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Search Results to Douglas T Golenbock MD

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One or more keywords matched the following items that are connected to Golenbock, Douglas

Item TypeName
Academic Article Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses.
Academic Article Innate immune recognition of lipopolysaccharide by endothelial cells.
Academic Article Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
Academic Article Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.
Academic Article Proinflammatory phenotype of vascular smooth muscle cells: role of efficient Toll-like receptor 4 signaling.
Academic Article MD-2 expression is not required for cell surface targeting of Toll-like receptor 4 (TLR4).
Academic Article Immunology. The shape of things to come.
Academic Article Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling.
Academic Article Phagocytosis and intracellular killing of MD-2 opsonized gram-negative bacteria depend on TLR4 signaling.
Academic Article Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4.
Academic Article Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.
Academic Article MD-2 residues tyrosine 42, arginine 69, aspartic acid 122, and leucine 125 provide species specificity for lipid IVA.
Academic Article Endotoxin recognition and signal transduction by the TLR4/MD2-complex.
Academic Article Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105.
Academic Article Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.
Academic Article Inhibition of TLR-4/MD-2 signaling by RP105/MD-1.
Academic Article Trypsin-sensitive modulation of intestinal epithelial MD-2 as mechanism of lipopolysaccharide tolerance.
Academic Article Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on Toll-like receptor 4, CD44, and MD-2.
Academic Article IL-10 enhances MD-2 and CD14 expression in monocytes and the proteins are increased and correlated in HIV-infected patients.
Academic Article MD-2-mediated ionic interactions between lipid A and TLR4 are essential for receptor activation.
Academic Article Genome-wide expression profiling and mutagenesis studies reveal that lipopolysaccharide responsiveness appears to be absolutely dependent on TLR4 and MD-2 expression and is dependent upon intermolecular ionic interactions.
Concept Lymphocyte Antigen 96
Academic Article MD-2 is required for disulfide HMGB1-dependent TLR4 signaling.

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  • Lymphocyte Antigen 96