| Item Type | Name |
|
Academic Article
|
Targeted deletion of the lipopolysaccharide (LPS)-binding protein gene leads to profound suppression of LPS responses ex vivo, whereas in vivo responses remain intact.
|
|
Academic Article
|
CD11/CD18 and CD14 share a common lipid A signaling pathway.
|
|
Academic Article
|
Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction.
|
|
Academic Article
|
Lipopolysaccharide recognition, CD14, and lipopolysaccharide receptors.
|
|
Academic Article
|
Cutting edge: cells that carry A null allele for toll-like receptor 2 are capable of responding to endotoxin.
|
|
Academic Article
|
Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2.
|
|
Academic Article
|
Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis.
|
|
Academic Article
|
Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.
|
|
Academic Article
|
The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors.
|
|
Academic Article
|
A novel synthetic acyclic lipid A-like agonist activates cells via the lipopolysaccharide/toll-like receptor 4 signaling pathway.
|
|
Academic Article
|
Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers.
|
|
Academic Article
|
Structure and function of Toll-like receptor proteins.
|
|
Academic Article
|
Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses.
|
|
Academic Article
|
Membrane-associated proteins of a lipopolysaccharide-deficient mutant of Neisseria meningitidis activate the inflammatory response through toll-like receptor 2.
|
|
Academic Article
|
Toll-like receptor 2-dependent inhibition of macrophage class II MHC expression and antigen processing by 19-kDa lipoprotein of Mycobacterium tuberculosis.
|
|
Academic Article
|
Differential roles of TLR2 and TLR4 in the host response to Gram-negative bacteria: lessons from a lipopolysaccharide-deficient mutant of Neisseria meningitidis.
|
|
Academic Article
|
Lipopolysaccharides from periodontopathic bacteria Porphyromonas gingivalis and Capnocytophaga ochracea are antagonists for human toll-like receptor 4.
|
|
Academic Article
|
Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent.
|
|
Academic Article
|
Innate immune recognition of lipopolysaccharide by endothelial cells.
|
|
Academic Article
|
Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14.
|
|
Academic Article
|
Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4.
|
|
Academic Article
|
Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus.
|
|
Academic Article
|
LPS-binding proteins and receptors.
|
|
Academic Article
|
Construction of a lipopolysaccharide reporter cell line and its use in identifying mutants defective in endotoxin, but not TNF-alpha, signal transduction.
|
|
Academic Article
|
Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
|
|
Academic Article
|
Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice.
|
|
Academic Article
|
Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells.
|
|
Academic Article
|
Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection.
|
|
Academic Article
|
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
|
|
Academic Article
|
Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.
|
|
Academic Article
|
Adjuvants and their signaling pathways: beyond TLRs.
|
|
Academic Article
|
Biological activities of Bacteroides forsythus lipoproteins and their possible pathological roles in periodontal disease.
|
|
Academic Article
|
Relationship between structures and biological activities of mycoplasmal diacylated lipopeptides and their recognition by toll-like receptors 2 and 6.
|
|
Academic Article
|
Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response.
|
|
Academic Article
|
Non-mannose-capped lipoarabinomannan induces lung inflammation via toll-like receptor 2.
|
|
Academic Article
|
LPS-binding protein-deficient mice have an impaired defense against Gram-negative but not Gram-positive pneumonia.
|
|
Academic Article
|
Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi.
|
|
Academic Article
|
Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation.
|
|
Academic Article
|
Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.
|
|
Academic Article
|
The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
|
|
Academic Article
|
MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection.
|
|
Academic Article
|
Proinflammatory phenotype of vascular smooth muscle cells: role of efficient Toll-like receptor 4 signaling.
|
|
Academic Article
|
Lipopolysaccharide binding protein-deficient mice have a normal defense against pulmonary mycobacterial infection.
|
|
Academic Article
|
Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.
|
|
Academic Article
|
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide.
|
|
Academic Article
|
Pulmonary lipopolysaccharide (LPS)-binding protein inhibits the LPS-induced lung inflammation in vivo.
|
|
Academic Article
|
The biology of Toll-like receptors.
|
|
Academic Article
|
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus.
|
|
Academic Article
|
Toll-like receptor 4 mediates intracellular signaling without TNF-alpha release in response to Cryptococcus neoformans polysaccharide capsule.
