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Search Results to Lila M Gierasch Ph.D.

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One or more keywords matched the following items that are connected to Gierasch, Lila

Item TypeName
Academic Article The crystal structure of the GroES co-chaperonin at 2.8 A resolution.
Academic Article Intrinsic tryptophans of CRABPI as probes of structure and folding.
Academic Article Local interactions in a Schellman motif dictate interhelical arrangement in a protein fragment.
Academic Article Molecular chaperones: clamps for the Clps?
Academic Article Different conformations for the same polypeptide bound to chaperones DnaK and GroEL.
Academic Article Biophysical studies of recognition sequences for targeting and folding.
Academic Article Combined use of molecular dynamics simulations and NMR to explore peptide bond isomerization and multiple intramolecular hydrogen-bonding possibilities in a cyclic pentapeptide, cyclo(Gly-Pro-D-Phe-Gly-Val).
Academic Article Constrained peptides: models of bioactive peptides and protein substructures.
Academic Article Dynamics of cellular retinoic acid binding protein I on multiple time scales with implications for ligand binding.
Academic Article Mutating the charged residues in the binding pocket of cellular retinoic acid-binding protein simultaneously reduces its binding affinity to retinoic acid and increases its thermostability.
Academic Article The cost of exposing a hydrophobic loop and implications for the functional role of 4.5 S RNA in the Escherichia coli signal recognition particle.
Academic Article The LDL receptor clustering motif interacts with the clathrin terminal domain in a reverse turn conformation.
Academic Article Solution conformations of two flexible cyclic pentapeptides: cyclo(Gly-Pro-D-Phe-Gly-Ala) and cyclo(Gly-Pro-D-Phe-Gly-Val).
Academic Article Impact of a micellar environment on the conformations of two cyclic pentapeptides.
Academic Article Functionally significant mobile regions of Escherichia coli SecA ATPase identified by NMR.
Academic Article Recognition of nascent polypeptides for targeting and folding.
Academic Article Nucleotide exchange from the high-affinity ATP-binding site in SecA is the rate-limiting step in the ATPase cycle of the soluble enzyme and occurs through a specialized conformational state.
Academic Article Unfolding dynamics of a beta-sheet protein studied by mass spectrometry.
Academic Article Direct comparison of a stable isolated Hsp70 substrate-binding domain in the empty and substrate-bound states.
Academic Article Design of biologically active, conformationally constrained GnRH antagonists.
Academic Article Disorder breathes life into a DEAD motor.
Academic Article Multiple roles of prolyl residues in structure and folding.
Academic Article Cyclic pentapeptides as models for reverse turns: determination of the equilibrium distribution between type I and type II conformations of Pro-Asn and Pro-Ala beta-turns.
Academic Article Comparison of helix stability in wild-type and mutant LamB signal sequences.
Academic Article Defining the structure of the substrate-free state of the DnaK molecular chaperone.
Academic Article Nature's molecular sponges: small heat shock proteins grow into their chaperone roles.
Academic Article T-cell antigenic peptides from sperm whale myoglobin fold as amphipathic helices: a possible determinant for immunodominance?
Academic Article The chaperonin GroEL binds a polypeptide in an alpha-helical conformation.
Academic Article Native structural propensity in cellular retinoic acid-binding protein I 64-88: the role of locally encoded structure in the folding of a beta-barrel protein.
Academic Article Nuclear magnetic resonance analysis and conformational characterization of a cyclic decapeptide antagonist of gonadotropin-releasing hormone.
Academic Article The NPXY internalization signal of the LDL receptor adopts a reverse-turn conformation.
Academic Article Molecular mechanisms of protein secretion: the role of the signal sequence.
Academic Article Dynamics of a hydrophobic peptide in membrane bilayers by solid-state nuclear magnetic resonance.
Academic Article Dehydrophenylalanine can occur in various reverse-turn sites: conformational analysis of delta Phe-containing model peptides.
Academic Article Conformation-function relationships in hydrophobic peptides: interior turns and signal sequences.
Academic Article Interaction of peptides corresponding to mitochondrial presequences with membranes.
