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One or more keywords matched the following items that are connected to Golenbock, Douglas
Item TypeName
Academic Article Engagement of the Lewis X antigen (CD15) results in monocyte activation.
Academic Article Lipopolysaccharide antagonists.
Academic Article Targeted deletion of the lipopolysaccharide (LPS)-binding protein gene leads to profound suppression of LPS responses ex vivo, whereas in vivo responses remain intact.
Academic Article CD11/CD18 leukocyte integrins: new signaling receptors for bacterial endotoxin.
Academic Article CD11/CD18 and CD14 share a common lipid A signaling pathway.
Academic Article Heterotrimeric G proteins physically associated with the lipopolysaccharide receptor CD14 modulate both in vivo and in vitro responses to lipopolysaccharide.
Academic Article Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction.
Academic Article Lipopolysaccharide recognition, CD14, and lipopolysaccharide receptors.
Academic Article Cutting edge: cells that carry A null allele for toll-like receptor 2 are capable of responding to endotoxin.
Academic Article Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2.
Academic Article Bacterial lipopolysaccharide induces expression of the stress response genes hop and H411.
Academic Article Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis.
Academic Article Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.
Academic Article The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors.
Academic Article A novel synthetic acyclic lipid A-like agonist activates cells via the lipopolysaccharide/toll-like receptor 4 signaling pathway.
Academic Article Divergent response to LPS and bacteria in CD14-deficient murine macrophages.
Academic Article Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers.
Academic Article Structure and function of Toll-like receptor proteins.
Academic Article Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses.
Academic Article Membrane-associated proteins of a lipopolysaccharide-deficient mutant of Neisseria meningitidis activate the inflammatory response through toll-like receptor 2.
Academic Article Stimulation of macrophages by lipopolysaccharide alters the phosphorylation state, conformation, and function of PU.1 via activation of casein kinase II.
Academic Article Toll-like receptor 2-dependent inhibition of macrophage class II MHC expression and antigen processing by 19-kDa lipoprotein of Mycobacterium tuberculosis.
Academic Article Differential roles of TLR2 and TLR4 in the host response to Gram-negative bacteria: lessons from a lipopolysaccharide-deficient mutant of Neisseria meningitidis.
Academic Article Lipopolysaccharides from periodontopathic bacteria Porphyromonas gingivalis and Capnocytophaga ochracea are antagonists for human toll-like receptor 4.
Academic Article Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent.
Academic Article Innate immune recognition of lipopolysaccharide by endothelial cells.
Academic Article Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14.
Academic Article Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4.
Academic Article Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus.
Academic Article LPS-binding proteins and receptors.
Academic Article Construction of a lipopolysaccharide reporter cell line and its use in identifying mutants defective in endotoxin, but not TNF-alpha, signal transduction.
Academic Article Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
Academic Article Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice.
Academic Article Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells.
Academic Article Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection.
Academic Article IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
Academic Article Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.
Academic Article Adjuvants and their signaling pathways: beyond TLRs.
Academic Article The LPS receptor generates inflammatory signals from the cell surface.
Academic Article Membrane expression of soluble endotoxin-binding proteins permits lipopolysaccharide signaling in Chinese hamster ovary fibroblasts independently of CD14.
Academic Article Biological activities of Bacteroides forsythus lipoproteins and their possible pathological roles in periodontal disease.
Academic Article Relationship between structures and biological activities of mycoplasmal diacylated lipopeptides and their recognition by toll-like receptors 2 and 6.
Academic Article Use of a photoactivatable taxol analogue to identify unique cellular targets in murine macrophages: identification of murine CD18 as a major taxol-binding protein and a role for Mac-1 in taxol-induced gene expression.
Academic Article LPS-binding protein-deficient mice have an impaired defense against Gram-negative but not Gram-positive pneumonia.
Academic Article Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation.
Academic Article Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation.
Academic Article The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
Academic Article MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection.
Academic Article Human phagocytes have multiple lipid A-binding sites.
Academic Article Proinflammatory phenotype of vascular smooth muscle cells: role of efficient Toll-like receptor 4 signaling.
Academic Article Lipopolysaccharide binding protein-deficient mice have a normal defense against pulmonary mycobacterial infection.
Academic Article Human cardiac inflammatory responses triggered by Coxsackie B viruses are mainly Toll-like receptor (TLR) 8-dependent.
Academic Article The apoptotic response to pneumolysin is Toll-like receptor 4 dependent and protects against pneumococcal disease.
Academic Article Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes.
Academic Article Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.
Academic Article Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide.
Academic Article MyD88-dependent pathways mediate resistance to Cryptosporidium parvum infection in mice.
