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Search Results to Lila M Gierasch Ph.D.

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One or more keywords matched the following items that are connected to Gierasch, Lila

Item TypeName
Academic Article Molecular chaperones: clamps for the Clps?
Academic Article Different conformations for the same polypeptide bound to chaperones DnaK and GroEL.
Academic Article Biophysical studies of recognition sequences for targeting and folding.
Academic Article The cost of exposing a hydrophobic loop and implications for the functional role of 4.5 S RNA in the Escherichia coli signal recognition particle.
Academic Article Caught in the act: how ATP binding triggers cooperative conformational changes in a molecular machine.
Academic Article Domain interactions in E. coli SRP: stabilization of M domain by RNA is required for effective signal sequence modulation of NG domain.
Academic Article Functionally significant mobile regions of Escherichia coli SecA ATPase identified by NMR.
Academic Article Mutations in the substrate binding domain of the Escherichia coli 70 kDa molecular chaperone, DnaK, which alter substrate affinity or interdomain coupling.
Academic Article A peptide corresponding to an export-defective mutant OmpA signal sequence with asparagine in the hydrophobic core is unable to insert into model membranes.
Academic Article Extended polyglutamine tracts cause aggregation and structural perturbation of an adjacent beta barrel protein.
Academic Article Structural insights into substrate binding by the molecular chaperone DnaK.
Academic Article Multiple roles of prolyl residues in structure and folding.
Academic Article The structure of Escherichia coli signal recognition particle revealed by scanning transmission electron microscopy.
Academic Article From the test tube to the cell: exploring the folding and aggregation of a beta-clam protein.
Academic Article Functional signal peptides bind a soluble N-terminal fragment of SecA and inhibit its ATPase activity.
Academic Article Cross-strand split tetra-Cys motifs as structure sensors in a beta-sheet protein.
Academic Article Comparison of helix stability in wild-type and mutant LamB signal sequences.
Academic Article Defining the structure of the substrate-free state of the DnaK molecular chaperone.
Academic Article Exploring the interactions between signal sequences and E. coli SRP by two distinct and complementary crosslinking methods.
Academic Article The chaperonin GroEL binds a polypeptide in an alpha-helical conformation.
Academic Article Segmental isotopic labeling of the Hsp70 molecular chaperone DnaK using expressed protein ligation.
Academic Article Allosteric signal transmission in the nucleotide-binding domain of 70-kDa heat shock protein (Hsp70) molecular chaperones.
Academic Article FoldEco: a model for proteostasis in E. coli.
Academic Article A new twist for an Hsp70 chaperone.
Academic Article Phospholipid-induced monomerization and signal-peptide-induced oligomerization of SecA.
Academic Article Conformation-function relationships in hydrophobic peptides: interior turns and signal sequences.
Academic Article Interaction of peptides corresponding to mitochondrial presequences with membranes.
Academic Article Exploring the conformational roles of signal sequences: synthesis and conformational analysis of lambda receptor protein wild-type and mutant signal peptides.
Academic Article Effect of charged residue substitutions on the membrane-interactive properties of signal sequences of the Escherichia coli LamB protein.
Academic Article Effect of charged residue substitutions on the thermodynamics of signal peptide-lipid interactions for the Escherichia coli LamB signal sequence.
Academic Article Reorganization of lipid domain structure in membranes by a transmembrane peptide: an ESR spin label study on the effect of the Escherichia coli outer membrane protein A signal peptide on the fluid lipid domain connectivity in binary mixtures of dimyristoyl phosphatidylcholine and distearoyl phosphatidylcholine.
Academic Article GTP binding and hydrolysis by the signal recognition particle during initiation of protein translocation.
Academic Article Membrane-bound conformation of a signal peptide: a transferred nuclear Overhauser effect analysis.
Academic Article Conformational behavior of Escherichia coli OmpA signal peptides in membrane mimetic environments.
Academic Article The conformation of a signal peptide bound by Escherichia coli preprotein translocase SecA.
Academic Article Fluorescence analysis of tryptophan-containing variants of the LamB signal sequence upon insertion into a lipid bilayer.
Academic Article Inhibition of protein aggregation in vitro and in vivo by a natural osmoprotectant.
Academic Article Hsp70 chaperone ligands control domain association via an allosteric mechanism mediated by the interdomain linker.
Academic Article Electrophysiological studies in Xenopus oocytes for the opening of Escherichia coli SecA-dependent protein-conducting channels.
Academic Article Effects of osmolytes on protein folding and aggregation in cells.
Academic Article In-cell aggregation of a polyglutamine-containing chimera is a multistep process initiated by the flanking sequence.
Academic Article Chapter 3: A fluorescent window into protein folding and aggregation in cells.
Academic Article A method for direct measurement of protein stability in vivo.
Academic Article Post-reductionist protein science, or putting Humpty Dumpty back together again.
Academic Article Conformations and orientations of a signal peptide interacting with phospholipid monolayers.
Academic Article Role of Hsp70 ATPase domain intrinsic dynamics and sequence evolution in enabling its functional interactions with NEFs.
Academic Article An interdomain sector mediating allostery in Hsp70 molecular chaperones.
Academic Article Functional and nonfunctional LamB signal sequences can be distinguished by their biophysical properties.
Academic Article Conserved, disordered C terminus of DnaK enhances cellular survival upon stress and DnaK in vitro chaperone activity.
Academic Article Exploring weak, transient protein--protein interactions in crowded in vivo environments by in-cell nuclear magnetic resonance spectroscopy.
Academic Article Using a low denaturant model to explore the conformational features of translocation-active SecA.
Academic Article An interdomain energetic tug-of-war creates the allosterically active state in Hsp70 molecular chaperones.
Academic Article Early folding events protect aggregation-prone regions of a ß-rich protein.
Academic Article How bacteria survive an acid trip.
Academic Article In vivo function and membrane binding properties are correlated for Escherichia coli lamB signal peptides.
Academic Article Protein translocation into Escherichia coli membrane vesicles is inhibited by functional synthetic signal peptides.
Academic Article Characterization of a functionally important mobile domain of GroES.
Academic Article The structure of Escherichia coli heat-stable enterotoxin b by nuclear magnetic resonance and circular dichroism.
Concept Escherichia coli
Concept Escherichia coli Proteins
Academic Article Individual and collective contributions of chaperoning and degradation to protein homeostasis in E. coli.
Academic Article Substrate-binding domain conformational dynamics mediate Hsp70 allostery.
Academic Article Expression and Purification of Active Recombinant Human Alpha-1 Antitrypsin (AAT) from Escherichia coli.

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