|
|
Academic Article
|
Extolling the diversity of bacterial endotoxins.
|
|
Academic Article
|
Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite.
|
|
Academic Article
|
Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling.
|
|
Academic Article
|
Lipoteichoic acid-induced lung inflammation depends on TLR2 and the concerted action of TLR4 and the platelet-activating factor receptor.
|
|
Academic Article
|
Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation.
|
|
Academic Article
|
Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4.
|
|
Academic Article
|
Structural requirements of muramylpeptides for induction of Toll-like receptor 2-mediated NF-kappaB activation in CHO cells.
|
|
Academic Article
|
TIRAP: how Toll receptors fraternize.
|
|
Academic Article
|
Recombinant Ov-ASP-1, a Th1-biased protein adjuvant derived from the helminth Onchocerca volvulus, can directly bind and activate antigen-presenting cells.
|
|
Academic Article
|
A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.
|
|
Academic Article
|
Mal connects TLR2 to PI3Kinase activation and phagocyte polarization.
|
|
Academic Article
|
MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3.
|
|
Academic Article
|
Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.
|
|
Academic Article
|
LBP, CD14, TLR4 and the murine innate immune response to a peritoneal Salmonella infection.
|
|
Academic Article
|
Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress.
|
|
Academic Article
|
Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation.
|
|
Academic Article
|
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
|
|
Academic Article
|
Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation.
|
|
Academic Article
|
The role of lipopolysaccharide binding protein in resistance to Salmonella infections in mice.
|
|
Academic Article
|
Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers.
|
|
Academic Article
|
Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways.
|
|
Academic Article
|
A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization.
|
|
Academic Article
|
Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice.
|
|
Academic Article
|
Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2.
|
|
Academic Article
|
The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism.
|
|
Academic Article
|
Heat-killed Brucella abortus induces TNF and IL-12p40 by distinct MyD88-dependent pathways: TNF, unlike IL-12p40 secretion, is Toll-like receptor 2 dependent.
|
|
Academic Article
|
Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling.
|
|
Academic Article
|
LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
|
|
Academic Article
|
Receptor "cross talk" in innate immunity.
|
|
Academic Article
|
Cell distributions and functions of Toll-like receptor 4 studied by fluorescent gene constructs.
|
|
Academic Article
|
Lipopolysaccharide binding protein is an essential component of the innate immune response to Escherichia coli peritonitis in mice.
|
|
Academic Article
|
TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
|
|
Academic Article
|
Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity.
|
|
Academic Article
|
Neither CD14 nor serum is absolutely necessary for activation of mononuclear phagocytes by bacterial lipopolysaccharide.
|
|
Academic Article
|
Dual role of TLR2 and myeloid differentiation factor 88 in a mouse model of invasive group B streptococcal disease.
|
|
Academic Article
|
Innate immune responses to Rhodococcus equi.
|
|
Academic Article
|
Mechanisms of TLR9 activation.
|
|
Academic Article
|
Cell activation by Toll-like receptors: role of LBP and CD14.
|
|
Academic Article
|
Introduction: Toll receptors come of age.
|
|
Academic Article
|
Endotoxin recognition and signal transduction by the TLR4/MD2-complex.
|
|
Academic Article
|
Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105.
|
|
Academic Article
|
Role of lipoteichoic acid in the phagocyte response to group B streptococcus.
|
|
Academic Article
|
A Leptospira interrogans enzyme with similarity to yeast Ste14p that methylates the 1-phosphate group of lipid A.
|
|
Academic Article
|
Inhibition of TLR-4/MD-2 signaling by RP105/MD-1.
|
|
Academic Article
|
NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.
|
|
Academic Article
|
MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.
|
|
Academic Article
|
Viral inhibitory peptide of TLR4, a peptide derived from vaccinia protein A46, specifically inhibits TLR4 by directly targeting MyD88 adaptor-like and TRIF-related adaptor molecule.
|
|
Academic Article
|
Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi.
|
|
Concept
|
Membrane Glycoproteins
|
|
Concept
|
Platelet Membrane Glycoproteins
|
|
Academic Article
|
Hemolysis-induced lethality involves inflammasome activation by heme.
|
|
Academic Article
|
A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling.
|
|
Academic Article
|
Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR.
|
|
Academic Article
|
Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.
|