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Academic Article
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FcgammaR cross-linking mediates NF-kappaB activation, reduced antigen presentation capacity, and decreased IL-12 production in monocytes without modulation of myeloid dendritic cell development.
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Academic Article
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Diverse regulation of NF-kappaB and peroxisome proliferator-activated receptors in murine nonalcoholic fatty liver.
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Academic Article
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Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes.
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Academic Article
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Moderate alcohol intake in humans attenuates monocyte inflammatory responses: inhibition of nuclear regulatory factor kappa B and induction of interleukin 10.
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Academic Article
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TLR2- and TLR4-mediated signals determine attenuation or augmentation of inflammation by acute alcohol in monocytes.
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Academic Article
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Critical role of toll-like receptors and the common TLR adaptor, MyD88, in induction of granulomas and liver injury.
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Academic Article
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Viral and host factors induce macrophage activation and loss of toll-like receptor tolerance in chronic HCV infection.
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Academic Article
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The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88.
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Academic Article
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Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice.
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Academic Article
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Alcohol exposure as a risk factor for adverse outcomes in elective surgery.
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Academic Article
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Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor {alpha} (TNF{alpha}) production via increased mRNA half-life in alcoholic liver disease.
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Academic Article
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Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice.
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Academic Article
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Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells.
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Academic Article
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Hepatocyte-specific hypoxia-inducible factor-1a is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice.
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Academic Article
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Ethanol-mediated regulation of transcription factors in immunocompetent cells.
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Academic Article
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Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes.
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Academic Article
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Acute alcohol inhibits the induction of nuclear regulatory factor kappa B activation through CD14/toll-like receptor 4, interleukin-1, and tumor necrosis factor receptors: a common mechanism independent of inhibitory kappa B alpha degradation?
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Academic Article
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Chronic alcohol-induced microRNA-155 contributes to neuroinflammation in a TLR4-dependent manner in mice.
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Academic Article
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Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression.
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Academic Article
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Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: the role of toll-like receptors 2 and 4.
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Academic Article
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Cytokines and alcohol.
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Academic Article
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Acute alcohol exposure exerts anti-inflammatory effects by inhibiting IkappaB kinase activity and p65 phosphorylation in human monocytes.
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Academic Article
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Acute alcohol activates STAT3, AP-1, and Sp-1 transcription factors via the family of Src kinases to promote IL-10 production in human monocytes.
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Academic Article
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Effect of ethanol on inflammatory responses. Implications for pancreatitis.
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Academic Article
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Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.
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Academic Article
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Acute alcohol intake induces SOCS1 and SOCS3 and inhibits cytokine-induced STAT1 and STAT3 signaling in human monocytes.
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Academic Article
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Bone marrow-derived immune cells mediate sensitization to liver injury in a myeloid differentiation factor 88-dependent fashion.
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Academic Article
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VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice.
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Academic Article
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The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes.
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Academic Article
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Impaired expression and function of toll-like receptor 7 in hepatitis C virus infection in human hepatoma cells.
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Academic Article
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Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells.
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Academic Article
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Hypoxia and hypoxia inducible factors: diverse roles in liver diseases.
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Academic Article
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Increased microRNA-155 expression in the serum and peripheral monocytes in chronic HCV infection.
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Concept
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Granulocyte Colony-Stimulating Factor
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Concept
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Transforming Growth Factor beta
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Concept
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Myeloid Differentiation Factor 88
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Concept
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Interferon Regulatory Factor-7
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Concept
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STAT3 Transcription Factor
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Concept
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Hypoxia-Inducible Factor 1
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Concept
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Tumor Necrosis Factor-alpha
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Concept
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Transforming Growth Factor beta1
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Concept
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Interferon Regulatory Factor-3
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Concept
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Transcription Factor AP-1
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Concept
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Complement Factor B
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Concept
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Receptors, Tumor Necrosis Factor, Type I
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Concept
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Complement Factor D
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Concept
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Sp1 Transcription Factor
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Concept
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STAT1 Transcription Factor
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Concept
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Receptors, Tumor Necrosis Factor
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Concept
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Transcription Factor RelA
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Concept
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Hypoxia-Inducible Factor 1, alpha Subunit
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Academic Article
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STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease.
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Academic Article
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Acute binge drinking increases serum endotoxin and bacterial DNA levels in healthy individuals.
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Academic Article
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High fat diet feeding results in gender specific steatohepatitis and inflammasome activation.
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Academic Article
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Micro-RNA-155 deficiency prevents alcohol-induced serum endotoxin increase and small bowel inflammation in mice.
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Academic Article
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Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88-dependent manner in dietary steatohepatitis.
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Academic Article
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microRNA-122 regulates hypoxia-inducible factor-1 and vimentin in hepatocytes and correlates with fibrosis in diet-induced steatohepatitis.
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Academic Article
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MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis.
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Academic Article
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Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease.
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Academic Article
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MicroRNA Cargo of Extracellular Vesicles from Alcohol-exposed Monocytes Signals Naive Monocytes to Differentiate into M2 Macrophages.
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Academic Article
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Alcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and miR-122-mediated HIF-1a activation.
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Academic Article
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Therapeutic Benefits of Spleen Tyrosine Kinase Inhibitor Administration on Binge Drinking-Induced Alcoholic Liver Injury, Steatosis, and Inflammation in Mice.
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Academic Article
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Kr?ppel-like factor 4 is a transcriptional regulator of M1/M2 macrophage polarization in alcoholic liver disease.
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Academic Article
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Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes.
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Academic Article
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Hypoxia downregulates protein S expression.
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Academic Article
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Macrophage-Specific Hypoxia-Inducible Factor-1a Contributes to Impaired Autophagic Flux in Nonalcoholic Steatohepatitis.
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Academic Article
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Diagnostic and Prognostic Significance of Complement in Patients With Alcohol-Associated Hepatitis.
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Academic Article
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Granulocyte colony-stimulating factor attenuates liver damage by M2 macrophage polarization and hepatocyte proliferation in alcoholic hepatitis in mice.
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Academic Article
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Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation.
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Academic Article
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Bile acid-induced IRF3 phosphorylation mediates cell death, inflammatory responses, and fibrosis in cholestasis-induced liver and kidney injury via regulation of ZBP1.
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Academic Article
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Reply: How does bile acid-induced IRF3 phosphorylation mediate cholestatic liver and kidney injury?-More needs to be known.
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Academic Article
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Proteomics identifies complement protein signatures in patients with alcohol-associated hepatitis.
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Academic Article
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IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer's disease.
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