receptor-Associated Factor 3
Concept Myeloid Differentiation Factor 88
Concept Interferon Regulatory Factor-7
Concept STAT3 Transcription Factor
Concept Complement Factor H
Concept Tumor Necrosis Factor-alpha
Concept Granulocyte-Macrophage Colony-Stimulating Factor
Concept Interferon Regulatory Factor-3
Concept Transcription Factor AP-1
Concept Receptors, Tumor Necrosis Factor, Type I
Concept Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
Concept Growth Differentiation Factor 5
Concept Receptors, Tumor Necrosis Factor
Concept Platelet Activating Factor
Concept Transcription Factor RelA
Academic Article Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection.
Academic Article TRIF signaling is essential for TLR4-driven IgE class switching.
Academic Article A Novel Factor H-Fc Chimeric Immunotherapeutic Molecule against Neisseria gonorrhoeae.
Academic Article Cyclic GMP-AMP Synthase Is the Cytosolic Sensor of Plasmodium falciparum Genomic DNA and Activates Type I IFN in Malaria.
Academic Article Daily Rhythms of TNF? Expression and Food Intake Regulate Synchrony of Plasmodium Stages with the Host Circadian Cycle.
Academic Article The Single Nucleotide Polymorphism Mal-D96N Mice Provide New Insights into Functionality of Mal in TLR Immune Responses.
Academic Article The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2.
Academic Article Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR.
Academic Article Lymphocyte crosstalk is required for monocyte-intrinsic trained immunity to Plasmodium falciparum.
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