Academic Article Exploring the conformational roles of signal sequences: synthesis and conformational analysis of lambda receptor protein wild-type and mutant signal peptides.
Academic Article Conformations of model peptides in membrane-mimetic environments.
Academic Article Effect of charged residue substitutions on the membrane-interactive properties of signal sequences of the Escherichia coli LamB protein.
Academic Article Membrane-bound conformation of a signal peptide: a transferred nuclear Overhauser effect analysis.
Academic Article Equilibrium folding studies of cellular retinoic acid binding protein, a predominantly beta-sheet protein.
Academic Article Conformational behavior of Escherichia coli OmpA signal peptides in membrane mimetic environments.
Academic Article Side chain-backbone hydrogen bonding contributes to helix stability in peptides derived from an alpha-helical region of carboxypeptidase A.
Academic Article Hydrophobic content and lipid interactions of wild-type and mutant OmpA signal peptides correlate with their in vivo function.
Academic Article A well-defined amphipathic conformation for the calcium-free cyclic lipopeptide antibiotic, daptomycin, in aqueous solution.
Academic Article The conformation of a signal peptide bound by Escherichia coli preprotein translocase SecA.
Academic Article Natural polypeptide scaffolds: beta-sheets, beta-turns, and beta-hairpins.
Academic Article The changing landscape of protein allostery.
Academic Article Fluorescence analysis of tryptophan-containing variants of the LamB signal sequence upon insertion into a lipid bilayer.
Academic Article Conformational and membrane-binding properties of a signal sequence are largely unaltered by its adjacent mature region.
Academic Article Synthesis and crystal structures of Boc-L-Asn-L-Pro-OBzl.CH3OH and dehydration side product, Boc-beta-cyano-L-alanine-L-Pro-OBzl.
Academic Article Reduced tendency to form a beta turn in peptides from the P22 tailspike protein correlates with a temperature-sensitive folding defect.
Academic Article Orthogonal cross-seeding: an approach to explore protein aggregates in living cells.
Academic Article A method for direct measurement of protein stability in vivo.
Academic Article Conformations and orientations of a signal peptide interacting with phospholipid monolayers.
Academic Article Helix formation and stability in a signal sequence.
Academic Article Dynamic local unfolding in the serpin a-1 antitrypsin provides a mechanism for loop insertion and polymerization.
Academic Article Functional and nonfunctional LamB signal sequences can be distinguished by their biophysical properties.
Academic Article Conserved, disordered C terminus of DnaK enhances cellular survival upon stress and DnaK in vitro chaperone activity.
Academic Article Using a low denaturant model to explore the conformational features of translocation-active SecA.
Academic Article Turns in peptides and proteins.
Academic Article An interdomain energetic tug-of-war creates the allosterically active state in Hsp70 molecular chaperones.
Academic Article Conformations of signal peptides induced by lipids suggest initial steps in protein export.
Academic Article How bacteria survive an acid trip.
Academic Article In vivo function and membrane binding properties are correlated for Escherichia coli lamB signal peptides.
Academic Article Conformations of (X-L-Pro-Y)2 cyclic hexapeptides. Preferred beta-turn conformers and implications for beta turns in proteins.
Academic Article Polypeptide interactions with molecular chaperones and their relationship to in vivo protein folding.
Academic Article Characterization of a functionally important mobile domain of GroES.
Academic Article Conformational analysis of a highly potent dicyclic gonadotropin-releasing hormone antagonist by nuclear magnetic resonance and molecular dynamics.
Academic Article Conformation of a heptapeptide substrate bound to protein farnesyltransferase.
Academic Article The structure of Escherichia coli heat-stable enterotoxin b by nuclear magnetic resonance and circular dichroism.
Concept Protein Conformation
Academic Article ATPase subdomain IA is a mediator of interdomain allostery in Hsp70 molecular chaperones.
Academic Article Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs).
Academic Article Energy landscapes of functional proteins are inherently risky.
Academic Article Substrate-binding domain conformational dynamics mediate Hsp70 allostery.

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  • Protein Conformation