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Search Results to Lila M Gierasch Ph.D.

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One or more keywords matched the following items that are connected to Gierasch, Lila

Item TypeName
Academic Article The crystal structure of the GroES co-chaperonin at 2.8 A resolution.
Academic Article Signal sequences: the same yet different.
Academic Article Orientations of helical peptides in membrane bilayers by solid state NMR spectroscopy.
Academic Article Local interactions in a Schellman motif dictate interhelical arrangement in a protein fragment.
Academic Article Different conformations for the same polypeptide bound to chaperones DnaK and GroEL.
Academic Article Combined use of molecular dynamics simulations and NMR to explore peptide bond isomerization and multiple intramolecular hydrogen-bonding possibilities in a cyclic pentapeptide, cyclo(Gly-Pro-D-Phe-Gly-Val).
Academic Article Constrained peptides: models of bioactive peptides and protein substructures.
Academic Article Basis of substrate binding by the chaperonin GroEL.
Academic Article Mutating the charged residues in the binding pocket of cellular retinoic acid-binding protein simultaneously reduces its binding affinity to retinoic acid and increases its thermostability.
Academic Article The cost of exposing a hydrophobic loop and implications for the functional role of 4.5 S RNA in the Escherichia coli signal recognition particle.
Academic Article Domain interactions in E. coli SRP: stabilization of M domain by RNA is required for effective signal sequence modulation of NG domain.
Academic Article Solution conformations of two flexible cyclic pentapeptides: cyclo(Gly-Pro-D-Phe-Gly-Ala) and cyclo(Gly-Pro-D-Phe-Gly-Val).
Academic Article Impact of a micellar environment on the conformations of two cyclic pentapeptides.
Academic Article Functionally significant mobile regions of Escherichia coli SecA ATPase identified by NMR.
Academic Article Role of local sequence in the folding of cellular retinoic abinding protein I: structural propensities of reverse turns.
Academic Article Sequence and structural analysis of cellular retinoic acid-binding proteins reveals a network of conserved hydrophobic interactions.
Academic Article Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase.
Academic Article Evolutionary coupling of structural and functional sequence information in the intracellular lipid-binding protein family.
Academic Article Structural insights into substrate binding by the molecular chaperone DnaK.
Academic Article Design of biologically active, conformationally constrained GnRH antagonists.
Academic Article Functional signal peptides bind a soluble N-terminal fragment of SecA and inhibit its ATPase activity.
Academic Article Biophysical studies of signal peptides: implications for signal sequence functions and the involvement of lipid in protein export.
Academic Article Use of synthetic signal sequences to explore the protein export machinery.
Academic Article Cyclic pentapeptides as models for reverse turns: determination of the equilibrium distribution between type I and type II conformations of Pro-Asn and Pro-Ala beta-turns.
Academic Article Comparison of helix stability in wild-type and mutant LamB signal sequences.
Academic Article Exploring the interactions between signal sequences and E. coli SRP by two distinct and complementary crosslinking methods.
Academic Article T-cell antigenic peptides from sperm whale myoglobin fold as amphipathic helices: a possible determinant for immunodominance?
Academic Article The chaperonin GroEL binds a polypeptide in an alpha-helical conformation.
Academic Article Signal sequences.
Academic Article Mapping the signal sequence-binding site on SRP reveals a significant role for the NG domain.
Academic Article Phospholipid-induced monomerization and signal-peptide-induced oligomerization of SecA.
Academic Article Native structural propensity in cellular retinoic acid-binding protein I 64-88: the role of locally encoded structure in the folding of a beta-barrel protein.
Academic Article The NPXY internalization signal of the LDL receptor adopts a reverse-turn conformation.
Academic Article Interaction of peptides corresponding to mitochondrial presequences with membranes.
Academic Article Nonfarnesylated tetrapeptide inhibitors of protein farnesyltransferase.
Academic Article 1H and 15N resonance assignments and secondary structure of cellular retinoic acid-binding protein with and without bound ligand.
Academic Article Effect of charged residue substitutions on the membrane-interactive properties of signal sequences of the Escherichia coli LamB protein.
Academic Article Effect of charged residue substitutions on the thermodynamics of signal peptide-lipid interactions for the Escherichia coli LamB signal sequence.
Academic Article Reorganization of lipid domain structure in membranes by a transmembrane peptide: an ESR spin label study on the effect of the Escherichia coli outer membrane protein A signal peptide on the fluid lipid domain connectivity in binary mixtures of dimyristoyl phosphatidylcholine and distearoyl phosphatidylcholine.
Academic Article GTP binding and hydrolysis by the signal recognition particle during initiation of protein translocation.
Academic Article Membrane-bound conformation of a signal peptide: a transferred nuclear Overhauser effect analysis.
Academic Article Conformational behavior of Escherichia coli OmpA signal peptides in membrane mimetic environments.
Academic Article Side chain-backbone hydrogen bonding contributes to helix stability in peptides derived from an alpha-helical region of carboxypeptidase A.
Academic Article Hydrophobic content and lipid interactions of wild-type and mutant OmpA signal peptides correlate with their in vivo function.
Academic Article The conformation of a signal peptide bound by Escherichia coli preprotein translocase SecA.
Academic Article Finding the fittest fold: using the evolutionary record to design new proteins.
Academic Article Fluorescence analysis of tryptophan-containing variants of the LamB signal sequence upon insertion into a lipid bilayer.
Academic Article Conformational and membrane-binding properties of a signal sequence are largely unaltered by its adjacent mature region.
Academic Article Synthesis and crystal structures of Boc-L-Asn-L-Pro-OBzl.CH3OH and dehydration side product, Boc-beta-cyano-L-alanine-L-Pro-OBzl.
Academic Article Reduced tendency to form a beta turn in peptides from the P22 tailspike protein correlates with a temperature-sensitive folding defect.
Academic Article Helix formation and stability in a signal sequence.
Academic Article Functional and nonfunctional LamB signal sequences can be distinguished by their biophysical properties.
Academic Article An interdomain energetic tug-of-war creates the allosterically active state in Hsp70 molecular chaperones.
Academic Article The Role of Aromatic-Aromatic Interactions in Strand-Strand Stabilization of ß-Sheets.
Academic Article Characterization of a functionally important mobile domain of GroES.
Academic Article Conformational analysis of a highly potent dicyclic gonadotropin-releasing hormone antagonist by nuclear magnetic resonance and molecular dynamics.
Academic Article Conformation of a heptapeptide substrate bound to protein farnesyltransferase.
Academic Article The structure of Escherichia coli heat-stable enterotoxin b by nuclear magnetic resonance and circular dichroism.
Concept Molecular Sequence Data
Academic Article Comparing protein folding in vitro and in vivo: foldability meets the fitness challenge.

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  • Molecular Sequence Data