| Item Type | Name |
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Academic Article
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Targeted deletion of the lipopolysaccharide (LPS)-binding protein gene leads to profound suppression of LPS responses ex vivo, whereas in vivo responses remain intact.
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Academic Article
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Lipopolysaccharide recognition, CD14, and lipopolysaccharide receptors.
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Academic Article
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Divergent response to LPS and bacteria in CD14-deficient murine macrophages.
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Academic Article
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Toll-like receptor 2-dependent inhibition of macrophage class II MHC expression and antigen processing by 19-kDa lipoprotein of Mycobacterium tuberculosis.
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Academic Article
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Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent.
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Academic Article
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LPS-binding proteins and receptors.
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Academic Article
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Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice.
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Academic Article
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Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways.
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Academic Article
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Use of a photoactivatable taxol analogue to identify unique cellular targets in murine macrophages: identification of murine CD18 as a major taxol-binding protein and a role for Mac-1 in taxol-induced gene expression.
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Academic Article
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Non-mannose-capped lipoarabinomannan induces lung inflammation via toll-like receptor 2.
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Academic Article
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LPS-binding protein-deficient mice have an impaired defense against Gram-negative but not Gram-positive pneumonia.
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Academic Article
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Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi.
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Academic Article
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Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation.
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Academic Article
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Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation.
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Academic Article
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MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection.
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Academic Article
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Lipopolysaccharide binding protein-deficient mice have a normal defense against pulmonary mycobacterial infection.
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Academic Article
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Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes.
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Academic Article
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MyD88-dependent pathways mediate resistance to Cryptosporidium parvum infection in mice.
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Academic Article
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Pulmonary lipopolysaccharide (LPS)-binding protein inhibits the LPS-induced lung inflammation in vivo.
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Academic Article
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The biology of Toll-like receptors.
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Academic Article
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A mechanism for neurodegeneration induced by group B streptococci through activation of the TLR2/MyD88 pathway in microglia.
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Academic Article
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Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus.
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Academic Article
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MD-2 expression is not required for cell surface targeting of Toll-like receptor 4 (TLR4).
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Academic Article
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A bacterial carbohydrate links innate and adaptive responses through Toll-like receptor 2.
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Academic Article
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Activation of TLR2 and TLR4 by glycosylphosphatidylinositols derived from Toxoplasma gondii.
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Academic Article
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Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite.
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Academic Article
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Bacterial fimbriae stimulate proinflammatory activation in the endothelium through distinct TLRs.
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Academic Article
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Lipoteichoic acid-induced lung inflammation depends on TLR2 and the concerted action of TLR4 and the platelet-activating factor receptor.
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Academic Article
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TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA.
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Academic Article
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Role of p38 and early growth response factor 1 in the macrophage response to group B streptococcus.
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Academic Article
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Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide.
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Academic Article
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MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3.
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Academic Article
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Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.
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Academic Article
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CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.
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Academic Article
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LBP, CD14, TLR4 and the murine innate immune response to a peritoneal Salmonella infection.
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Academic Article
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Activation of the NLRP3 inflammasome by group B streptococci.
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Academic Article
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Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production.
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Academic Article
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DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation.
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Academic Article
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An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
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Academic Article
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The role of lipopolysaccharide binding protein in resistance to Salmonella infections in mice.
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Academic Article
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Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways.
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Academic Article
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Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice.
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Academic Article
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CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
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Academic Article
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Heat-killed Brucella abortus induces TNF and IL-12p40 by distinct MyD88-dependent pathways: TNF, unlike IL-12p40 secretion, is Toll-like receptor 2 dependent.
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Academic Article
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IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts.
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Academic Article
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TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
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Academic Article
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Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity.
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Academic Article
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Dual role of TLR2 and myeloid differentiation factor 88 in a mouse model of invasive group B streptococcal disease.
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Academic Article
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Innate immune responses to Rhodococcus equi.
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Academic Article
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Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105.
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Academic Article
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Role of lipoteichoic acid in the phagocyte response to group B streptococcus.
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Academic Article
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Inhibition of TLR-4/MD-2 signaling by RP105/MD-1.
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Academic Article
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Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling.
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Academic Article
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HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.
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Academic Article
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MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals.
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Academic Article
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Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition.
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Academic Article
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Combinatorial pattern recognition receptor signaling alters the balance of life and death in macrophages.
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Academic Article
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MyD88-dependent activation of dendritic cells and CD4(+) T lymphocytes mediates symptoms, but is not required for the immunological control of parasites during rodent malaria.
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Academic Article
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MUC1 mucin is a negative regulator of toll-like receptor signaling.
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Academic Article
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Lymphocytic choriomeningitis virus (LCMV) infection of CNS glial cells results in TLR2-MyD88/Mal-dependent inflammatory responses.
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Academic Article
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Lipoproteins are critical TLR2 activating toxins in group B streptococcal sepsis.
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Academic Article
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Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi.
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Academic Article
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Alternating 2'-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist.
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Academic Article
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TLR2 mediates recognition of live Staphylococcus epidermidis and clearance of bacteremia.
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Academic Article
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TLR3-mediated IFN-? gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like.
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Academic Article
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MyD88-dependent pathway is essential for the innate immunity to Enterocytozoon bieneusi.
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Academic Article
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Toll-like receptors participate in macrophage activation and intracellular control of Leishmania (Viannia) panamensis.
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Academic Article
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Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi.
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Academic Article
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Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome.
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Academic Article
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NO is a macrophage autonomous modifier of the cytokine response to streptococcal single-stranded RNA.
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Academic Article
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Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins.
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Academic Article
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UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major.
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Academic Article
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Interferon-? and granulocyte/monocyte colony-stimulating factor production by natural killer cells involves different signaling pathways and the adaptor stimulator of interferon genes (STING).
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Concept
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Mice, Knockout
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Academic Article
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Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
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Academic Article
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TRIF signaling is essential for TLR4-driven IgE class switching.
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Academic Article
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Hemolysis-induced lethality involves inflammasome activation by heme.
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Academic Article
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MD-2 is required for disulfide HMGB1-dependent TLR4 signaling.
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Academic Article
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Involvement of Nod2 in the innate immune response elicited by malarial pigment hemozoin.
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Academic Article
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LXR Agonism Upregulates the Macrophage ABCA1/Syntrophin Protein Complex That Can Bind ApoA-I and Stabilized ABCA1 Protein, but Complex Loss Does Not Inhibit Lipid Efflux.
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Academic Article
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Type I Interferon Transcriptional Signature in Neutrophils and Low-Density Granulocytes Are Associated with Tissue Damage in Malaria.
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Academic Article
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A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling.
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Academic Article
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miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN).
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Academic Article
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Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice.
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Academic Article
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Microglia-derived ASC specks cross-seed amyloid-? in Alzheimer's disease.
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Academic Article
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Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.
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Academic Article
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Integrative analysis of microRNA and mRNA expression profiles of monocyte-derived dendritic cells differentiation during experimental cerebral malaria.
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Academic Article
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Clostridioides difficile Toxin A Remodels Membranes and Mediates DNA Entry Into Cells to Activate Toll-Like Receptor 9 Signaling.
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