Item Type | Name |
Academic Article
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Diverse regulation of NF-kappaB and peroxisome proliferator-activated receptors in murine nonalcoholic fatty liver.
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Academic Article
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Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation.
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Academic Article
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Subversion of plasmacytoid and myeloid dendritic cell functions in chronic HCV infection.
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Academic Article
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Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes.
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Academic Article
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RSA 2004: combined basic research satellite symposium - session four: hepatitis virus and alcohol interactions in immunity and liver disease.
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Academic Article
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Acute ethanol treatment modulates Toll-like receptor-4 association with lipid rafts.
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Academic Article
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Hepatitis C virus NS5A protein--a master regulator?
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Academic Article
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TLR2- and TLR4-mediated signals determine attenuation or augmentation of inflammation by acute alcohol in monocytes.
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Academic Article
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The emerging role of toll-like receptor pathways in surgical diseases.
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Academic Article
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Critical role of toll-like receptors and the common TLR adaptor, MyD88, in induction of granulomas and liver injury.
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Academic Article
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Hepatitis C virus infection--pathobiology and implications for new therapeutic options.
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Academic Article
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Innate immune response and hepatic inflammation.
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Academic Article
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T cells with regulatory activity in hepatitis C virus infection: what we know and what we don't.
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Academic Article
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The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88.
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Academic Article
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A recent perspective on alcohol, immunity, and host defense.
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Academic Article
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Antigen-presenting cells under the influence of alcohol.
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Academic Article
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In vitro and in vivo models of acute alcohol exposure.
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Academic Article
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Alcohol-induced modulation of signaling pathways in liver parenchymal and nonparenchymal cells: implications for immunity.
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Academic Article
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Signalling pathways in alcohol-induced liver inflammation.
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Academic Article
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MicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced nonalcoholic steatohepatitis models in mice.
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Academic Article
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Identification and characterization of broadly neutralizing human monoclonal antibodies directed against the E2 envelope glycoprotein of hepatitis C virus.
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Academic Article
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Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice.
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Academic Article
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Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor {alpha} (TNF{alpha}) production via increased mRNA half-life in alcoholic liver disease.
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Academic Article
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Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice.
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Academic Article
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Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells.
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Academic Article
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Hepatocyte-specific hypoxia-inducible factor-1a is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice.
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Academic Article
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Gut-liver axis and sensing microbes.
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Academic Article
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Ethanol-mediated regulation of transcription factors in immunocompetent cells.
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Academic Article
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The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.
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Academic Article
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Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases.
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Academic Article
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Plasma microRNA profiles distinguish lethal injury in acetaminophen toxicity: a research study.
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Academic Article
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IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice.
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Academic Article
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Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees.
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Academic Article
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Innate immunity and alcoholic liver disease.
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Academic Article
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Reply: To PMID 22684891.
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Academic Article
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Acute alcohol inhibits the induction of nuclear regulatory factor kappa B activation through CD14/toll-like receptor 4, interleukin-1, and tumor necrosis factor receptors: a common mechanism independent of inhibitory kappa B alpha degradation?
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Academic Article
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Modulation of immunity and viral-host interactions by alcohol.
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Academic Article
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Toll-like receptors in liver disease.
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Academic Article
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Chronic alcohol-induced microRNA-155 contributes to neuroinflammation in a TLR4-dependent manner in mice.
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Academic Article
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Selective priming to Toll-like receptor 4 (TLR4), not TLR2, ligands by P. acnes involves up-regulation of MD-2 in mice.
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Academic Article
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Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression.
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Academic Article
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RSA 2004: combined basic research satellite symposium - session two: toll-like receptors and organ damage.
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Academic Article
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RSA 2004: combined basic research satellite symposium - session three: alcohol and mitochondrial metabolism: at the crossroads of life and death.
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Academic Article
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Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: the role of toll-like receptors 2 and 4.
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Academic Article
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Hepatitis C infection and alcohol use: A dangerous mix for the liver and antiviral immunity.
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Academic Article
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Cytokines and alcohol.