Academic Article Pulmonary lipopolysaccharide (LPS)-binding protein inhibits the LPS-induced lung inflammation in vivo.
Academic Article The biology of Toll-like receptors.
Academic Article A mechanism for neurodegeneration induced by group B streptococci through activation of the TLR2/MyD88 pathway in microglia.
Academic Article Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus.
Academic Article Toll-like receptor 4 mediates intracellular signaling without TNF-alpha release in response to Cryptococcus neoformans polysaccharide capsule.
Academic Article Toll-like receptor-dependent discrimination of streptococci.
Academic Article Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.
Academic Article Extolling the diversity of bacterial endotoxins.
Academic Article Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.
Academic Article Immunology. The shape of things to come.
Academic Article YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction.
Academic Article Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite.
Academic Article Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling.
Academic Article Phagocytosis and intracellular killing of MD-2 opsonized gram-negative bacteria depend on TLR4 signaling.
Academic Article Bacterial fimbriae stimulate proinflammatory activation in the endothelium through distinct TLRs.
Academic Article Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation.
Academic Article Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4.
Academic Article The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Academic Article Structural requirements of muramylpeptides for induction of Toll-like receptor 2-mediated NF-kappaB activation in CHO cells.
Academic Article TIRAP: how Toll receptors fraternize.
Academic Article Recombinant Ov-ASP-1, a Th1-biased protein adjuvant derived from the helminth Onchocerca volvulus, can directly bind and activate antigen-presenting cells.
Academic Article Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.
Academic Article Innate immune recognition of Yersinia pseudotuberculosis type III secretion.
Academic Article LBP, CD14, TLR4 and the murine innate immune response to a peritoneal Salmonella infection.
Academic Article Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation.
Academic Article Activation of the NLRP3 inflammasome by group B streptococci.
Academic Article Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production.
Academic Article Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation.
Academic Article The role of lipopolysaccharide binding protein in resistance to Salmonella infections in mice.
Academic Article Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers.
Academic Article Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways.
Academic Article A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization.
Academic Article NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Academic Article Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2.
Academic Article Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens.
Academic Article CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Academic Article Lipid A binding sites in membranes of macrophage tumor cells.
Academic Article The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism.
Academic Article Heat-killed Brucella abortus induces TNF and IL-12p40 by distinct MyD88-dependent pathways: TNF, unlike IL-12p40 secretion, is Toll-like receptor 2 dependent.
Academic Article Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling.
Academic Article LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
Academic Article Lipopolysaccharide binding protein is an essential component of the innate immune response to Escherichia coli peritonitis in mice.
Academic Article IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts.
Academic Article TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Academic Article Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity.
Academic Article Neither CD14 nor serum is absolutely necessary for activation of mononuclear phagocytes by bacterial lipopolysaccharide.
Academic Article Dual role of TLR2 and myeloid differentiation factor 88 in a mouse model of invasive group B streptococcal disease.
Academic Article Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway.
Academic Article Innate immune responses to Rhodococcus equi.
Academic Article The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades.
Academic Article Cell activation by Toll-like receptors: role of LBP and CD14.
Academic Article Introduction: Toll receptors come of age.
Academic Article Endotoxin recognition and signal transduction by the TLR4/MD2-complex.
Academic Article Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105.
Academic Article A Leptospira interrogans enzyme with similarity to yeast Ste14p that methylates the 1-phosphate group of lipid A.
Academic Article Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.
Academic Article Peptidoglycan recognition by the Drosophila Imd pathway.
Academic Article The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.
Academic Article Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling.
Academic Article MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals.
Academic Article Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition.
Academic Article MUC1 mucin is a negative regulator of toll-like receptor signaling.
Academic Article Lymphocytic choriomeningitis virus (LCMV) infection of CNS glial cells results in TLR2-MyD88/Mal-dependent inflammatory responses.
Academic Article Lipoproteins are critical TLR2 activating toxins in group B streptococcal sepsis.
Academic Article IL-10 enhances MD-2 and CD14 expression in monocytes and the proteins are increased and correlated in HIV-infected patients.
Academic Article TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway.
Academic Article Inflammasomes: too big to miss.
Academic Article Viral inhibitory peptide of TLR4, a peptide derived from vaccinia protein A46, specifically inhibits TLR4 by directly targeting MyD88 adaptor-like and TRIF-related adaptor molecule.
Academic Article UNC93B1 mediates host resistance to infection with Toxoplasma gondii.
Academic Article TLR3-mediated IFN-? gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like.
Academic Article Macrophages recognize streptococci through bacterial single-stranded RNA.
