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Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells.
Defects of immune regulation in the presenilin-1 mutant knockin mouse.
Individual and combined presenilin 1 and 2 knockouts reveal that both have highly overlapping functions in HEK293T cells.
?-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse ?-secretase modulators do not.