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Academic Article
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Pattern recognition receptors: a contemporary view on liver diseases.
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Academic Article
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Heme oxygenase-1 mediates the anti-inflammatory effects of acute alcohol on IL-10 induction involving p38 MAPK activation in monocytes.
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Academic Article
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Acute and chronic alcohol abuse modulate immunity.
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Academic Article
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Acute alcohol exposure exerts anti-inflammatory effects by inhibiting IkappaB kinase activity and p65 phosphorylation in human monocytes.
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Academic Article
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Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.
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Academic Article
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The role of plasmacytoid dendritic cell-derived IFN alpha in antiviral immunity.
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Academic Article
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Hepatitis C and innate immunity: recent advances.
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Academic Article
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Bone marrow-derived immune cells mediate sensitization to liver injury in a myeloid differentiation factor 88-dependent fashion.
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Academic Article
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VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice.
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Academic Article
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Alcoholic liver disease and the gut-liver axis.
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Academic Article
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Alcohol and hepatitis C virus--interactions in immune dysfunctions and liver damage.
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Academic Article
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Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells.
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Academic Article
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Dendritic cells in hepatitis C infection: can they (help) win the battle?
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Academic Article
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Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice.
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Academic Article
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An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice.
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Academic Article
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Hypoxia and hypoxia inducible factors: diverse roles in liver diseases.
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Academic Article
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Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver.
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Academic Article
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MicroRNA silencing and the development of novel therapies for liver disease.
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Academic Article
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Induction of Bcl-3 by acute binge alcohol results in toll-like receptor 4/LPS tolerance.
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Academic Article
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Binge ethanol and liver: new molecular developments.
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Academic Article
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Focus on: Alcohol and the liver.
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Academic Article
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Alcohol-induced IL-1? in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.
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Academic Article
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IFN-? production by human natural killer cells in response to HCV-infected hepatoma cells is dependent on accessory cells.
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Concept
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Disease Models, Animal
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Concept
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Animals
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Concept
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Behavior, Animal
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Concept
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Models, Animal
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Academic Article
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STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease.
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Academic Article
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High fat diet feeding results in gender specific steatohepatitis and inflammasome activation.
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Academic Article
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Micro-RNA-155 deficiency prevents alcohol-induced serum endotoxin increase and small bowel inflammation in mice.
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Academic Article
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Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88-dependent manner in dietary steatohepatitis.
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Academic Article
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Exosome-mediated delivery of functionally active miRNA-155 inhibitor to macrophages.
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Academic Article
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Innate immune cell networking in hepatitis C virus infection.
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Academic Article
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Converging actions of alcohol on liver and brain immune signaling.
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Academic Article
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Alcohol and HCV: implications for liver cancer.
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Academic Article
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Gut-liver axis in alcoholic liver disease.
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Academic Article
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microRNA-122 regulates hypoxia-inducible factor-1 and vimentin in hepatocytes and correlates with fibrosis in diet-induced steatohepatitis.
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Academic Article
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Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS.
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Academic Article
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Biodistribution and function of extracellular miRNA-155 in mice.
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Academic Article
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MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis.
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Academic Article
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Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high fat-cholesterol-sugar diet model in mice.
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Academic Article
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Inflammasome activation and function in liver disease.
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Academic Article
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Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease.
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Academic Article
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Increased number of circulating exosomes and their microRNA cargos are potential novel biomarkers in alcoholic hepatitis.
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Academic Article
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Inflammasome activation in the liver: Focus on alcoholic and non-alcoholic steatohepatitis.
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Academic Article
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Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice.
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Academic Article
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Alcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and miR-122-mediated HIF-1a activation.
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Academic Article
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Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease.
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Academic Article
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The pro-inflammatory effects of miR-155 promote liver fibrosis and alcohol-induced steatohepatitis.
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Academic Article
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Therapeutic Benefits of Spleen Tyrosine Kinase Inhibitor Administration on Binge Drinking-Induced Alcoholic Liver Injury, Steatosis, and Inflammation in Mice.