Academic Article Toll-like receptors participate in macrophage activation and intracellular control of Leishmania (Viannia) panamensis.
Academic Article Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi.
Academic Article Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome.
Academic Article NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1? and neuronal toxicity.
Academic Article Toll-like receptor (TLR) 2 mediates inflammatory responses to oligomerized RrgA pneumococcal pilus type 1 protein.
Academic Article Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins.
Academic Article UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major.
Academic Article The Abi-domain protein Abx1 interacts with the CovS histidine kinase to control virulence gene expression in group B Streptococcus.
Academic Article Interferon-? and granulocyte/monocyte colony-stimulating factor production by natural killer cells involves different signaling pathways and the adaptor stimulator of interferon genes (STING).
Academic Article CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide.
Academic Article CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognition.
Concept Membrane Proteins
Concept Hemolysin Proteins
Concept DNA-Binding Proteins
Concept Heat-Shock Proteins
Concept ADAM Proteins
Concept Muscle Proteins
Concept Phosphate-Binding Proteins
Concept HSP70 Heat-Shock Proteins
Concept GTP-Binding Proteins
Concept Helminth Proteins
Concept Carrier Proteins
Concept Luminescent Proteins
Concept Nuclear Proteins
Concept Recombinant Proteins
Concept Acute-Phase Proteins
Concept Intracellular Signaling Peptides and Proteins
Concept tau Proteins
Concept Dystrophin-Associated Proteins
Concept Viral Proteins
Concept Intercellular Signaling Peptides and Proteins
Concept HSP90 Heat-Shock Proteins
Concept rab GTP-Binding Proteins
Concept Pulmonary Surfactant-Associated Proteins
Concept Bone Morphogenetic Proteins
Concept Myelin Proteins
Concept Proto-Oncogene Proteins c-akt
Concept Proteins
Concept Viral Core Proteins
Concept Membrane Transport Proteins
Concept Cytoskeletal Proteins
Concept Adaptor Proteins, Signal Transducing
Concept Green Fluorescent Proteins
Concept Bacterial Proteins
Concept Recombinant Fusion Proteins
Concept Calcium-Binding Proteins
Concept Bacterial Outer Membrane Proteins
Concept Viral Nonstructural Proteins
Concept Opsonin Proteins
Concept Fungal Proteins
Concept Saccharomyces cerevisiae Proteins
Concept Proto-Oncogene Proteins c-jun
Concept Drosophila Proteins
Concept Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
Concept Insect Proteins
Concept Viral Fusion Proteins
Concept Adaptor Proteins, Vesicular Transport
Concept Apoptosis Regulatory Proteins
Concept Cation Transport Proteins
Concept Proto-Oncogene Proteins
Concept Blood Proteins
Concept Viral Envelope Proteins
Concept Protozoan Proteins
Concept Fimbriae Proteins
Concept CARD Signaling Adaptor Proteins
Academic Article The genome of Anopheles darlingi, the main neotropical malaria vector.
Academic Article Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection.
Academic Article Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
Academic Article Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
Academic Article TRIF signaling is essential for TLR4-driven IgE class switching.
Academic Article Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome.
Academic Article RNA and ?-hemolysin of group B Streptococcus induce interleukin-1? (IL-1?) by activating NLRP3 inflammasomes in mouse macrophages.
Academic Article Hemolysis-induced lethality involves inflammasome activation by heme.
Academic Article Metalloproteinase-dependent TLR2 ectodomain shedding is involved in soluble toll-like receptor 2 (sTLR2) production.
Academic Article LXR Agonism Upregulates the Macrophage ABCA1/Syntrophin Protein Complex That Can Bind ApoA-I and Stabilized ABCA1 Protein, but Complex Loss Does Not Inhibit Lipid Efflux.
Academic Article A Novel Factor H-Fc Chimeric Immunotherapeutic Molecule against Neisseria gonorrhoeae.
Academic Article Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4.
Academic Article A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In Vivo Infection.
Academic Article Group B Streptococcus Degrades Cyclic-di-AMP to Modulate STING-Dependent Type I Interferon Production.
Academic Article miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN).
Academic Article Cyclic GMP-AMP Synthase Is the Cytosolic Sensor of Plasmodium falciparum Genomic DNA and Activates Type I IFN in Malaria.
Academic Article Activation of the NLRP3 inflammasome in microglia: the role of ceramide.
Academic Article Microglia-derived ASC specks cross-seed amyloid-? in Alzheimer's disease.
Academic Article The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2.
Academic Article Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR.
Academic Article NLRP3 inflammasome activation drives tau pathology.
Concept Prion Proteins
Concept Myelin and Lymphocyte-Associated Proteolipid Proteins
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