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One or more keywords matched the following items that are connected to Gierasch, Lila
Item TypeName
Academic Article Molecular chaperones: clamps for the Clps?
Academic Article Constrained peptides: models of bioactive peptides and protein substructures.
Academic Article Renaturation of citrate synthase: influence of denaturant and folding assistants.
Academic Article Dynamics of cellular retinoic acid binding protein I on multiple time scales with implications for ligand binding.
Academic Article Mutating the charged residues in the binding pocket of cellular retinoic acid-binding protein simultaneously reduces its binding affinity to retinoic acid and increases its thermostability.
Academic Article Keeping it in the family: folding studies of related proteins.
Academic Article The cost of exposing a hydrophobic loop and implications for the functional role of 4.5 S RNA in the Escherichia coli signal recognition particle.
Academic Article Caught in the act: how ATP binding triggers cooperative conformational changes in a molecular machine.
Academic Article The LDL receptor clustering motif interacts with the clathrin terminal domain in a reverse turn conformation.
Academic Article Solution conformations of two flexible cyclic pentapeptides: cyclo(Gly-Pro-D-Phe-Gly-Ala) and cyclo(Gly-Pro-D-Phe-Gly-Val).
Academic Article Mutations in the substrate binding domain of the Escherichia coli 70 kDa molecular chaperone, DnaK, which alter substrate affinity or interdomain coupling.
Academic Article Sequence and structural analysis of cellular retinoic acid-binding proteins reveals a network of conserved hydrophobic interactions.
Academic Article Local sequence information in cellular retinoic acid-binding protein I: specific residue roles in beta-turns.
Academic Article Unfolding dynamics of a beta-sheet protein studied by mass spectrometry.
Academic Article Direct comparison of a stable isolated Hsp70 substrate-binding domain in the empty and substrate-bound states.
Academic Article Evolutionary coupling of structural and functional sequence information in the intracellular lipid-binding protein family.
Academic Article Structural insights into substrate binding by the molecular chaperone DnaK.
Academic Article Design of biologically active, conformationally constrained GnRH antagonists.
Academic Article Disorder breathes life into a DEAD motor.
Academic Article The structure of Escherichia coli signal recognition particle revealed by scanning transmission electron microscopy.
Academic Article From the test tube to the cell: exploring the folding and aggregation of a beta-clam protein.
Academic Article Use of synthetic signal sequences to explore the protein export machinery.
Academic Article Cyclic pentapeptides as models for reverse turns: determination of the equilibrium distribution between type I and type II conformations of Pro-Asn and Pro-Ala beta-turns.
Academic Article Cross-strand split tetra-Cys motifs as structure sensors in a beta-sheet protein.
Academic Article Sending signals dynamically.
Academic Article Native structural propensity in cellular retinoic acid-binding protein I 64-88: the role of locally encoded structure in the folding of a beta-barrel protein.
Academic Article Nuclear magnetic resonance analysis and conformational characterization of a cyclic decapeptide antagonist of gonadotropin-releasing hormone.
Academic Article The NPXY internalization signal of the LDL receptor adopts a reverse-turn conformation.
Academic Article Roles of beta-turns in protein folding: from peptide models to protein engineering.
Academic Article Rett syndrome-causing mutations in human MeCP2 result in diverse structural changes that impact folding and DNA interactions.
Academic Article The molecular dating game: an antibody heavy chain hangs loose with a chaperone while waiting for its life partner.
Academic Article Unique physical properties and interactions of the domains of methylated DNA binding protein 2.
Academic Article Dynamic local unfolding in the serpin a-1 antitrypsin provides a mechanism for loop insertion and polymerization.
Academic Article Turns in peptides and proteins.
Academic Article An interdomain energetic tug-of-war creates the allosterically active state in Hsp70 molecular chaperones.
Academic Article How bacteria survive an acid trip.
Academic Article The Role of Aromatic-Aromatic Interactions in Strand-Strand Stabilization of ?-Sheets.
Academic Article Conformations of (X-L-Pro-Y)2 cyclic hexapeptides. Preferred beta-turn conformers and implications for beta turns in proteins.
Academic Article Polypeptide interactions with molecular chaperones and their relationship to in vivo protein folding.
Academic Article Conformational analysis of a highly potent dicyclic gonadotropin-releasing hormone antagonist by nuclear magnetic resonance and molecular dynamics.
Academic Article Conformation of a heptapeptide substrate bound to protein farnesyltransferase.
Academic Article The structure of Escherichia coli heat-stable enterotoxin b by nuclear magnetic resonance and circular dichroism.
Concept Models, Molecular
Academic Article Delicate balance between functionally required flexibility and aggregation risk in a ?-rich protein.
Academic Article Comparing protein folding in vitro and in vivo: foldability meets the fitness challenge.
Academic Article ATPase subdomain IA is a mediator of interdomain allostery in Hsp70 molecular chaperones.
Academic Article Energy landscapes of functional proteins are inherently risky.
Academic Article How hsp70 molecular machines interact with their substrates to mediate diverse physiological functions.
Academic Article Substrate-binding domain conformational dynamics mediate Hsp70 allostery.
Academic Article Ligand-promoted protein folding by biased kinetic partitioning.
Academic Article Key features of an Hsp70 chaperone allosteric landscape revealed by ion-mobility native mass spectrometry and double electron-electron resonance.
Academic Article Allosteric landscapes of eukaryotic cytoplasmic Hsp70s are shaped by evolutionary tuning of key interfaces.
Academic Article Local and non-local topological information in the denatured state ensemble of a ?-barrel protein.
Academic Article The Hsp70 interdomain linker is a dynamic switch that enables allosteric communication between two structured domains.
Academic Article Kinetic versus thermodynamic control of mutational effects on protein homeostasis: A perspective from computational modeling and experiment.
Academic Article Hsp70 molecular chaperones: multifunctional allosteric holding and unfolding machines.
Academic Article Selective promiscuity in the binding of E. coli Hsp70 to an unfolded protein.
Academic Article Computationally-Aided Modeling of Hsp70-Client Interactions: Past, Present, and Future.
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  • Models Molecular