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Academic Article
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Interleukin-1 and inflammasomes in alcoholic liver disease/acute alcoholic hepatitis and nonalcoholic fatty liver disease/nonalcoholic steatohepatitis.
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Academic Article
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Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease.
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Academic Article
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Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes.
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Academic Article
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Interleukin-1 inhibition facilitates recovery from liver injury and promotes regeneration of hepatocytes in alcoholic hepatitis in mice.
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Academic Article
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Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice.
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Academic Article
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Recovery of ethanol-induced Akkermansia muciniphila depletion ameliorates alcoholic liver disease.
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Academic Article
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Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease.
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Academic Article
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Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation through heat shock protein 90.
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Academic Article
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MicroRNA 122, Regulated by GRLH2, Protects Livers of Mice and?Patients From Ethanol-Induced Liver Disease.
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Academic Article
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IL-1a in acetaminophen toxicity: a sterile danger signal.
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Academic Article
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Hypoxia downregulates protein S expression.
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Academic Article
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Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use.
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Academic Article
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Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol-Induced Liver Damage, Steatosis, and Inflammation in Mice.
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Academic Article
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Macrophage-Specific Hypoxia-Inducible Factor-1a Contributes to Impaired Autophagic Flux in Nonalcoholic Steatohepatitis.
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Academic Article
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Alcoholic Liver Disease Accelerates Early Hepatocellular Cancer in a?Mouse Model.
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Academic Article
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Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression.
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Academic Article
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Non-invasive diagnosis and biomarkers in alcohol-related liver disease.
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Academic Article
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Dysregulated Autophagy and Lysosome Function Are Linked to Exosome Production by Micro-RNA 155 in Alcoholic Liver Disease.
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Academic Article
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Inhibition of the Inflammasome Signaling Cascade Reduces Alcohol Consumption in Female But Not Male Mice.
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Academic Article
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Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations.
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Academic Article
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Immunopathobiology and therapeutic targets related to cytokines in liver diseases.
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Academic Article
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Steatosis, inflammasome upregulation, and fibrosis are attenuated in miR-155 deficient mice in a high fat-cholesterol-sugar diet-induced model of NASH.
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Academic Article
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Extracellular vesicles in inflammation: Focus on the microRNA cargo of EVs in modulation of liver diseases.
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Academic Article
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Differential role of MLKL in alcohol-associated and non-alcohol-associated fatty liver diseases in mice and humans.
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Academic Article
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Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice.
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Academic Article
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Altered ethanol metabolism and increased oxidative stress enhance alcohol-associated liver injury in farnesoid X receptor-deficient mice.
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Academic Article
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Transcriptional regulation of Acsl1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation.
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Academic Article
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Neutrophil extracellular traps contribute to liver damage and increase defective low-density neutrophils in alcohol-associated hepatitis.
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Academic Article
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Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation.
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Academic Article
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Protective role of cGAS in NASH is related to the maintenance of intestinal homeostasis.
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Academic Article
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Bile acid-induced IRF3 phosphorylation mediates cell death, inflammatory responses, and fibrosis in cholestasis-induced liver and kidney injury via regulation of ZBP1.
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Academic Article
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Reply: How does bile acid-induced IRF3 phosphorylation mediate cholestatic liver and kidney injury?-More needs to be known.
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Academic Article
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Combined Insults of a MASH Diet and Alcohol Binges Activate Intercellular Communication and Neutrophil Recruitment via the NLRP3-IL-1? Axis in the Liver.
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Academic Article
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A novel experimental model of MetALD in male mice recapitulates key features of severe alcohol-associated hepatitis.
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Academic Article
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Inflammasomes in chronic liver disease: Hepatic injury, fibrosis progression and systemic inflammation.
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Academic Article
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Alcohol-Associated Liver Disease Outcomes: Critical Mechanisms of Liver Injury Progression.
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Academic Article
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Neutrophil extracellular traps activate hepatic stellate cells and monocytes via NLRP3 sensing in alcohol-induced acceleration of MASH fibrosis.
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Academic Article
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In vivo Bruton's tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis.
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Academic Article
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IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer's disease.
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