| Item Type | Name |
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Academic Article
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Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation.
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Academic Article
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Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes.
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Academic Article
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Critical role of toll-like receptors and the common TLR adaptor, MyD88, in induction of granulomas and liver injury.
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Academic Article
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The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88.
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Academic Article
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MicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced nonalcoholic steatohepatitis models in mice.
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Academic Article
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Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice.
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Academic Article
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Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor {alpha} (TNF{alpha}) production via increased mRNA half-life in alcoholic liver disease.
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Academic Article
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Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice.
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Academic Article
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Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells.
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Academic Article
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The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.
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Academic Article
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Plasma microRNA profiles distinguish lethal injury in acetaminophen toxicity: a research study.
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Academic Article
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IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice.
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Academic Article
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Selective priming to Toll-like receptor 4 (TLR4), not TLR2, ligands by P. acnes involves up-regulation of MD-2 in mice.
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Academic Article
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Heme oxygenase-1 mediates the anti-inflammatory effects of acute alcohol on IL-10 induction involving p38 MAPK activation in monocytes.
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Academic Article
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Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.
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Academic Article
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VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice.
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Academic Article
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Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells.
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Academic Article
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Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice.
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Academic Article
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An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice.
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Academic Article
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Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver.
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Academic Article
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Induction of Bcl-3 by acute binge alcohol results in toll-like receptor 4/LPS tolerance.
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Academic Article
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Alcohol-induced IL-1? in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.
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Concept
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Mice, Inbred C57BL
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Academic Article
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High fat diet feeding results in gender specific steatohepatitis and inflammasome activation.
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Academic Article
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Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS.
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Academic Article
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MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis.
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Academic Article
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Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high fat-cholesterol-sugar diet model in mice.
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Academic Article
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Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease.
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Academic Article
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Increased number of circulating exosomes and their microRNA cargos are potential novel biomarkers in alcoholic hepatitis.
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Academic Article
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Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice.
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Academic Article
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Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease.
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Academic Article
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The pro-inflammatory effects of miR-155 promote liver fibrosis and alcohol-induced steatohepatitis.
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Academic Article
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Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease.
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Academic Article
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Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes.
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Academic Article
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Interleukin-1 inhibition facilitates recovery from liver injury and promotes regeneration of hepatocytes in alcoholic hepatitis in mice.
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Academic Article
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Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice.
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Academic Article
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Recovery of ethanol-induced Akkermansia muciniphila depletion ameliorates alcoholic liver disease.
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Academic Article
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Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease.
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Academic Article
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Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation through heat shock protein 90.
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Academic Article
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Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use.
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Academic Article
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Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol-Induced Liver Damage, Steatosis, and Inflammation in Mice.
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Academic Article
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Macrophage-Specific Hypoxia-Inducible Factor-1a Contributes to Impaired Autophagic Flux in Nonalcoholic Steatohepatitis.
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Academic Article
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Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression.
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Academic Article
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Dysregulated Autophagy and Lysosome Function Are Linked to Exosome Production by Micro-RNA 155 in Alcoholic Liver Disease.
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Academic Article
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Inhibition of the Inflammasome Signaling Cascade Reduces Alcohol Consumption in Female But Not Male Mice.
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Academic Article
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Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations.
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Academic Article
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Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice.
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Academic Article
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Altered ethanol metabolism and increased oxidative stress enhance alcohol-associated liver injury in farnesoid X receptor-deficient mice.
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Academic Article
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Protective role of cGAS in NASH is related to the maintenance of intestinal homeostasis.
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Academic Article
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Combined Insults of a MASH Diet and Alcohol Binges Activate Intercellular Communication and Neutrophil Recruitment via the NLRP3-IL-1? Axis in the Liver.
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Academic Article
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A novel experimental model of MetALD in male mice recapitulates key features of severe alcohol-associated hepatitis.
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Academic Article
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Neutrophil extracellular traps activate hepatic stellate cells and monocytes via NLRP3 sensing in alcohol-induced acceleration of MASH fibrosis.
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Academic Article
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In vivo Bruton's tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis.
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Academic Article
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IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer's disease.
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